| # | Title | Journal | Year | Citations |
|---|
| 1 | Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease | Nature Genetics | 2011 | 1,685 |
| 2 | High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease | Nature Genetics | 2006 | 1,363 |
| 3 | Polymyositis and dermatomyositis | Lancet, The | 2003 | 1,306 |
| 4 | EXTRACORPOREALLY INDUCED DESTRUCTION OF KIDNEY STONES BY SHOCK WAVES | Lancet, The | 1980 | 1,001 |
| 5 | CADASIL | Lancet Neurology, The | 2009 | 939 |
| 6 | Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine | Lancet, The | 2005 | 760 |
| 7 | Role of Kupffer cells in host defense and liver disease | Liver International | 2006 | 707 |
| 8 | Treatment and outcomes of acute basilar artery occlusion in the Basilar Artery International Cooperation Study (BASICS): a prospective registry study | Lancet Neurology, The | 2009 | 640 |
| 9 | Standard graft-versus-host disease prophylaxis with or without anti-T-cell globulin in haematopoietic cell transplantation from matched unrelated donors: a randomised, open-label, multicentre phase 3 trial | Lancet Oncology, The | 2009 | 620 |
| 10 | Randomized Phase III Trial of Gemcitabine Plus Cisplatin Compared With Gemcitabine Alone in Advanced Pancreatic Cancer | Journal of Clinical Oncology | 2006 | 619 |
| 11 | The phenotypic spectrum of CADASIL: Clinical findings in 102 cases | Annals of Neurology | 1998 | 618 |
| 12 | SCCT expert consensus document on computed tomography imaging before transcatheter aortic valve implantation (TAVI)/transcatheter aortic valve replacement (TAVR) | Journal of Cardiovascular Computed Tomography | 2012 | 532 |
| 13 | ESCMID guideline: diagnosis and treatment of acute bacterial meningitis | Clinical Microbiology and Infection | 2016 | 529 |
| 14 | Hyperthermia in oncology | International Journal of Hyperthermia | 2001 | 510 |
| 15 | Acute hepatitis C: high rate of both spontaneous and treatment-induced viral clearance1 1The Bundesministerium für Bildung und Forschung and the European Union, as sponsors of the study, had no role in study design, data collection, analysis, or interpretation or in the writing and the decision to submit the report for publication. | Gastroenterology | 2003 | 509 |
| 16 | Extended Treatment Duration for Hepatitis C Virus Type 1: Comparing 48 Versus 72 Weeks of Peginterferon-Alfa-2a Plus Ribavirin | Gastroenterology | 2006 | 500 |
| 17 | Pneumococcal meningitis in adults: Spectrum of complications and prognostic factors in a series of 87 cases | Brain | 2003 | 432 |
| 18 | Sonoporation from Jetting Cavitation Bubbles | Biophysical Journal | 2006 | 420 |
| 19 | Episodic vertigo related to migraine (90 cases): vestibular migraine? | Journal of Neurology | 1999 | 409 |
| 20 | Genome-wide association study of PR interval | Nature Genetics | 2010 | 400 |
| 21 | Vestibular cortex lesions affect the perception of verticality | Annals of Neurology | 1994 | 386 |
| 22 | Multisensory Cortical Signal Increases and Decreases During Vestibular Galvanic Stimulation (fMRI) | Journal of Neurophysiology | 2001 | 379 |
| 23 | Photodynamic Diagnosis of Non–muscle-invasive Bladder Cancer with Hexaminolevulinate Cystoscopy: A Meta-analysis of Detection and Recurrence Based on Raw Data | European Urology | 2013 | 372 |
| 24 | THE BENEFICIAL EFFECT OF HUMAN RECOMBINANT SUPEROXIDE DISMUTASE ON ACUTE AND CHRONIC REJECTION EVENTS IN RECIPIENTS OF CADAVERIC RENAL TRANSPLANTS | Transplantation | 1994 | 361 |
| 25 | Ocular torsion and tilt of subjective visual vertical are sensitive brainstem signs | Annals of Neurology | 2004 | 357 |
| 26 | Genome-wide association study reveals three susceptibility loci for common migraine in the general population | Nature Genetics | 2011 | 355 |
| 27 | Brain activation patterns during imagined stance and locomotion in functional magnetic resonance imaging | NeuroImage | 2004 | 340 |
| 28 | Cerebral generators involved in the pathogenesis of the restless legs syndrome | Annals of Neurology | 1997 | 338 |
| 29 | Vestibular syndromes in the roll plane: Topographic diagnosis from brainstem to cortex | Annals of Neurology | 1994 | 336 |
| 30 | Comparison of CT colonography, colonoscopy, sigmoidoscopy and faecal occult blood tests for the detection of advanced adenoma in an average risk population | Gut | 2009 | 334 |
| 31 | Biotechnological agents for the immunotherapy of multiple sclerosis. Principles, problems and perspectives | Brain | 1997 | 330 |
| 32 | The Vestibular Cortex: Its Locations, Functions, and Disorders | Annals of the New York Academy of Sciences | 1999 | 330 |
| 33 | Pregnancy outcomes after peripheral blood or bone marrow transplantation: a retrospective survey | Lancet, The | 2001 | 325 |
| 34 | Tumor markers in pancreatic cancer: a European Group on Tumor Markers (EGTM) status report | Annals of Oncology | 2010 | 300 |
| 35 | Clinical Characteristics and Frequency of the Hereditary Restless Legs Syndrome in a Population of 300 Patients | Sleep | 2000 | 299 |
| 36 | Association between HER-2/neu and Vascular Endothelial Growth Factor Expression Predicts Clinical Outcome in Primary Breast Cancer Patients | Clinical Cancer Research | 2004 | 297 |
| 37 | Phobic Postural Vertigo | Neurology | 1996 | 282 |
| 38 | Chronic graft-versus-host disease: long-term results from a randomized trial on graft-versus-host disease prophylaxis with or without anti–T-cell globulin ATG-Fresenius | Blood | 2011 | 281 |
| 39 | Myocardial oxygen consumption in chronic heart disease: Role of wall stress, hypertrophy and coronary reserve | American Journal of Cardiology | 1979 | 278 |
| 40 | Increased Formation of Reactive Oxygen Species after Permanent and Reversible Middle Cerebral Artery Occlusion in the Rat | Journal of Cerebral Blood Flow and Metabolism | 1998 | 274 |
| 41 | Definitions, methodology and therapeutic strategies in portal hypertension | Journal of Hepatology | 1992 | 273 |
| 42 | Diagnostic accuracy of dual-source multi-slice CT-coronary angiography in patients with an intermediate pretest likelihood for coronary artery disease | European Heart Journal | 2007 | 270 |
| 43 | Wallenberg's syndrome: Lateropulsion, cyclorotation, and subjective visual vertical in thirty-six patients | Annals of Neurology | 1992 | 267 |
| 44 | Nitric Oxide Scavenging by Hemoglobin or Nitric Oxide Synthase Inhibition by N-Nitro-L-Arginine Induces Cortical Spreading Ischemia When K+ Is Increased in the Subarachnoid Space | Journal of Cerebral Blood Flow and Metabolism | 1998 | 267 |
| 45 | γ-secretase directly sheds the survival receptor BCMA from plasma cells | Nature Communications | 2015 | 267 |
| 46 | IN-UTERO EXPOSURE TO VALPROATE AND NEURAL TUBE DEFECTS | Lancet, The | 1986 | 265 |
| 47 | Screening for MLL tandem duplication in 387 unselected patients with AML identify a prognostically unfavorable subset of AML | Leukemia | 2000 | 262 |
| 48 | Neurotrophic cross-talk between the nervous and immune systems: Implications for neurological diseases | Annals of Neurology | 2003 | 260 |
| 49 | Latent Herpesvirus Infection in Human Trigeminal Ganglia Causes Chronic Immune Response | American Journal of Pathology | 2003 | 257 |
| 50 | Long-term prognosis and causes of death in CADASIL: a retrospective study in 411 patients | Brain | 2004 | 253 |
