| # | Title | Journal | Year | Citations |
|---|
| 1 | Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines | Journal of Extracellular Vesicles | 2018 | 6,961 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 3 | Cellular Senescence: Defining a Path Forward | Cell | 2019 | 1,551 |
| 4 | Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: living systematic review and meta-analysis | BMJ, The | 2020 | 1,474 |
| 5 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 6 | Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data | BMJ: British Medical Journal | 2017 | 1,408 |
| 7 | Inflammation in neurodegenerative diseases | Immunology | 2010 | 1,104 |
| 8 | Alemtuzumab versus interferon beta 1a as first-line treatment for patients with relapsing-remitting multiple sclerosis: a randomised controlled phase 3 trial | Lancet, The | 2012 | 1,041 |
| 9 | Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) | European Journal of Immunology | 2019 | 766 |
| 10 | Respiratory risks from household air pollution in low and middle income countries | Lancet Respiratory Medicine,the | 2014 | 670 |
| 11 | The systemic immune response to trauma: an overview of pathophysiology and treatment | Lancet, The | 2014 | 607 |
| 12 | Metalloproteinases and Wound Healing | Advances in Wound Care | 2015 | 575 |
| 13 | Pervasive Sharing of Genetic Effects in Autoimmune Disease | PLoS Genetics | 2011 | 540 |
| 14 | Genome-wide Analyses Identify KIF5A as a Novel ALS Gene | Neuron | 2018 | 517 |
| 15 | Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis | Nature Genetics | 2016 | 494 |
| 16 | Functional definition and characterization of acute traumatic coagulopathy | Critical Care Medicine | 2011 | 454 |
| 17 | Evolution and transmission of drug-resistant tuberculosis in a Russian population | Nature Genetics | 2014 | 451 |
| 18 | Inflammation in neurodegenerative diseases – an update | Immunology | 2014 | 434 |
| 19 | Hepatitis C virus treatment for prevention among people who inject drugs: Modeling treatment scale-up in the age of direct-acting antivirals | Hepatology | 2013 | 431 |
| 20 | Impact of direct acting antiviral therapy in patients with chronic hepatitis C and decompensated cirrhosis | Journal of Hepatology | 2016 | 425 |
| 21 | Immune Dysfunction as a Cause and Consequence of Malnutrition | Trends in Immunology | 2016 | 411 |
| 22 | Esophageal Disorders | Gastroenterology | 2016 | 411 |
| 23 | Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis | Nature Neuroscience | 2014 | 398 |
| 24 | Increased Neurofilament Light Chain Blood Levels in Neurodegenerative Neurological Diseases | PLoS ONE | 2013 | 375 |
| 25 | The power of genetic diversity in genome-wide association studies of lipids | Nature | 2021 | 353 |
| 26 | Anorectal Disorders | Gastroenterology | 2016 | 350 |
| 27 | Can probiotics modulate human disease by impacting intestinal barrier function? | British Journal of Nutrition | 2017 | 343 |
| 28 | Cell2location maps fine-grained cell types in spatial transcriptomics | Nature Biotechnology | 2022 | 335 |
| 29 | Global prevalence and disease burden of vitamin D deficiency: a roadmap for action in low‐ and middle‐income countries | Annals of the New York Academy of Sciences | 2018 | 330 |
| 30 | Monitoring Tumorigenesis and Senescence In Vivo with a p16INK4a-Luciferase Model | Cell | 2013 | 325 |
| 31 | Microbiome–host systems interactions: protective effects of propionate upon the blood–brain barrier | Microbiome | 2018 | 324 |
| 32 | Porphyromonas gingivalis Manipulates Complement and TLR Signaling to Uncouple Bacterial Clearance from Inflammation and Promote Dysbiosis | Cell Host and Microbe | 2014 | 318 |
| 33 | A Novel Variant, NDM-5, of the New Delhi Metallo-β-Lactamase in a Multidrug-Resistant Escherichia coli ST648 Isolate Recovered from a Patient in the United Kingdom | Antimicrobial Agents and Chemotherapy | 2011 | 312 |
| 34 | The Transcription Factor T-bet Regulates Intestinal Inflammation Mediated by Interleukin-7 Receptor+ Innate Lymphoid Cells | Immunity | 2012 | 305 |
| 35 | Oligodendrocyte‐microglia cross‐talk in the central nervous system | Immunology | 2014 | 299 |
| 36 | Large C9orf72 Hexanucleotide Repeat Expansions Are Seen in Multiple Neurodegenerative Syndromes and Are More Frequent Than Expected in the UK Population | American Journal of Human Genetics | 2013 | 297 |
| 37 | Cerebrospinal fluid oligoclonal bands in multiple sclerosis and clinically isolated syndromes: a meta-analysis of prevalence, prognosis and effect of latitude | Journal of Neurology, Neurosurgery and Psychiatry | 2013 | 293 |
| 38 | Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose | Science | 2021 | 286 |
| 39 | Inflammatory Skin and Bowel Disease Linked toADAM17Deletion | New England Journal of Medicine | 2011 | 285 |
| 40 | Multidrug-resistant Acinetobacter baumannii: mechanisms of virulence and resistance | International Journal of Antimicrobial Agents | 2010 | 280 |
| 41 | Selective Sorting of Cargo Proteins into Bacterial Membrane Vesicles | Journal of Biological Chemistry | 2011 | 280 |
| 42 | Brain health: time matters in multiple sclerosis | Multiple Sclerosis and Related Disorders | 2016 | 280 |
| 43 | Pre-existing polymerase-specific T cells expand in abortive seronegative SARS-CoV-2 | Nature | 2022 | 280 |
| 44 | Identification of rare sequence variation underlying heritable pulmonary arterial hypertension | Nature Communications | 2018 | 279 |
| 45 | Daclizumab high-yield process in relapsing-remitting multiple sclerosis (SELECT): a randomised, double-blind, placebo-controlled trial | Lancet, The | 2013 | 269 |
| 46 | Cells of the human intestinal tract mapped across space and time | Nature | 2021 | 266 |
| 47 | Cross-tissue immune cell analysis reveals tissue-specific features in humans | Science | 2022 | 265 |
| 48 | Developmental cell programs are co-opted in inflammatory skin disease | Science | 2021 | 264 |
| 49 | Whole home exercise intervention for depression in older care home residents (the OPERA study): a process evaluation | BMC Medicine | 2014 | 260 |
| 50 | Vitamin D deficiency contributes directly to the acute respiratory distress syndrome (ARDS) | Thorax | 2015 | 258 |
