| # | Title | Journal | Year | Citations |
|---|
| 1 | Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure | Cell | 2016 | 1,680 |
| 2 | Mapping genomic loci implicates genes and synaptic biology in schizophrenia | Nature | 2022 | 929 |
| 3 | Next-Generation Digital Information Storage in DNA | Science | 2012 | 902 |
| 4 | Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence | Nature Genetics | 2018 | 893 |
| 5 | Accounting for cellular heterogeneity is critical in epigenome-wide association studies | Genome Biology | 2014 | 880 |
| 6 | Common genetic variants influence human subcortical brain structures | Nature | 2015 | 772 |
| 7 | Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain | Nature Neuroscience | 2014 | 663 |
| 8 | Comprehensive functional genomic resource and integrative model for the human brain | Science | 2018 | 618 |
| 9 | Neuronal activity modifies the DNA methylation landscape in the adult brain | Nature Neuroscience | 2011 | 601 |
| 10 | Integrative functional genomic analysis of human brain development and neuropsychiatric risks | Science | 2018 | 516 |
| 11 | Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function | Nature Communications | 2018 | 484 |
| 12 | The genetic architecture of the human cerebral cortex | Science | 2020 | 450 |
| 13 | Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex | Nature Neuroscience | 2021 | 418 |
| 14 | Mapping DNA methylation across development, genotype and schizophrenia in the human frontal cortex | Nature Neuroscience | 2016 | 417 |
| 15 | Altering the course of schizophrenia: progress and perspectives | Nature Reviews Drug Discovery | 2016 | 410 |
| 16 | The PsychENCODE project | Nature Neuroscience | 2015 | 371 |
| 17 | Pausing of RNA Polymerase II Disrupts DNA-Specified Nucleosome Organization to Enable Precise Gene Regulation | Cell | 2010 | 369 |
| 18 | Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis | Nature Neuroscience | 2018 | 300 |
| 19 | Polyester: simulating RNA-seq datasets with differential transcript expression | Bioinformatics | 2015 | 250 |
| 20 | Novel genetic loci associated with hippocampal volume | Nature Communications | 2017 | 250 |
| 21 | Modeling a Genetic Risk for Schizophrenia in iPSCs and Mice Reveals Neural Stem Cell Deficits Associated with Adherens Junctions and Polarity | Cell Stem Cell | 2014 | 238 |
| 22 | Convergence of placenta biology and genetic risk for schizophrenia | Nature Medicine | 2018 | 214 |
| 23 | Novel genetic loci underlying human intracranial volume identified through genome-wide association | Nature Neuroscience | 2016 | 213 |
| 24 | Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network | Science | 2017 | 206 |
| 25 | Neuropsychological mechanism underlying antidepressant effect: a systematic meta-analysis | Molecular Psychiatry | 2015 | 204 |
| 26 | A Bayesian framework for multiple trait colocalization from summary association statistics | Bioinformatics | 2018 | 203 |
| 27 | GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium | Molecular Psychiatry | 2017 | 194 |
| 28 | Molecular and cellular reorganization of neural circuits in the human lineage | Science | 2017 | 192 |
| 29 | Genetic architecture of subcortical brain structures in 38,851 individuals | Nature Genetics | 2019 | 192 |
| 30 | Cultural differences in human brain activity: A quantitative meta-analysis | NeuroImage | 2014 | 187 |
| 31 | Effects of psilocybin on hippocampal neurogenesis and extinction of trace fear conditioning | Experimental Brain Research | 2013 | 179 |
| 32 | Sex differences in glutamate receptor gene expression in major depression and suicide | Molecular Psychiatry | 2015 | 171 |
| 33 | Dynamic regulation of RNA editing in human brain development and disease | Nature Neuroscience | 2016 | 165 |
| 34 | FKBP5 and emotional neglect interact to predict individual differences in amygdala reactivity | Genes, Brain and Behavior | 2012 | 161 |
| 35 | Regional Heterogeneity in Gene Expression, Regulation, and Coherence in the Frontal Cortex and Hippocampus across Development and Schizophrenia | Neuron | 2019 | 158 |
| 36 | BDNF at the synapse: why location matters | Molecular Psychiatry | 2017 | 157 |
| 37 | APOE2 enhances neuroprotection against Alzheimer’s disease through multiple molecular mechanisms | Molecular Psychiatry | 2014 | 156 |
| 38 | Finding the Elusive Psychiatric “Lesion” With 21st-Century Neuroanatomy: A Note of Caution | American Journal of Psychiatry | 2016 | 156 |
| 39 | Association of DNA Methylation Differences With Schizophrenia in an Epigenome-Wide Association Study | JAMA Psychiatry | 2016 | 151 |
| 40 | Developmental regulation of human cortex transcription and its clinical relevance at single base resolution | Nature Neuroscience | 2015 | 142 |
| 41 | A human-specific AS3MT isoform and BORCS7 are molecular risk factors in the 10q24.32 schizophrenia-associated locus | Nature Medicine | 2016 | 142 |
| 42 | Epigenomic Comparison Reveals Activation of “Seed” Enhancers during Transition from Naive to Primed Pluripotency | Cell Stem Cell | 2014 | 137 |
| 43 | Myelin, myelin-related disorders, and psychosis | Schizophrenia Research | 2015 | 124 |
| 44 | Paternal sperm DNA methylation associated with early signs of autism risk in an autism-enriched cohort | International Journal of Epidemiology | 2015 | 121 |
| 45 | Role of activity-dependent BDNF expression in hippocampal–prefrontal cortical regulation of behavioral perseverance | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 116 |
| 46 | Molecular landscapes of human hippocampal immature neurons across lifespan | Nature | 2022 | 116 |
| 47 | SIRT3 mediates hippocampal synaptic adaptations to intermittent fasting and ameliorates deficits in APP mutant mice | Nature Communications | 2019 | 114 |
| 48 | 7q11.23 dosage-dependent dysregulation in human pluripotent stem cells affects transcriptional programs in disease-relevant lineages | Nature Genetics | 2015 | 108 |
| 49 | Functional Role of BDNF Production from Unique Promoters in Aggression and Serotonin Signaling | Neuropsychopharmacology | 2016 | 108 |
| 50 | Altered gene expression in the dorsolateral prefrontal cortex of individuals with schizophrenia | Molecular Psychiatry | 2014 | 105 |
