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Top Articles

#TitleJournalYearCitations
1Type I interferon is selectively required by dendritic cells for immune rejection of tumorsJournal of Experimental Medicine2011874
2Intestinal Tolerance Requires Gut Homing and Expansion of FoxP3+ Regulatory T Cells in the Lamina PropriaImmunity2011757
3De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cellsNature Medicine2014694
4EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapyNature Medicine2011631
5Regulation of antiviral T cell responses by type I interferonsNature Reviews Immunology2015371
6Metabolic pathways in T cell activation and lineage differentiationSeminars in Immunology2016361
7A Lymphotoxin-Driven Pathway to Hepatocellular CarcinomaCancer Cell2009345
8Foxp3+ T cells expressing RORγt represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammationMucosal Immunology2016341
9Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculatureBlood2013300
10IL-7 Engages Multiple Mechanisms to Overcome Chronic Viral Infection and Limit Organ PathologyCell2011281
11Etomoxir Actions on Regulatory and Memory T Cells Are Independent of Cpt1a-Mediated Fatty Acid OxidationCell Metabolism2018264
12Host-cell sensors for Plasmodium activate innate immunity against liver-stage infectionNature Medicine2014256
13The green tea polyphenol, epigallocatechin-3-gallate, inhibits hepatitis C virus entryHepatology2011255
14Tolerance Rather Than Immunity Protects From Helicobacter pylori–Induced Gastric PreneoplasiaGastroenterology2011250
15Etomoxir Inhibits Macrophage Polarization by Disrupting CoA HomeostasisCell Metabolism2018242
16Neuropilin 1 deficiency on CD4+Foxp3+ regulatory T cells impairs mouse melanoma growthJournal of Experimental Medicine2012222
17Maturation of Lymph Node Fibroblastic Reticular Cells from Myofibroblastic Precursors Is Critical for Antiviral ImmunityImmunity2013219
18Type I Interferons Protect T Cells against NK Cell Attack Mediated by the Activating Receptor NCR1Immunity2014199
19Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replicationPLoS Pathogens2017184
20Quantitative image analysis of microbial communities with BiofilmQNature Microbiology2021181
21Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiationNature Immunology2011179
22cGAS Senses Human Cytomegalovirus and Induces Type I Interferon Responses in Human Monocyte-Derived CellsPLoS Pathogens2016168
23Selective and efficient generation of functional Batf3-dependent CD103+ dendritic cells from mouse bone marrowBlood2014167
24pH-degradable imidazoquinoline-ligated nanogels for lymph node-focused immune activationProceedings of the National Academy of Sciences of the United States of America2016164
25IL-17–induced CXCL12 recruits B cells and induces follicle formation in BALT in the absence of differentiated FDCsJournal of Experimental Medicine2014159
26Regulatory T cells expressing granzyme B play a critical role in controlling lung inflammation during acute viral infectionMucosal Immunology2012156
27Foxp3+ T Cells Induce Perforin-Dependent Dendritic Cell Death in Tumor-Draining Lymph NodesImmunity2010152
28The oral administration of bacterial extracts prevents asthma via the recruitment of regulatory T cells to the airwaysMucosal Immunology2011144
29Brain Endothelial- and Epithelial-Specific Interferon Receptor Chain 1 Drives Virus-Induced Sickness Behavior and Cognitive ImpairmentImmunity2016143
30Microbiota-Induced Type I Interferons Instruct a Poised Basal State of Dendritic CellsCell2020139
31Regulatory T Cells Increase the Avidity of Primary CD8 + T Cell Responses and Promote MemoryScience2012138
32Sialic acid-modified antigens impose tolerance via inhibition of T-cell proliferation and de novo induction of regulatory T cellsProceedings of the National Academy of Sciences of the United States of America2016135
33MicroRNA-221 overexpression accelerates hepatocyte proliferation during liver regenerationHepatology2013132
34The regulatory T-cell response during acute retroviral infection is locally defined and controls the magnitude and duration of the virus-specific cytotoxic T-cell responseBlood2009130
35Hookworm recombinant protein promotes regulatory T cell responses that suppress experimental asthmaScience Translational Medicine2016123
36RIG-I/MAVS and STING signaling promote gut integrity during irradiation- and immune-mediated tissue injuryScience Translational Medicine2017114
37Validation of PqsD as an Anti-biofilm Target in Pseudomonas aeruginosa by Development of Small-Molecule InhibitorsJournal of the American Chemical Society2012113
38A Plant-Derived Flavonoid Inhibits Entry of All HCV Genotypes Into Human HepatocytesGastroenterology2012111
39MAP-Kinase Regulated Cytosolic Phospholipase A2 Activity Is Essential for Production of Infectious Hepatitis C Virus ParticlesPLoS Pathogens2012110
40Adaptation of Hepatitis C Virus to Mouse CD81 Permits Infection of Mouse Cells in the Absence of Human Entry FactorsPLoS Pathogens2010109
41Foxp3+ regulatory T cells protect the liver from immune damage and compromise virus control during acute experimental hepatitis B virus infection in miceHepatology2012109
42Cyclosporine A inhibits hepatitis C virus nonstructural protein 2 through cyclophilin AHepatology2009108
43Genomewide Identification of Genetic Determinants of Antimicrobial Drug Resistance in Pseudomonas aeruginosaAntimicrobial Agents and Chemotherapy2009108
44A Highly Immunogenic and Protective Middle East Respiratory Syndrome Coronavirus Vaccine Based on a Recombinant Measles Virus Vaccine PlatformJournal of Virology2015108
45Extra‐hepatic replication and infection of hepatitis E virus in neuronal‐derived cellsJournal of Viral Hepatitis2016104
46Platelet-Derived Growth Factor–Producing CD4+ Foxp3+ Regulatory T Lymphocytes Promote Lung FibrosisAmerican Journal of Respiratory and Critical Care Medicine2011103
47Fatty acid metabolism in CD8+ T cell memory: Challenging current conceptsImmunological Reviews2018103
48Hepatitis C Virus p7 is Critical for Capsid Assembly and EnvelopmentPLoS Pathogens2013102
49Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPRCell2019100
50CD4+ Natural Regulatory T Cells Prevent Experimental Cerebral Malaria via CTLA-4 When Expanded In VivoPLoS Pathogens201098