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1The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)JAMA - Journal of the American Medical Association201616,554
2Adverse Renal Effects of Immune Checkpoint Inhibitors: A Narrative ReviewAmerican Journal of Nephrology201710,656
3Guidelines for the Management of Severe Traumatic Brain Injury, Fourth EditionNeurosurgery20172,457
4American Association of Oral and Maxillofacial Surgeons Position Paper on Medication-Related Osteonecrosis of the Jaw—2014 UpdateJournal of Oral and Maxillofacial Surgery20142,019
5Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individualsNature Genetics20181,835
6Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancerJournal of Experimental Medicine20171,582
7Congenital Adrenal Hyperplasia Due to Steroid 21-Hydroxylase Deficiency: An Endocrine Society Clinical Practice GuidelineJournal of Clinical Endocrinology and Metabolism20101,117
8Prevalence, incidence and mortality from cardiovascular disease in patients with pooled and specific severe mental illness: a large‐scale meta‐analysis of 3,211,768 patients and 113,383,368 controlsWorld Psychiatry20171,082
9Resistance Mechanisms for the Bruton's Tyrosine Kinase Inhibitor IbrutinibNew England Journal of Medicine20141,042
10Pembrolizumab in advanced soft-tissue sarcoma and bone sarcoma (SARC028): a multicentre, two-cohort, single-arm, open-label, phase 2 trialLancet Oncology, The2017921
11Definition of clinically relevant non‐major bleeding in studies of anticoagulants in atrial fibrillation and venous thromboembolic disease in non‐surgical patients: communication from the SSC of the ISTHJournal of Thrombosis and Haemostasis2015889
12Acute myeloid leukemia ontogeny is defined by distinct somatic mutationsBlood2015747
13Vagus nerve stimulation inhibits cytokine production and attenuates disease severity in rheumatoid arthritisProceedings of the National Academy of Sciences of the United States of America2016742
14Socioeconomic Status and Cardiovascular OutcomesCirculation2018737
15SchizophreniaNature Reviews Disease Primers2015724
16Deep brain stimulation: current challenges and future directionsNature Reviews Neurology2019721
17Anifrolumab, an Anti–Interferon‐α Receptor Monoclonal Antibody, in Moderate‐to‐Severe Systemic Lupus ErythematosusArthritis and Rheumatology2017634
18Guideline update for MASCC and ESMO in the prevention of chemotherapy- and radiotherapy-induced nausea and vomiting: results of the Perugia consensus conferenceAnnals of Oncology2010585
19Cognitive Load Theory: Implications for medical education: AMEE Guide No. 86Medical Teacher2014516
20Better Tests, Better Care: Improved Diagnostics for Infectious DiseasesClinical Infectious Diseases2013496
21Proposal of a New Adverse Event Classification by the Society of Interventional Radiology Standards of Practice CommitteeJournal of Vascular and Interventional Radiology2017481
22Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysisLancet, The2018452
23HRS Expert Consensus Statement on remote interrogation and monitoring for cardiovascular implantable electronic devicesHeart Rhythm2015449
24Use of PER977 to Reverse the Anticoagulant Effect of EdoxabanNew England Journal of Medicine2014408
25Off-Label Dosing of Non-Vitamin K Antagonist Oral Anticoagulants and Adverse OutcomesJournal of the American College of Cardiology2016401
26The Surgical Infection Society Revised Guidelines on the Management of Intra-Abdominal InfectionSurgical Infections2017382
27Cancer Screening Recommendations for Individuals with Li-Fraumeni SyndromeClinical Cancer Research2017358
28Immediate neurophysiological effects of transcranial electrical stimulationNature Communications2018338
29Management of Acute Myocardial Infarction During the COVID-19 PandemicJournal of the American College of Cardiology2020335
30American Society of Hematology 2018 guidelines for management of venous thromboembolism: optimal management of anticoagulation therapyBlood Advances2018328
31American Association of Oral and Maxillofacial Surgeons’ Position Paper on Medication-Related Osteonecrosis of the Jaws—2022 UpdateJournal of Oral and Maxillofacial Surgery2022312
32Universal definition of perioperative bleeding in adult cardiac surgeryJournal of Thoracic and Cardiovascular Surgery2014301
33Venetoclax plus rituximab in relapsed or refractory chronic lymphocytic leukaemia: a phase 1b studyLancet Oncology, The2017287
34Phase Ib Study of PEGylated Recombinant Human Hyaluronidase and Gemcitabine in Patients with Advanced Pancreatic CancerClinical Cancer Research2016272
35Management of adverse events associated with idelalisib treatment: expert panel opinionLeukemia and Lymphoma2015268
36The Use of Long-Acting Injectable Antipsychotics in SchizophreniaJournal of Clinical Psychiatry2016267
37Symbolic gestures and spoken language are processed by a common neural systemProceedings of the National Academy of Sciences of the United States of America2009262
38Value of platelet/lymphocyte ratio as a predictor of all-cause mortality after non-ST-elevation myocardial infarctionJournal of Thrombosis and Thrombolysis2012258
39Sex- and Age-Adjusted Population Analysis of Prevalence Estimates for Hidradenitis Suppurativa in the United StatesJAMA Dermatology2017258
40Spatiotemporal structure of intracranial electric fields induced by transcranial electric stimulation in humans and nonhuman primatesScientific Reports2016256
41Persistence of multiple illnesses in World Trade Center rescue and recovery workers: a cohort studyLancet, The2011255
42Current trends in inflammatory and immunomodulatory mediators in sepsisJournal of Leukocyte Biology2012244
43Targeting Bruton tyrosine kinase with ibrutinib in relapsed/refractory marginal zone lymphomaBlood2017243
44Hypersensitivity reactions to intravenous iron: guidance for risk minimization and managementHaematologica2014235
45Associations of Ambient Air Pollution with Chronic Obstructive Pulmonary Disease Hospitalization and MortalityAmerican Journal of Respiratory and Critical Care Medicine2013234
46Seven-Year Follow-Up Analysis of Adjuvant Paclitaxel and Trastuzumab Trial for Node-Negative, Human Epidermal Growth Factor Receptor 2–Positive Breast CancerJournal of Clinical Oncology2019229
47Medication-Related Osteonecrosis of the Jaw: MASCC/ISOO/ASCO Clinical Practice GuidelineJournal of Clinical Oncology2019224
48Sinusoidal Obstruction Syndrome (Hepatic Veno-Occlusive Disease)Journal of Clinical and Experimental Hepatology2014214
49Extended follow-up and impact of high-risk prognostic factors from the phase 3 RESONATE study in patients with previously treated CLL/SLLLeukemia2018205
50Clinical phenotypes of perinatal depression and time of symptom onset: analysis of data from an international consortiumLancet Psychiatry,the2017199