| # | Title | Journal | Year | Citations |
|---|
| 1 | Paclitaxel plus Bevacizumab versus Paclitaxel Alone for Metastatic Breast Cancer | New England Journal of Medicine | 2007 | 2,865 |
| 2 | Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index | Nature Genetics | 2010 | 2,634 |
| 3 | The Patient-Reported Outcomes Measurement Information System (PROMIS) | Medical Care | 2007 | 2,314 |
| 4 | Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008 | Intensive Care Medicine | 2008 | 2,078 |
| 5 | 2015 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis | Arthritis and Rheumatology | 2016 | 1,880 |
| 6 | Defining the role of common variation in the genomic and biological architecture of adult human height | Nature Genetics | 2014 | 1,818 |
| 7 | Percutaneous Repair or Surgery for Mitral Regurgitation | New England Journal of Medicine | 2011 | 1,814 |
| 8 | Hundreds of variants clustered in genomic loci and biological pathways affect human height | Nature | 2010 | 1,789 |
| 9 | Definition, evaluation, and classification of renal osteodystrophy: A position statement from Kidney Disease: Improving Global Outcomes (KDIGO) | Kidney International | 2006 | 1,586 |
| 10 | Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma | Nature Genetics | 2015 | 1,491 |
| 11 | Association of Risk-Reducing Surgery in <emph type="ital">BRCA1</emph> or <emph type="ital">BRCA2</emph> Mutation Carriers With Cancer Risk and Mortality | JAMA - Journal of the American Medical Association | 2010 | 1,241 |
| 12 | Genome-wide association study identifies 74 loci associated with educational attainment | Nature | 2016 | 1,204 |
| 13 | Guidelines of care for the management of psoriasis and psoriatic arthritis | Journal of the American Academy of Dermatology | 2008 | 1,128 |
| 14 | Impact of Cancer‐Related Fatigue on the Lives of Patients: New Findings From the Fatigue Coalition | Oncologist | 2000 | 1,048 |
| 15 | Etanercept and clinical outcomes, fatigue, and depression in psoriasis: double-blind placebo-controlled randomised phase III trial | Lancet, The | 2006 | 979 |
| 16 | The Self–Stigma of Mental Illness: Implications for Self–Esteem and Self–Efficacy | Journal of Social and Clinical Psychology | 2006 | 939 |
| 17 | Mapping genomic loci implicates genes and synaptic biology in schizophrenia | Nature | 2022 | 929 |
| 18 | 2015 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis | Arthritis Care and Research | 2016 | 890 |
| 19 | Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects | Nature Genetics | 2017 | 838 |
| 20 | Plasmid-Mediated Quinolone Resistance: a Multifaceted Threat | Clinical Microbiology Reviews | 2009 | 786 |
| 21 | Chemohormonal Therapy in Metastatic Hormone-Sensitive Prostate Cancer: Long-Term Survival Analysis of the Randomized Phase III E3805 CHAARTED Trial | Journal of Clinical Oncology | 2018 | 702 |
| 22 | The evolutionary history of 2,658 cancers | Nature | 2020 | 690 |
| 23 | NovoTTF-100A versus physician’s choice chemotherapy in recurrent glioblastoma: A randomised phase III trial of a novel treatment modality | European Journal of Cancer | 2012 | 661 |
| 24 | A Prospective, Multi-institutional, Pathologist-Based Assessment of 4 Immunohistochemistry Assays for PD-L1 Expression in Non–Small Cell Lung Cancer | JAMA Oncology | 2017 | 658 |
| 25 | Prevalence in the United States of aac(6 ′ ) - Ib - cr Encoding a Ciprofloxacin-Modifying Enzyme | Antimicrobial Agents and Chemotherapy | 2006 | 657 |
| 26 | Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci | Nature Genetics | 2018 | 652 |
| 27 | Breast Cancer—Major changes in the American Joint Committee on Cancer eighth edition cancer staging manual | Ca-A Cancer Journal for Clinicians | 2017 | 649 |
| 28 | American Cancer Society Guidelines for Breast Cancer Screening: Update 2003 | Ca-A Cancer Journal for Clinicians | 2003 | 636 |
| 29 | Evaluation of Item Candidates | Medical Care | 2007 | 632 |
| 30 | American Cancer Society Guidelines for the Early Detection of Cancer | Ca-A Cancer Journal for Clinicians | 2002 | 615 |
| 31 | Influence of Controllable Lifestyle on Recent Trends in Specialty Choice by US Medical Students | JAMA - Journal of the American Medical Association | 2003 | 587 |
| 32 | Symptom prevalence, duration, and risk of hospital admission in individuals infected with SARS-CoV-2 during periods of omicron and delta variant dominance: a prospective observational study from the ZOE COVID Study | Lancet, The | 2022 | 547 |
| 33 | Residual Neuromuscular Blockade and Critical Respiratory Events in the Postanesthesia Care Unit | Anesthesia and Analgesia | 2008 | 540 |
| 34 | Measuring financial toxicity as a clinically relevant patient‐reported outcome: The validation of the COmprehensive Score for financial Toxicity (COST) | Cancer | 2017 | 522 |
| 35 | Acute and 12-Month Results With Catheter-Based Mitral Valve Leaflet Repair | Journal of the American College of Cardiology | 2012 | 518 |
| 36 | Human TUBB3 Mutations Perturb Microtubule Dynamics, Kinesin Interactions, and Axon Guidance | Cell | 2010 | 515 |
| 37 | Comparison of coronary bypass surgery with drug-eluting stenting for the treatment of left main and/or three-vessel disease: 3-year follow-up of the SYNTAX trial | European Heart Journal | 2011 | 506 |
| 38 | Comprehensive Research Synopsis and Systematic Meta-Analyses in Parkinson's Disease Genetics: The PDGene Database | PLoS Genetics | 2012 | 495 |
| 39 | Initial results from a prospective cohort study of 5583 cases of thyroid carcinoma treated in the United States during 1996 | Cancer | 2000 | 468 |
| 40 | Guidelines of care for the management of psoriasis and psoriatic arthritis | Journal of the American Academy of Dermatology | 2008 | 456 |
| 41 | Clinical pharmacogenetics implementation consortium guideline (CPIC) for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants: 2016 update | Clinical Pharmacology and Therapeutics | 2017 | 450 |
| 42 | The role of stereotactic radiosurgery in the management of patients with newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline | Journal of Neuro-Oncology | 2010 | 446 |
| 43 | Esophageal cancer: results of an American College of Surgeons patient care evaluation study11No competing interests declared. | Journal of the American College of Surgeons | 2000 | 436 |
| 44 | A Guide to Utilization of the Microbiology Laboratory for Diagnosis of Infectious Diseases: 2013 Recommendations by the Infectious Diseases Society of America (IDSA) and the American Society for Microbiology (ASM)a | Clinical Infectious Diseases | 2013 | 426 |
| 45 | Role of subconcussion in repetitive mild traumatic brain injury | Journal of Neurosurgery | 2013 | 424 |
| 46 | Multicenter Comparison of Machine Learning Methods and Conventional Regression for Predicting Clinical Deterioration on the Wards | Critical Care Medicine | 2016 | 423 |
| 47 | Guidelines of care for the management of psoriasis and psoriatic arthritis | Journal of the American Academy of Dermatology | 2009 | 419 |
| 48 | Standardizing terms for clinical pharmacogenetic test results: consensus terms from the Clinical Pharmacogenetics Implementation Consortium (CPIC) | Genetics in Medicine | 2017 | 410 |
| 49 | Relationship between changes in hemoglobin level and quality of life during chemotherapy in anemic cancer patients receiving epoetin alfa therapy | Cancer | 2002 | 398 |
| 50 | Guidelines of care for the management of psoriasis and psoriatic arthritis | Journal of the American Academy of Dermatology | 2011 | 398 |
