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Institute for Molecular Medicine Finland
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top-articles
Institute for Molecular Medicine Finland
322
(top 1%)
papers
8.6K
(top 1%)
citations
51
(top 1%)
h
-index
84
(top 1%)
g
-index
370
all documents
10.6K
doc citations
2.1K
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
FINEMAP: efficient variable selection using summary data from genome-wide association studies
Bioinformatics
2016
584
2
SynergyFinder: a web application for analyzing drug combination dose–response matrix data
Bioinformatics
2017
403
3
FTO genotype is associated with phenotypic variability of body mass index
Nature
2012
383
4
Genetics of 35 blood and urine biomarkers in the UK Biobank
Nature Genetics
2021
377
5
Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis
Nature Genetics
2013
339
6
Forty-Three Loci Associated with Plasma Lipoprotein Size, Concentration, and Cholesterol Content in Genome-Wide Analysis
PLoS Genetics
2009
300
7
Polygenic and clinical risk scores and their impact on age at onset and prediction of cardiometabolic diseases and common cancers
Nature Medicine
2020
281
8
Quantitative scoring of differential drug sensitivity for individually optimized anticancer therapies
Scientific Reports
2014
243
9
Functionally informed fine-mapping and polygenic localization of complex trait heritability
Nature Genetics
2020
185
10
Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles
Journal of Extracellular Vesicles
2021
182
11
Metabolomic Profiling of Extracellular Vesicles and Alternative Normalization Methods Reveal Enriched Metabolites and Strategies to Study Prostate Cancer-Related Changes
Theranostics
2017
167
12
metaCCA: summary statistics-based multivariate meta-analysis of genome-wide association studies using canonical correlation analysis
Bioinformatics
2016
138
13
Phenome-wide association studies across large population cohorts support drug target validation
Nature Communications
2018
134
14
Systems pathology by multiplexed immunohistochemistry and whole-slide digital image analysis
Scientific Reports
2017
120
15
Identification of tumor epithelium and stroma in tissue microarrays using texture analysis
Diagnostic Pathology
2012
119
16
Association of tamoxifen resistance and lipid reprogramming in breast cancer
BMC Cancer
2018
113
17
Systematic knockdown of epigenetic enzymes identifies a novel histone demethylase PHF8 overexpressed in prostate cancer with an impact on cell proliferation, migration and invasion
Oncogene
2012
112
18
Mutation Update: The Spectra of Nebulin Variants and Associated Myopathies
Human Mutation
2014
107
19
Quantifying the Impact of Rare and Ultra-rare Coding Variation across the Phenotypic Spectrum
American Journal of Human Genetics
2018
102
20
Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells
Nature
2020
101
21
The role of polygenic risk and susceptibility genes in breast cancer over the course of life
Nature Communications
2020
101
22
A transcriptomics data-driven gene space accurately predicts liver cytopathology and drug-induced liver injury
Nature Communications
2017
99
23
A genome-wide meta-analysis of association studies of Cloninger's Temperament Scales
Translational Psychiatry
2012
98
24
Capturing complex tumour biology in vitro: histological and molecular characterisation of precision cut slices
Scientific Reports
2015
98
25
Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits
PLoS Genetics
2020
95
26
Targeting autophagy by small molecule inhibitors of vacuolar protein sorting 34 (Vps34) improves the sensitivity of breast cancer cells to Sunitinib
Cancer Letters
2018
93
27
A combined analysis of genome-wide association studies in breast cancer
Breast Cancer Research and Treatment
2011
90
28
Assessing allele-specific expression across multiple tissues from RNA-seq read data
Bioinformatics
2015
90
29
Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging
Genome Biology
2021
90
30
Obatoclax, saliphenylhalamide and gemcitabine inhibit Zika virus infection in vitro and differentially affect cellular signaling, transcription and metabolism
Antiviral Research
2017
88
31
Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability
Nature Communications
2021
87
32
Genetic analysis of obstructive sleep apnoea discovers a strong association with cardiometabolic health
European Respiratory Journal
2021
85
33
Somatic mutations in clonally expanded cytotoxic T lymphocytes in patients with newly diagnosed rheumatoid arthritis
Nature Communications
2017
83
34
Obatoclax, Saliphenylhalamide, and Gemcitabine Inhibit Influenza A Virus Infection
Journal of Biological Chemistry
2012
80
35
Genome-wide association study across European and African American ancestries identifies a SNP in DNMT3B contributing to nicotine dependence
Molecular Psychiatry
2018
80
36
Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits
Nature Communications
2020
80
37
The transcription factor Sox11 is a prognostic factor for improved recurrence-free survival in epithelial ovarian cancer
European Journal of Cancer
2009
79
38
Cancer stem cell drugs target K-ras signaling in a stemness context
Oncogene
2016
78
39
A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity
Human Molecular Genetics
2019
76
40
Emerging cellular targets for influenza antiviral agents
Trends in Pharmacological Sciences
2012
75
41
Discovery of novel drug sensitivities in T-PLL by high-throughput ex vivo drug testing and mutation profiling
Leukemia
2018
75
42
Whole genome association scan for genetic polymorphisms influencing information processing speed
Biological Psychology
2011
70
43
Leveraging European infrastructures to access 1 million human genomes by 2022
Nature Reviews Genetics
2019
69
44
Patient-Derived Organoids from Multiple Colorectal Cancer Liver Metastases Reveal Moderate Intra-patient Pharmacotranscriptomic Heterogeneity
Clinical Cancer Research
2020
68
45
Leveraging multi-way interactions for systematic prediction of pre-clinical drug combination effects
Nature Communications
2020
63
46
Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci
Nature Communications
2022
63
47
Clonal hematopoiesis in patients with rheumatoid arthritis
Blood Cancer Journal
2018
62
48
Analysis of Detailed Phenotype Profiles Reveals CHRNA5-CHRNA3-CHRNB4 Gene Cluster Association With Several Nicotine Dependence Traits
Nicotine and Tobacco Research
2012
61
49
A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis
European Journal of Human Genetics
2010
60
50
Whole-genome view of the consequences of a population bottleneck using 2926 genome sequences from Finland and United Kingdom
European Journal of Human Genetics
2017
60
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