| # | Title | Journal | Year | Citations |
|---|
| 1 | Axillary dissection versus no axillary dissection in patients with sentinel-node micrometastases (IBCSG 23–01): a phase 3 randomised controlled trial | Lancet Oncology, The | 2013 | 998 |
| 2 | Long non-coding RNAs and cancer: a new frontier of translational research? | Oncogene | 2012 | 910 |
| 3 | Adjuvant Chemotherapy for Adult Soft Tissue Sarcomas of the Extremities and Girdles: Results of the Italian Randomized Cooperative Trial | Journal of Clinical Oncology | 2001 | 631 |
| 4 | Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer | Nature Genetics | 2013 | 493 |
| 5 | Overexpression of folate binding protein in ovarian cancers | | 1997 | 450 |
| 6 | Integrated mutational and cytogenetic analysis identifies new prognostic subgroups in chronic lymphocytic leukemia | Blood | 2013 | 420 |
| 7 | Association of Type and Location ofBRCA1andBRCA2Mutations With Risk of Breast and Ovarian Cancer | JAMA - Journal of the American Medical Association | 2015 | 390 |
| 8 | Carboplatin plus paclitaxel once a week versus every 3 weeks in patients with advanced ovarian cancer (MITO-7): a randomised, multicentre, open-label, phase 3 trial | Lancet Oncology, The | 2014 | 327 |
| 9 | HIV-associated lymphomas and gamma-herpesviruses | Blood | 2009 | 317 |
| 10 | Family history and the risk of stomach and colorectal cancer | Cancer | 1992 | 308 |
| 11 | Clinical impact of small TP53 mutated subclones in chronic lymphocytic leukemia | Blood | 2014 | 302 |
| 12 | The Prognostic Value of TP53 Mutations in Chronic Lymphocytic Leukemia Is Independent of Del17p13: Implications for Overall Survival and Chemorefractoriness | Clinical Cancer Research | 2009 | 284 |
| 13 | The biology of cancer testis antigens: Putative function, regulation and therapeutic potential | Molecular Oncology | 2011 | 281 |
| 14 | Microsatellite Instability and High Content of Activated Cytotoxic Lymphocytes Identify Colon Cancer Patients with a Favorable Prognosis | American Journal of Pathology | 2001 | 275 |
| 15 | Breast carcinoma during pregnancy | Cancer | 2006 | 269 |
| 16 | Loss and/or formation of antioxidants during food processing and storage | Cancer Letters | 1997 | 260 |
| 17 | Hepatitis C Virus and Risk of Lymphoma and Other Lymphoid Neoplasms: A Meta-analysis of Epidemiologic Studies | Cancer Epidemiology Biomarkers and Prevention | 2006 | 253 |
| 18 | Structural and functional features of the .alpha.3 chain indicate a bridging role for chicken collagen VI in connective tissues | Biochemistry | 1990 | 245 |
| 19 | Risk factors for thyroid cancer: an epidemiological review focused on nutritional factors | Cancer Causes and Control | 2009 | 245 |
| 20 | Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk | PLoS Genetics | 2013 | 244 |
| 21 | The classical Hodgkin's lymphoma microenvironment and its role in promoting tumour growth and immune escape | Journal of Pathology | 2010 | 231 |
| 22 | Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention | Oncotarget | 2014 | 231 |
| 23 | Relevance of CD49d protein expression as overall survival and progressive disease prognosticator in chronic lymphocytic leukemia | Blood | 2008 | 226 |
| 24 | Combined effect of tobacco and alcohol on laryngeal cancer risk: a case-control study | Cancer Causes and Control | 2002 | 225 |
| 25 | AIDS-related lymphomas: from pathogenesis to pathology | British Journal of Haematology | 2005 | 220 |
| 26 | Gene Expression Analysis of Angioimmunoblastic Lymphoma Indicates Derivation from T Follicular Helper Cells and Vascular Endothelial Growth Factor Deregulation | Cancer Research | 2007 | 220 |
| 27 | Predictive Role of the UGT1A1, UGT1A7, and UGT1A9 Genetic Variants and Their Haplotypes on the Outcome of Metastatic Colorectal Cancer Patients Treated With Fluorouracil, Leucovorin, and Irinotecan | Journal of Clinical Oncology | 2009 | 216 |
| 28 | Evidence of a founder mutation of BRCA1 in a highly homogeneous population from southern Italy with breast/ovarian cancer | Human Mutation | 2001 | 215 |
| 29 | Comparison of cancers of the oral cavity and pharynx worldwide: etiological clues | Oral Oncology | 2000 | 210 |
| 30 | Preoperative hyperfractionated chemoradiation for locally recurrent rectal cancer in patients previously irradiated to the pelvis: A multicentric phase II study | International Journal of Radiation Oncology Biology Physics | 2006 | 209 |
| 31 | Two main genetic pathways lead to the transformation of chronic lymphocytic leukemia to Richter syndrome | Blood | 2013 | 208 |
| 32 | Biological and clinical risk factors of chronic lymphocytic leukaemia transformation to Richter syndrome | British Journal of Haematology | 2008 | 206 |
| 33 | Molecular prediction of durable remission after first-line fludarabine-cyclophosphamide-rituximab in chronic lymphocytic leukemia | Blood | 2015 | 197 |
| 34 | Kaposi's sarcoma‐associated herpesvirus DNA sequences in AIDS‐related and AIDS‐unrelated lymphomatous effusions | British Journal of Haematology | 1996 | 187 |
| 35 | Validation of a multidimensional evaluation scale for use in elderly cancer patients | | 1996 | 181 |
| 36 | Type A Modules: Interacting Domains Found in Several Non-Fibrillar Collagens and in Other Extracellular Matrix Proteins | Matrix Biology | 1993 | 178 |
| 37 | The impact of obesity and diabetes mellitus on the risk of hepatocellular carcinoma | Annals of Oncology | 2009 | 173 |
| 38 | Genome-wide DNA profiling of marginal zone lymphomas identifies subtype-specific lesions with an impact on the clinical outcome | Blood | 2011 | 173 |
| 39 | Sequential cytoplasmic calcium signals in a 2-stage platelet activation process induced by the glycoprotein Ibα mechanoreceptor | Blood | 2002 | 172 |
| 40 | Endoglin: An accessory component of the TGF-?-binding receptor-complex with diagnostic, prognostic, and bioimmunotherapeutic potential in human malignancies | Journal of Cellular Physiology | 2001 | 162 |
| 41 | Oral hygiene, dentition, sexual habits and risk of oral cancer | British Journal of Cancer | 2000 | 161 |
| 42 | A pooled analysis of case-control studies of thyroid cancer: cigarette smoking and consumption of alcohol, coffee, and tea | Cancer Causes and Control | 2003 | 156 |
| 43 | B-cell non-Hodgkin's lymphoma and hepatitis C virus infection: A systematic review | International Journal of Cancer | 2004 | 155 |
| 44 | Stathmin: a protein with many tasks. New biomarker and potential target in cancer | Expert Opinion on Therapeutic Targets | 2011 | 155 |
| 45 | A pooled analysis of case-control studies of thyroid cancer. IV. Benign thyroid diseases | Cancer Causes and Control | 1999 | 154 |
| 46 | CD38/CD31, the CCL3 and CCL4 Chemokines, and CD49d/Vascular Cell Adhesion Molecule-1 Are Interchained by Sequential Events Sustaining Chronic Lymphocytic Leukemia Cell Survival | Cancer Research | 2009 | 153 |
| 47 | KSHV/HHV8‐associated lymphomas | British Journal of Haematology | 2008 | 152 |
| 48 | Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus Type 8-Positive Solid Lymphomas | Journal of Molecular Diagnostics | 2005 | 146 |
| 49 | Influence of food groups and food diversity on breast cancer risk in Italy | International Journal of Cancer | 1995 | 145 |
| 50 | p53 over-expression is an early event in the development of human squamous-cell carcinoma of the larynx: Genetic and prognostic implications | International Journal of Cancer | 1992 | 143 |
