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Top Articles

#TitleJournalYearCitations
1High expression of PD-L1 in lung cancer may contribute to poor prognosis and tumor cells immune escape through suppressing tumor infiltrating dendritic cells maturationMedical Oncology2011526
2A Comparative Study on the Clinical Features of Coronavirus 2019 (COVID-19) Pneumonia With Other PneumoniasClinical Infectious Diseases2020375
3Genome-wide association study in Chinese men identifies two new prostate cancer risk loci at 9q31.2 and 19q13.4Nature Genetics2012160
4Melatonin activates the Nrf2‐ARE pathway when it protects against early brain injury in a subarachnoid hemorrhage modelJournal of Pineal Research2012146
5Fluorescent Probe-Based Lateral Flow Assay for Multiplex Nucleic Acid DetectionAnalytical Chemistry2014136
6Long noncoding RNA CRNDE promotes colorectal cancer cell proliferation via epigenetically silencing DUSP5/CDKN1A expressionCell Death and Disease2017131
7Telemedicine for detecting diabetic retinopathy: a systematic review and meta-analysisBritish Journal of Ophthalmology2015130
8Increased N6‐methyladenosine causes infertility is associated with FTO expressionJournal of Cellular Physiology2018129
9A novel circular RNA, circFAT1(e2), inhibits gastric cancer progression by targeting miR-548g in the cytoplasm and interacting with YBX1 in the nucleusCancer Letters2019125
10Human Umbilical Cord Mesenchymal Stem Cells Therapy in Cyclophosphamide-Induced Premature Ovarian Failure Rat ModelBioMed Research International2016118
11Effect of human papillomavirus infection on the immune system and its role in the course of cervical cancerOncology Letters2015104
12Exosomes derived from human adipose mesenchymal stem cells improve ovary function of premature ovarian insufficiency by targeting SMADStem Cell Research and Therapy201899
13Anti-inflammatory cytokines in endometriosisCellular and Molecular Life Sciences201999
14FTO mediates LINE1 m 6 A demethylation and chromatin regulation in mESCs and mouse developmentScience202297
15Low-density lipoprotein-coupled N-succinyl chitosan nanoparticles co-delivering siRNA and doxorubicin for hepatocyte-targeted therapyBiomaterials201496
16Cyclic RGD functionalized liposomes encapsulating urokinase for thrombolysisActa Biomaterialia201891
17Long intergenic non-coding RNA 00324 promotes gastric cancer cell proliferation via binding with HuR and stabilizing FAM83B expressionCell Death and Disease201890
18Berberine-induced apoptotic and autophagic death of HepG2 cells requires AMPK activationCancer Cell International201488
19Potential Contribution of Hypoxia-Inducible Factor-1α, Aquaporin-4, and Matrix Metalloproteinase-9 to Blood–Brain Barrier Disruption and Brain Edema After Experimental Subarachnoid HemorrhageJournal of Molecular Neuroscience201285
20Dietary quercetin ameliorates experimental colitis in mouse by remodeling the function of colonic macrophages via a heme oxygenase-1-dependent pathwayCell Cycle201884
21P53 Status as a Predictive Biomarker for Patients Receiving Neoadjuvant Radiation-Based Treatment: A Meta-Analysis in Rectal CancerPLoS ONE201283
22Long noncoding RNA HOXA-AS2 represses P21 and KLF2 expression transcription by binding with EZH2, LSD1 in colorectal cancerOncogenesis201783
23The long intergenic non-protein coding RNA 707 promotes proliferation and metastasis of gastric cancer by interacting with mRNA stabilizing protein HuRCancer Letters201982
24Long non-coding RNA Taurine upregulated gene 1 promotes osteosarcoma cell metastasis by mediating HIF-1α via miR-143-5pCell Death and Disease201977
25Melatonin restricts the viability and angiogenesis of vascular endothelial cells by suppressing HIF-1α/ROS/VEGFInternational Journal of Molecular Medicine201976
26Hsa_circ_101555 functions as a competing endogenous RNA of miR-597-5p to promote colorectal cancer progressionOncogene201976
27Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancerJournal of Experimental and Clinical Cancer Research202176
28Trichomonas vaginalis infection-associated risk of cervical cancer: A meta-analysisEuropean Journal of Obstetrics, Gynecology and Reproductive Biology201875
29Evaluation of prostate cancer antigen 3 for detecting prostate cancer: a systematic review and meta-analysisScientific Reports201674
30Characterization of Metabolic Patterns in Mouse Oocytes during Meiotic MaturationMolecular Cell202074
31Exosomal miRNA-17-5p derived from human umbilical cord mesenchymal stem cells improves ovarian function in premature ovarian insufficiency by regulating SIRT7Stem Cells202074
32Factors Associated With Prolonged Viral Shedding in Patients With Avian Influenza A(H7N9) Virus InfectionJournal of Infectious Diseases201872
33Human amniotic mesenchymal stem cells improve ovarian function in natural aging through secreting hepatocyte growth factor and epidermal growth factorStem Cell Research and Therapy201871
34Nanoscale extracellular vesicle-derived DNA is superior to circulating cell-free DNA for mutation detection in early-stage non-small-cell lung cancerAnnals of Oncology201871
35A novel Germline mutation in HOXB13 is associated with prostate cancer risk in Chinese menProstate201370
36Oocyte competence is maintained by m6A methyltransferase KIAA1429-mediated RNA metabolism during mouse follicular developmentCell Death and Differentiation202070
37METTL3-mediated m6A is required for murine oocyte maturation and maternal-to-zygotic transitionCell Cycle202069
38Janus Gold Triangle-Mesoporous Silica Nanoplatforms for Hypoxia-Activated Radio-Chemo-Photothermal Therapy of Liver CancerACS Applied Materials & Interfaces201968
39Cyclooxygenase-2 in EndometriosisInternational Journal of Biological Sciences201965
40MicroRNA-375 targets PDK1 in pancreatic carcinoma and suppresses cell growth through the Akt signaling pathwayInternational Journal of Molecular Medicine201464
41Bi-allelic Mutations in TTC29 Cause Male Subfertility with Asthenoteratospermia in Humans and MiceAmerican Journal of Human Genetics201962
42Biomaterial-supported MSC transplantation enhances cell–cell communication for spinal cord injuryStem Cell Research and Therapy202161
43Magnesium isoglycyrrhizinate suppresses LPS-induced inflammation and oxidative stress through inhibiting NF-κB and MAPK pathways in RAW264.7 cellsBioorganic and Medicinal Chemistry201960
44Prevalence and incidence rates of Crohn's disease in mainland China: A meta‐analysis of 55 years of researchJournal of Digestive Diseases201059
45Novel circulating microRNAs expression profile in colon cancer: a pilot studyEuropean Journal of Medical Research201758
46Core-Shell Magnetic Gold Nanoparticles for Magnetic Field-Enhanced Radio-Photothermal Therapy in Cervical CancerNanomaterials201757
47Classic chordoma coexisting with benign notochordal cell rest demonstrating different immunohistological expression patterns of brachyury and galectin-3Journal of Clinical Neuroscience201155
48Melatonin alleviates lipopolysaccharide-compromised integrity of blood-brain barrier through activating AMP-activated protein kinase in old miceAging Cell201755
49Disruption of the Circadian Clock Alters Antioxidative Defense via the SIRT1-BMAL1 Pathway in 6-OHDA-Induced Models of Parkinson’s DiseaseOxidative Medicine and Cellular Longevity201854
50MiR-486-5p Serves as a Good Biomarker in Nonsmall Cell Lung Cancer and Suppresses Cell Growth With the Involvement of a Target PIK3R1Frontiers in Genetics201954