| # | Title | Journal | Year | Citations |
|---|
| 1 | Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phase 2 trial | Lancet Oncology, The | 2012 | 1,879 |
| 2 | ESMO Consensus Guidelines for management of patients with colon and rectal cancer. A personalized approach to clinical decision making | Annals of Oncology | 2012 | 1,233 |
| 3 | Metastatic colorectal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up | Annals of Oncology | 2014 | 910 |
| 4 | Early colon cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up | Annals of Oncology | 2013 | 874 |
| 5 | Rectal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up | Annals of Oncology | 2013 | 833 |
| 6 | Gastric cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up | Annals of Oncology | 2010 | 737 |
| 7 | 5-year analysis of neoadjuvant pertuzumab and trastuzumab in patients with locally advanced, inflammatory, or early-stage HER2-positive breast cancer (NeoSphere): a multicentre, open-label, phase 2 randomised trial | Lancet Oncology, The | 2016 | 623 |
| 8 | Properties of Resveratrol:In VitroandIn VivoStudies about Metabolism, Bioavailability, and Biological Effects in Animal Models and Humans | Oxidative Medicine and Cellular Longevity | 2015 | 510 |
| 9 | An open access database for the evaluation of heart sound algorithms | Physiological Measurement | 2016 | 473 |
| 10 | Advanced colorectal cancer: ESMO Clinical Practice Guidelines for treatment | Annals of Oncology | 2010 | 384 |
| 11 | Genome-wide parent-of-origin DNA methylation analysis reveals the intricacies of human imprinting and suggests a germline methylation-independent mechanism of establishment | Genome Research | 2014 | 311 |
| 12 | Single-cell transcriptomic atlas of the human endometrium during the menstrual cycle | Nature Medicine | 2020 | 287 |
| 13 | Primary colon cancer: ESMO Clinical Practice Guidelines for diagnosis, adjuvant treatment and follow-up | Annals of Oncology | 2010 | 275 |
| 14 | The Burden of Cardiovascular Diseases Among US States, 1990-2016 | JAMA Cardiology | 2018 | 271 |
| 15 | Gastric cancer: ESMO–ESSO–ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up | Annals of Oncology | 2013 | 250 |
| 16 | Anal cancer: ESMO-ESSO-ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up | Annals of Oncology | 2014 | 244 |
| 17 | Anal cancer: ESMO-ESSO-ESTRO clinical practice guidelines for diagnosis, treatment and follow-up | European Journal of Surgical Oncology | 2014 | 237 |
| 18 | Oesophageal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up | Annals of Oncology | 2013 | 194 |
| 19 | Making sense of big data in health research: Towards an EU action plan | Genome Medicine | 2016 | 190 |
| 20 | Sarcopenia, frailty and their prevention by exercise | Free Radical Biology and Medicine | 2019 | 186 |
| 21 | Anal cancer: ESMO–ESSO–ESTRO clinical practice guidelines for diagnosis, treatment and follow-up | Radiotherapy and Oncology | 2014 | 179 |
| 22 | Molecular Evidence for the Inverse Comorbidity between Central Nervous System Disorders and Cancers Detected by Transcriptomic Meta-analyses | PLoS Genetics | 2014 | 165 |
| 23 | Safety and Efficacy of Low Blood Pressures Among Patients With Diabetes | Journal of the American College of Cardiology | 2012 | 164 |
| 24 | The Mediterranean diet improves the systemic lipid and DNA oxidative damage in metabolic syndrome individuals. A randomized, controlled, trial | Clinical Nutrition | 2013 | 164 |
| 25 | Gastric cancer: ESMO–ESSO–ESTRO clinical practice guidelines for diagnosis, treatment and follow-up | European Journal of Surgical Oncology | 2014 | 162 |
| 26 | Low Lymphocyte Count and Cardiovascular Diseases | Current Medicinal Chemistry | 2011 | 160 |
| 27 | The COVID-19 vaccines rush: participatory community engagement matters more than ever | Lancet, The | 2021 | 156 |
| 28 | Reconstruction of Endometrium from Human Endometrial Side Population Cell Lines | PLoS ONE | 2011 | 154 |
| 29 | Menstruation: science and society | American Journal of Obstetrics and Gynecology | 2020 | 149 |
| 30 | Preimplantation genetic screening using fluorescence in situ hybridization in patients with repetitive implantation failure and advanced maternal age: two randomized trials | Fertility and Sterility | 2013 | 138 |
| 31 | Relevance of Oxygen Concentration in Stem Cell Culture for Regenerative Medicine | International Journal of Molecular Sciences | 2019 | 138 |
| 32 | Familial risk-colorectal cancer: ESMO Clinical Practice Guidelines | Annals of Oncology | 2013 | 136 |
| 33 | Phase I Pharmacokinetic/Pharmacodynamic Study of MLN8237, an Investigational, Oral, Selective Aurora A Kinase Inhibitor, in Patients with Advanced Solid Tumors | Clinical Cancer Research | 2012 | 132 |
| 34 | Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism | Gut | 2017 | 125 |
| 35 | Amyloid-β Toxicity and Tau Hyperphosphorylation are Linked Via RCAN1 in Alzheimer's Disease | Journal of Alzheimer's Disease | 2011 | 121 |
| 36 | Long-Term Potassium Monitoring and Dynamics in Heart Failure and Risk of Mortality | Circulation | 2018 | 121 |
| 37 | Esophageal cancer: Clinical Practice Guidelines for diagnosis, treatment and follow-up | Annals of Oncology | 2010 | 117 |
| 38 | Lipid peroxidation as measured by chromatographic determination of malondialdehyde. Human plasma reference values in health and disease | Archives of Biochemistry and Biophysics | 2021 | 117 |
| 39 | Endometrial microbiota composition is associated with reproductive outcome in infertile patients | Microbiome | 2022 | 113 |
| 40 | Frailty and multimorbidity: Two related yet different concepts | Maturitas | 2017 | 107 |
| 41 | The dapagliflozin and prevention of adverse outcomes in chronic kidney disease (DAPA-CKD) trial: baseline characteristics | Nephrology Dialysis Transplantation | 2020 | 107 |
| 42 | Inverse cancer comorbidity: a serendipitous opportunity to gain insight into CNS disorders | Nature Reviews Neuroscience | 2013 | 106 |
| 43 | Identification and characterization of the human leiomyoma side population as putative tumor-initiating cells | Fertility and Sterility | 2012 | 101 |
| 44 | Balixafortide plus eribulin in HER2-negative metastatic breast cancer: a phase 1, single-arm, dose-escalation trial | Lancet Oncology, The | 2018 | 98 |
| 45 | Functional remediation in bipolar disorder: 1-year follow-up of neurocognitive and functional outcome | British Journal of Psychiatry | 2016 | 95 |
| 46 | Prognostic Value of Strain by Tissue Tracking Cardiac Magnetic Resonance After ST-Segment Elevation Myocardial Infarction | JACC: Cardiovascular Imaging | 2018 | 93 |
| 47 | Carbohydrate Antigen-125–Guided Therapy in Acute Heart Failure | JACC: Heart Failure | 2016 | 88 |
| 48 | Rectal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up | Annals of Oncology | 2010 | 86 |
| 49 | Anal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up | Annals of Oncology | 2010 | 86 |
| 50 | Bone Marrow-Derived Cells from Male Donors Do Not Contribute to the Endometrial Side Population of the Recipient | PLoS ONE | 2012 | 85 |
