| # | Title | Journal | Year | Citations |
|---|
| 1 | Mapping the Mouse Cell Atlas by Microwell-Seq | Cell | 2018 | 1,068 |
| 2 | ceRNA in cancer: possible functions and clinical implications | Journal of Medical Genetics | 2015 | 1,031 |
| 3 | The Chinese Society of Clinical Oncology (CSCO): clinical guidelines for the diagnosis and treatment of gastric cancer | Cancer Communications | 2019 | 418 |
| 4 | Circular Noncoding RNA HIPK3 Mediates Retinal Vascular Dysfunction in Diabetes Mellitus | Circulation | 2017 | 416 |
| 5 | N 6 -methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription | Science | 2020 | 406 |
| 6 | Metal–Organic Framework-Based Sensors for Environmental Contaminant Sensing | Nano-Micro Letters | 2018 | 389 |
| 7 | Liver impairment in COVID‐19 patients: A retrospective analysis of 115 cases from a single centre in Wuhan city, China | Liver International | 2020 | 388 |
| 8 | Characteristics and clinical significance of myocardial injury in patients with severe coronavirus disease 2019 | European Heart Journal | 2020 | 380 |
| 9 | Psychological symptoms among frontline healthcare workers during COVID-19 outbreak in Wuhan | General Hospital Psychiatry | 2020 | 360 |
| 10 | Association between age and clinical characteristics and outcomes of COVID-19 | European Respiratory Journal | 2020 | 316 |
| 11 | Engineered Redox‐Responsive PEG Detachment Mechanism in PEGylated Nano‐Graphene Oxide for Intracellular Drug Delivery | Small | 2012 | 308 |
| 12 | Targeting Negative Surface Charges of Cancer Cells by Multifunctional Nanoprobes | Theranostics | 2016 | 295 |
| 13 | Guiding Principles for Chronic Total Occlusion Percutaneous Coronary Intervention | Circulation | 2019 | 263 |
| 14 | Establishment of porcine and human expanded potential stem cells | Nature Cell Biology | 2019 | 261 |
| 15 | Double Kissing Crush Versus Provisional Stenting for Left Main Distal Bifurcation Lesions | Journal of the American College of Cardiology | 2017 | 256 |
| 16 | Metformin protects against apoptosis and senescence in nucleus pulposus cells and ameliorates disc degeneration in vivo | Cell Death and Disease | 2016 | 240 |
| 17 | Tumor‐Targeted Drug and CpG Delivery System for Phototherapy and Docetaxel‐Enhanced Immunotherapy with Polarization toward M1‐Type Macrophages on Triple Negative Breast Cancers | Advanced Materials | 2019 | 238 |
| 18 | Ultrasmall Cu2-xS nanodots as photothermal-enhanced Fenton nanocatalysts for synergistic tumor therapy at NIR-II biowindow | Biomaterials | 2019 | 223 |
| 19 | Emergence of Indigenous Artemisinin-Resistant Plasmodium falciparum in Africa | New England Journal of Medicine | 2017 | 219 |
| 20 | Cutting Edge: All-Trans Retinoic Acid Sustains the Stability and Function of Natural Regulatory T Cells in an Inflammatory Milieu | Journal of Immunology | 2010 | 205 |
| 21 | Gut microbiome may contribute to insulin resistance and systemic inflammation in obese rodents: a meta-analysis | Physiological Genomics | 2018 | 198 |
| 22 | Multi-organ Site Metastatic Reactivation Mediated by Non-canonical Discoidin Domain Receptor 1 Signaling | Cell | 2016 | 194 |
| 23 | Concise Review: NANOG in Cancer Stem Cells and Tumor Development: An Update and Outstanding Questions | Stem Cells | 2015 | 177 |
| 24 | Angiographic quantitative flow ratio-guided coronary intervention (FAVOR III China): a multicentre, randomised, sham-controlled trial | Lancet, The | 2021 | 175 |
| 25 | Role of Transcription Factor Acetylation in Diabetic Kidney Disease | Diabetes | 2014 | 171 |
| 26 | Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan | Nature Communications | 2019 | 171 |
| 27 | Circular RNA circFGFR1 promotes progression and anti-PD-1 resistance by sponging miR-381-3p in non-small cell lung cancer cells | Molecular Cancer | 2019 | 169 |
| 28 | Integrated Analysis of Genetic Ancestry and Genomic Alterations across Cancers | Cancer Cell | 2018 | 168 |
| 29 | Microfluidic Immunoassays for Sensitive and Simultaneous Detection of IgG/IgM/Antigen of SARS-CoV-2 within 15 min | Analytical Chemistry | 2020 | 167 |
| 30 | Histone deacetylases as targets for treatment of multiple diseases | Clinical Science | 2013 | 166 |
| 31 | Tigliane Diterpenoids from the Euphorbiaceae and Thymelaeaceae Families | Chemical Reviews | 2015 | 160 |
| 32 | A Novel KLF4/LDHA Signaling Pathway Regulates Aerobic Glycolysis in and Progression of Pancreatic Cancer | Clinical Cancer Research | 2014 | 159 |
| 33 | Efficacy and Tolerability of First-Line Cetuximab Plus Leucovorin, Fluorouracil, and Oxaliplatin (FOLFOX-4) Versus FOLFOX-4 in Patients With RAS Wild-Type Metastatic Colorectal Cancer: The Open-Label, Randomized, Phase III TAILOR Trial | Journal of Clinical Oncology | 2018 | 159 |
| 34 | Chinese experts’ consensus on the Internet of Things-aided diagnosis and treatment of coronavirus disease 2019 (COVID-19) | Clinical EHealth | 2020 | 154 |
| 35 | Regulation of STAT signaling by acetylation | Cellular Signalling | 2013 | 152 |
| 36 | CRISPR-Cas9: a new and promising player in gene therapy | Journal of Medical Genetics | 2015 | 150 |
| 37 | Enhancer of Zeste Homolog 2 Inhibition Attenuates Renal Fibrosis by Maintaining Smad7 and Phosphatase and Tensin Homolog Expression | Journal of the American Society of Nephrology: JASN | 2016 | 148 |
| 38 | MiR-21/Smad 7 signaling determines TGF-β1-induced CAF formation | Scientific Reports | 2013 | 146 |
| 39 | In Vitro Expansion of Primary Human Hepatocytes with Efficient Liver Repopulation Capacity | Cell Stem Cell | 2018 | 145 |
| 40 | LncRNA SNHG3 induces EMT and sorafenib resistance by modulating the miR‐128/CD151 pathway in hepatocellular carcinoma | Journal of Cellular Physiology | 2019 | 143 |
| 41 | Approved CAR T cell therapies: ice bucket challenges on glaring safety risks and long-term impacts | Drug Discovery Today | 2018 | 142 |
| 42 | Senescence in Mesenchymal Stem Cells: Functional Alterations, Molecular Mechanisms, and Rejuvenation Strategies | Frontiers in Cell and Developmental Biology | 2020 | 142 |
| 43 | Nanomaterials for Cancer Precision Medicine | Advanced Materials | 2018 | 136 |
| 44 | Genetic or Pharmacologic Blockade of EGFR Inhibits Renal Fibrosis | Journal of the American Society of Nephrology: JASN | 2012 | 135 |
| 45 | Long noncoding RNASNHG1promotes non‐small cell lung cancer progression by up‐regulatingMTDH viasponging miR‐145–5p | FASEB Journal | 2018 | 134 |
| 46 | Induced Foxp3+ regulatory T cells: a potential new weapon to treat autoimmune and inflammatory diseases? | Journal of Molecular Cell Biology | 2012 | 133 |
| 47 | Inhibition of amyloid beta toxicity in zebrafish with a chaperone-gold nanoparticle dual strategy | Nature Communications | 2019 | 132 |
| 48 | New Insights Into the Role and Mechanism of Partial Epithelial-Mesenchymal Transition in Kidney Fibrosis | Frontiers in Physiology | 2020 | 132 |
| 49 | Up‐regulated TLR4 in cardiomyocytes exacerbates heart failure after long‐term myocardial infarction | Journal of Cellular and Molecular Medicine | 2015 | 129 |
| 50 | Photoluminescence and photothermal effect of Fe3O4 nanoparticles for medical imaging and therapy | Applied Physics Letters | 2014 | 128 |
