| # | Title | Journal | Year | Citations |
|---|
| 1 | Clinically Applicable AI System for Accurate Diagnosis, Quantitative Measurements, and Prognosis of COVID-19 Pneumonia Using Computed Tomography | Cell | 2020 | 638 |
| 2 | The RNA m6A reader YTHDC1 silences retrotransposons and guards ES cell identity | Nature | 2021 | 187 |
| 3 | REINVENT 2.0: An AI Tool for De Novo Drug Design | Journal of Chemical Information and Modeling | 2020 | 170 |
| 4 | Molecular Targets Related Drug Resistance Mechanisms in MDR-, XDR-, and TDR-Mycobacterium tuberculosis Strains | Frontiers in Cellular and Infection Microbiology | 2018 | 121 |
| 5 | Pyrazolo[1,5-a]pyridine Inhibitor of the Respiratory Cytochrome bcc Complex for the Treatment of Drug-Resistant Tuberculosis | ACS Infectious Diseases | 2019 | 74 |
| 6 | Hypoxia Induces Mitochondrial Defect That Promotes T Cell Exhaustion in Tumor Microenvironment Through MYC-Regulated Pathways | Frontiers in Immunology | 2020 | 65 |
| 7 | A novel mitochondrial micropeptide MPM enhances mitochondrial respiratory activity and promotes myogenic differentiation | Cell Death and Disease | 2019 | 49 |
| 8 | Mitochondrial DNA mutation exacerbates female reproductive aging via impairment of the NADH/NAD+ redox | Aging Cell | 2020 | 48 |
| 9 | Direct Nucleus‐Targeted Drug Delivery Using Cascade pHe/Photo Dual‐Sensitive Polymeric Nanocarrier for Cancer Therapy | Small | 2019 | 35 |
| 10 | Permissive epigenomes endow reprogramming competence to transcriptional regulators | Nature Chemical Biology | 2021 | 35 |
| 11 | MicroRNA-10 negatively regulates inflammation in diabetic kidney via targeting activation of the NLRP3 inflammasome | Molecular Therapy | 2021 | 35 |
| 12 | Inverse Association Between Riboflavin Intake and New-Onset Hypertension | Hypertension | 2020 | 33 |
| 13 | Temperature dependence of the SARS-CoV-2 affinity to human ACE2 determines COVID-19 progression and clinical outcome | Computational and Structural Biotechnology Journal | 2021 | 33 |
| 14 | Dietary Carbohydrate Intake and New-Onset Hypertension: A Nationwide Cohort Study in China | Hypertension | 2021 | 33 |
| 15 | Using Single-Cell and Spatial Transcriptomes to Understand Stem Cell Lineage Specification During Early Embryo Development | Annual Review of Genomics and Human Genetics | 2020 | 31 |
| 16 | TRIM21–SERPINB5 aids GMPS repression to protect nasopharyngeal carcinoma cells from radiation-induced apoptosis | Journal of Biomedical Science | 2020 | 30 |
| 17 | Predicted fat mass and lean mass in relation to all‐cause and cause‐specific mortality | Journal of Cachexia, Sarcopenia and Muscle | 2022 | 29 |
| 18 | Detection of novel mutations associated with independent resistance and cross-resistance to isoniazid and prothionamide in Mycobacterium tuberculosis clinical isolates | Clinical Microbiology and Infection | 2019 | 27 |
| 19 | DNA methylation markers in the diagnosis and prognosis of common leukemias | Signal Transduction and Targeted Therapy | 2020 | 27 |
| 20 | Association of Depressive Symptoms with Rapid Kidney Function Decline in Adults with Normal Kidney Function | Clinical Journal of the American Society of Nephrology: CJASN | 2021 | 25 |
| 21 | Impaired lipid metabolism by age-dependent DNA methylation alterations accelerates aging | Proceedings of the National Academy of Sciences of the United States of America | 2020 | 24 |
| 22 | N6‐methyladenosine Steers RNA Metabolism and Regulation in Cancer | Cancer Communications | 2021 | 24 |
| 23 | U-shaped association between dietary copper intake and new-onset hypertension | Clinical Nutrition | 2022 | 24 |
| 24 | Super resolution microscopy reveals how elongating RNA polymerase II and nascent RNA interact with nucleosome clutches | Nucleic Acids Research | 2022 | 24 |
| 25 | Occupational Physical Activity and New-Onset Hypertension: A Nationwide Cohort Study in China | Hypertension | 2021 | 21 |
| 26 | Quantity and variety of food groups consumption and the risk of diabetes in adults: A prospective cohort study | Clinical Nutrition | 2021 | 20 |
| 27 | Serum alkaline phosphatase levels and the risk of new-onset diabetes in hypertensive adults | Cardiovascular Diabetology | 2020 | 19 |
| 28 | Multiple GPCR Functional Assays Based on Resonance Energy Transfer Sensors | Frontiers in Cell and Developmental Biology | 2021 | 19 |
| 29 | The Role of Calmodulin vs. Synaptotagmin in Exocytosis | Frontiers in Molecular Neuroscience | 2021 | 19 |
| 30 | U-shaped Association Between Dietary Zinc Intake and New-onset Diabetes: A Nationwide Cohort Study in China | Journal of Clinical Endocrinology and Metabolism | 2022 | 19 |
| 31 | Identification of Pyrazolo[1,5-a]pyridine-3-carboxamide Diaryl Derivatives as Drug Resistant Antituberculosis Agents | ACS Medicinal Chemistry Letters | 2019 | 18 |
| 32 | High‐coverage SARS‐CoV‐2 genome sequences acquired by target capture sequencing | Journal of Medical Virology | 2020 | 17 |
| 33 | Histone demethylase KDM6A promotes somatic cell reprogramming by epigenetically regulating the PTEN and IL-6 signal pathways | Stem Cells | 2020 | 17 |
| 34 | OPA1-Exon4b Binds to mtDNA D-Loop for Transcriptional and Metabolic Modulation, Independent of Mitochondrial Fusion | Frontiers in Cell and Developmental Biology | 2020 | 17 |
| 35 | Engineering of leucine-responsive regulatory protein improves spiramycin and bitespiramycin biosynthesis | Microbial Cell Factories | 2019 | 16 |
| 36 | MicroRNA-10a/b inhibit TGF-β/Smad-induced renal fibrosis by targeting TGF-β receptor 1 in diabetic kidney disease | Molecular Therapy - Nucleic Acids | 2022 | 16 |
| 37 | Relationship of several serum folate forms with the risk of mortality: A prospective cohort study | Clinical Nutrition | 2021 | 14 |
| 38 | Emerging Insights into Keratin 16 Expression during Metastatic Progression of Breast Cancer | Cancers | 2021 | 14 |
| 39 | Establishment of human distal lung organoids for SARS-CoV-2 infection | Cell Discovery | 2021 | 14 |
| 40 | Variety and quantity of dietary protein intake from different sources and risk of new-onset diabetes: a Nationwide Cohort Study in China | BMC Medicine | 2022 | 14 |
| 41 | Inverse Association Between Variety of Proteins With Appropriate Quantity From Different Food Sources and New-Onset Hypertension | Hypertension | 2022 | 14 |
| 42 | The Hippo pathway component Wwc2 is a key regulator of embryonic development and angiogenesis in mice | Cell Death and Disease | 2021 | 13 |
| 43 | Phytochemical library screening reveals betulinic acid as a novel Skp2‐SCF E3 ligase inhibitor in non–small cell lung cancer | Cancer Science | 2021 | 13 |
| 44 | Paired box 6 programs essential exocytotic genes in the regulation of glucose-stimulated insulin secretion and glucose homeostasis | Science Translational Medicine | 2021 | 13 |
| 45 | 5-IP7 is a GPCR messenger mediating neural control of synaptotagmin-dependent insulin exocytosis and glucose homeostasis | Nature Metabolism | 2021 | 13 |
| 46 | Degree and duration of hypokalemia associated with peritonitis in patients undergoing peritoneal dialysis | International Journal of Clinical Practice | 2021 | 12 |
| 47 | Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike | PLoS Pathogens | 2022 | 12 |
| 48 | Personalized hydrogels for individual health care: preparation, features, and applications in tissue engineering | Materials Today Chemistry | 2021 | 11 |
| 49 | Naloxone regulates the differentiation of neural stem cells via a receptor‐independent pathway | FASEB Journal | 2020 | 10 |
| 50 | Comparative Analysis of Whole-Genome and Methylome Profiles of a Smooth and a Rough Mycobacterium abscessus Clinical Strain | G3: Genes, Genomes, Genetics | 2020 | 10 |
