| # | Title | Journal | Year | Citations |
|---|
|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,789 |
| 2 | Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 | Intensive Care Medicine | 2017 | 4,786 |
| 3 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,158 |
| 4 | The American Urological Association Symptom Index for Benign Prostatic Hyperplasia | Journal of Urology | 1992 | 3,156 |
| 5 | Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 | Critical Care Medicine | 2017 | 2,414 |
| 6 | Lower Extremity Function and Subsequent Disability: Consistency Across Studies, Predictive Models, and Value of Gait Speed Alone Compared With the Short Physical Performance Battery | Journals of Gerontology - Series A Biological Sciences and Medical Sciences | 2000 | 2,321 |
| 7 | Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing | Nature Genetics | 2019 | 2,145 |
| 8 | Pembrolizumab alone or with chemotherapy versus cetuximab with chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-048): a randomised, open-label, phase 3 study | Lancet, The | 2019 | 2,012 |
| 9 | Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021 | Intensive Care Medicine | 2021 | 1,915 |
| 10 | Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation | Cell | 2018 | 1,552 |
| 11 | Elastic Moduli of Breast and Prostate Tissues under Compression | Ultrasonic Imaging | 1998 | 1,528 |
| 12 | Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study | Lancet, The | 2020 | 1,443 |
| 13 | The CRAPome: a contaminant repository for affinity purification–mass spectrometry data | Nature Methods | 2013 | 1,428 |
| 14 | Practice guideline update summary: Mild cognitive impairment [RETIRED] | Neurology | 2018 | 1,409 |
| 15 | Transurethral Prostatectomy: Immediate and Postoperative Complications. A Cooperative Study of 13 Participating Institutions Evaluating 3,885 Patients | Journal of Urology | 1989 | 1,391 |
| 16 | FtsZ ring structure associated with division in Escherichia coli | Nature | 1991 | 1,374 |
| 17 | Multiple Female Reproductive Failures in Cyclooxygenase 2–Deficient Mice | Cell | 1997 | 1,322 |
| 18 | Pharmacology of oleanolic acid and ursolic acid | Journal of Ethnopharmacology | 1995 | 1,268 |
| 19 | Green tea catechin, epigallocatechin-3-gallate (EGCG): Mechanisms, perspectives and clinical applications | Biochemical Pharmacology | 2011 | 1,249 |
| 20 | The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity | Proceedings of the National Academy of Sciences of the United States of America | 2001 | 1,248 |
| 21 | Consensus Guidelines for the Management of Postoperative Nausea and Vomiting | Anesthesia and Analgesia | 2014 | 1,232 |
| 22 | Association analysis identifies 65 new breast cancer risk loci | Nature | 2017 | 1,182 |
| 23 | Efficacy and safety of rituximab in moderately‐to‐severely active systemic lupus erythematosus: The randomized, double‐blind, phase ii/iii systemic lupus erythematosus evaluation of rituximab trial | Arthritis and Rheumatism | 2010 | 1,150 |
| 24 | Iliac Crest Bone Graft Harvest Donor Site Morbidity | Spine | 1995 | 1,144 |
| 25 | Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021 | Critical Care Medicine | 2021 | 1,140 |
| 26 | Hazards of Hospitalization of the Elderly | Annals of Internal Medicine | 1993 | 1,133 |
| 27 | Sensory Processing in Children With and Without Autism: A Comparative Study Using the Short Sensory Profile | American Journal of Occupational Therapy | 2007 | 1,121 |
| 28 | A simplified method for the analysis of hydroxyproline in biological tissues | Clinical Biochemistry | 1996 | 1,120 |
| 29 | Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME | Archives of Toxicology | 2013 | 1,117 |
| 30 | Physical Performance Measures in the Clinical Setting | Journal of the American Geriatrics Society | 2003 | 1,100 |
| 31 | Claudins and the Modulation of Tight Junction Permeability | Physiological Reviews | 2013 | 1,098 |
| 32 | Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein | Nature | 2011 | 1,089 |
| 33 | Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism | Nature Genetics | 2006 | 1,082 |
| 34 | The Stroke Impact Scale Version 2.0 | Stroke | 1999 | 1,041 |
| 35 | METALLOTHIONEIN: An Intracellular Protein to Protect Against Cadmium Toxicity | Annual Review of Pharmacology and Toxicology | 1999 | 1,020 |
| 36 | Evidence-based guideline update: Determining brain death in adults | Neurology | 2010 | 983 |
| 37 | Functional genomic landscape of acute myeloid leukaemia | Nature | 2018 | 978 |
| 38 | Pain as a global public health priority | BMC Public Health | 2011 | 969 |
| 39 | Glucocorticoid-Induced Osteoporosis: Pathogenesis and Management | Annals of Internal Medicine | 1990 | 949 |
| 40 | Mutations in Kir2.1 Cause the Developmental and Episodic Electrical Phenotypes of Andersen's Syndrome | Cell | 2001 | 937 |
| 41 | The Interferon-Induced Protein BST-2 Restricts HIV-1 Release and Is Downregulated from the Cell Surface by the Viral Vpu Protein | Cell Host and Microbe | 2008 | 932 |
| 42 | Antithrombotic Therapy for Atrial Fibrillation | Chest | 2012 | 897 |
| 43 | 2017 European League Against Rheumatism/American College of Rheumatology classification criteria for adult and juvenile idiopathic inflammatory myopathies and their major subgroups | Annals of the Rheumatic Diseases | 2017 | 845 |
| 44 | Summary of evidence-based guideline update: Evaluation and management of concussion in sports | Neurology | 2013 | 835 |
| 45 | Subthalamic nucleus deep brain stimulation: Summary and meta-analysis of outcomes | Movement Disorders | 2006 | 824 |
| 46 | Hydroxyldaunomycin (adriamycin) combination chemotherapy in malignant lymphoma | Cancer | 1976 | 818 |
| 47 | Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease | Nature Genetics | 2017 | 818 |
| 48 | Mitophagy: mechanisms, pathophysiological roles, and analysis | Biological Chemistry | 2012 | 804 |
| 49 | A Longitudinal Investigation of Reading Outcomes in Children With Language Impairments | Journal of Speech, Language, and Hearing Research | 2002 | 786 |
| 50 | Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients With COVID-19 (April 2020) | Clinical Infectious Diseases | 2024 | 779 |
