| # | Title | Journal | Year | Citations |
|---|
| 1 | Can Treatment Adherence Be Improved by Using Rubin's Four Tendencies Framework to Understand a Patient's Response to Expectations | Biomedicine Hub | 2017 | 2,630 |
| 2 | TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis | Biochemical and Biophysical Research Communications | 2006 | 2,248 |
| 3 | Long-term postoperative cognitive dysfunction in the elderly: ISPOCD1 study | Lancet, The | 1998 | 2,163 |
| 4 | Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17 | Nature | 2006 | 1,816 |
| 5 | Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease | Nature Genetics | 2011 | 1,708 |
| 6 | Secukinumab in Plaque Psoriasis — Results of Two Phase 3 Trials | New England Journal of Medicine | 2014 | 1,675 |
| 7 | Pathogenesis and clinical features of psoriasis | Lancet, The | 2007 | 1,617 |
| 8 | Patient survival after D1 and D2 resections for gastric cancer: long-term results of the MRC randomized surgical trial | British Journal of Cancer | 1999 | 1,327 |
| 9 | Genome-wide association study identifies 74 loci associated with educational attainment | Nature | 2016 | 1,204 |
| 10 | Infliximab induction and maintenance therapy for moderate-to-severe psoriasis: a phase III, multicentre, double-blind trial | Lancet, The | 2005 | 975 |
| 11 | Postoperative morbidity and mortality after D1 and D2 resections for gastric cancer: preliminary results of the MRC randomised controlled surgical trial | Lancet, The | 1996 | 951 |
| 12 | The cortical representation of pain | Pain | 1999 | 925 |
| 13 | Long-term management of moderate-to-severe atopic dermatitis with dupilumab and concomitant topical corticosteroids (LIBERTY AD CHRONOS): a 1-year, randomised, double-blinded, placebo-controlled, phase 3 trial | Lancet, The | 2017 | 884 |
| 14 | Interleukin-1 and neuronal injury | Nature Reviews Immunology | 2005 | 864 |
| 15 | Trends in head injury outcome from 1989 to 2003 and the effect of neurosurgical care: an observational study | Lancet, The | 2005 | 863 |
| 16 | Cytokines and the nervous system II: actions and mechanisms of action | Trends in Neurosciences | 1995 | 840 |
| 17 | A harmonized classification system for FTLD-TDP pathology | Acta Neuropathologica | 2011 | 817 |
| 18 | Physical activity in older age: perspectives for healthy ageing and frailty | Biogerontology | 2016 | 767 |
| 19 | Comparison of ixekizumab with etanercept or placebo in moderate-to-severe psoriasis (UNCOVER-2 and UNCOVER-3): results from two phase 3 randomised trials | Lancet, The | 2015 | 719 |
| 20 | Patient safety incidents associated with airway devices in critical care: a review of reports to the UK National Patient Safety Agency | Anaesthesia | 2009 | 689 |
| 21 | Efficacy and safety of guselkumab, an anti-interleukin-23 monoclonal antibody, compared with adalimumab for the continuous treatment of patients with moderate to severe psoriasis: Results from the phase III, double-blinded, placebo- and active comparator–controlled VOYAGE 1 trial | Journal of the American Academy of Dermatology | 2017 | 673 |
| 22 | Cytokines and the nervous system I: expression and recognition | Trends in Neurosciences | 1995 | 639 |
| 23 | A multicenter, prospective, randomized, double-blind, placebo-controlled trial of corticosteroids and intravenous cyclophosphamide followed by oral azathioprine for the treatment of pulmonary fibrosis in scleroderma | Arthritis and Rheumatism | 2006 | 632 |
| 24 | Social and Psychological Burden of Dysphagia: Its Impact on Diagnosis and Treatment | Dysphagia | 2002 | 630 |
| 25 | Campylobacters as zoonotic pathogens: A food production perspective | International Journal of Food Microbiology | 2007 | 612 |
| 26 | Pain processing during three levels of noxious stimulation produces differential patterns of central activity | Pain | 1997 | 547 |
| 27 | Efficacy and safety of minimally invasive surgery with thrombolysis in intracerebral haemorrhage evacuation (MISTIE III): a randomised, controlled, open-label, blinded endpoint phase 3 trial | Lancet, The | 2019 | 534 |
| 28 | α‐Synuclein implicated in Parkinson's disease is present in extracellular biological fluids, including human plasma | FASEB Journal | 2003 | 520 |
| 29 | Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue') | Gastroenterology | 1992 | 512 |
| 30 | Apremilast, an oral phosphodiesterase 4 (PDE4) inhibitor, in patients with moderate to severe plaque psoriasis: Results of a phase III, randomized, controlled trial (Efficacy and Safety Trial Evaluating the Effects of Apremilast in Psoriasis [ESTEEM] 1) | Journal of the American Academy of Dermatology | 2015 | 498 |
| 31 | Agalsidase-Beta Therapy for Advanced Fabry Disease | Annals of Internal Medicine | 2007 | 493 |
| 32 | Frontotemporal dementia | Lancet Neurology, The | 2005 | 492 |
| 33 | Characteristics of Secondary, Primary, and Compensated Hypogonadism in Aging Men: Evidence from the European Male Ageing Study | Journal of Clinical Endocrinology and Metabolism | 2010 | 481 |
| 34 | Does anaesthesia cause postoperative cognitive dysfunction? A randomised study of regional versus general anaesthesia in 438 elderly patients | Acta Anaesthesiologica Scandinavica | 2003 | 479 |
| 35 | The cortical topography of human swallowing musculature in health and disease | Nature Medicine | 1996 | 477 |
| 36 | Microscopic activity in ulcerative colitis: what does it mean? | Gut | 1991 | 475 |
| 37 | ESPEN endorsed recommendations. Definition and classification of intestinal failure in adults | Clinical Nutrition | 2015 | 473 |
| 38 | Experience-based learning: a model linking the processes and outcomes of medical students' workplace learning | Medical Education | 2007 | 455 |
| 39 | Guidelines for topical photodynamic therapy: report of a workshop of the British Photodermatology Group | British Journal of Dermatology | 2002 | 444 |
| 40 | Predictors of pharmacoresistant epilepsy | Epilepsy Research | 2007 | 444 |
| 41 | Females with Fabry disease frequently have major organ involvement: Lessons from the Fabry Registry | Molecular Genetics and Metabolism | 2008 | 442 |
| 42 | The intestinal epithelial stem cell: the mucosal governor | International Journal of Experimental Pathology | 1997 | 441 |
| 43 | Short Bowel Syndrome and Intestinal Failure: Consensus Definitions and Overview | Clinical Gastroenterology and Hepatology | 2006 | 440 |
| 44 | Post-mortem imaging as an alternative to autopsy in the diagnosis of adult deaths: a validation study | Lancet, The | 2012 | 435 |
| 45 | Long-term reorganization of human motor cortex driven by short-term sensory stimulation | Nature Neuroscience | 1998 | 432 |
| 46 | Recombinant human anti–transforming growth factor β1 antibody therapy in systemic sclerosis: A multicenter, randomized, placebo-controlled phase I/II trial of CAT-192 | Arthritis and Rheumatism | 2007 | 415 |
| 47 | Predicting who develops chronic low back pain in primary care: a prospective study | BMJ: British Medical Journal | 1999 | 413 |
| 48 | British Association of Dermatologists’ guidelines for biologic interventions for psoriasis 2009 | British Journal of Dermatology | 2009 | 412 |
| 49 | A Trial of Two Cognitive-Behavioural Methods of Treating Drug-Resistant Residual Psychotic Symptoms in Schizophrenic Patients: I. Outcome | British Journal of Psychiatry | 1993 | 404 |
| 50 | Nerve growth factor expression and innervation of the painful intervertebral disc | Journal of Pathology | 2002 | 396 |
