| # | Title | Journal | Year | Citations |
|---|
| 1 | Genome-wide association study identifies susceptibility loci for IgA nephropathy | Nature Genetics | 2011 | 528 |
| 2 | Clinical characteristics and risk factors associated with COVID-19 severity in patients with haematological malignancies in Italy: a retrospective, multicentre, cohort study | Lancet Haematology,the | 2020 | 430 |
| 3 | Successful Validation of the Palliative Prognostic Score in Terminally Ill Cancer Patients | Journal of Pain and Symptom Management | 1999 | 365 |
| 4 | Efficacy and safety of colchicine for treatment of multiple recurrences of pericarditis (CORP-2): a multicentre, double-blind, placebo-controlled, randomised trial | Lancet, The | 2014 | 286 |
| 5 | Colchicine for Prevention of Postpericardiotomy Syndrome and Postoperative Atrial Fibrillation | JAMA - Journal of the American Medical Association | 2014 | 258 |
| 6 | Hemofiltration and Hemodiafiltration Reduce Intradialytic Hypotension in ESRD | Journal of the American Society of Nephrology: JASN | 2010 | 239 |
| 7 | COlchicine for the Prevention of the Post-pericardiotomy Syndrome (COPPS): a multicentre, randomized, double-blind, placebo-controlled trial | European Heart Journal | 2010 | 221 |
| 8 | Baseline Findings of the Italian Multicenter Randomized Controlled Trial of "Once-Only Sigmoidoscopy"--SCORE | Journal of the National Cancer Institute | 2002 | 206 |
| 9 | Prevalence, incidence and types of mild anemia in the elderly: the "Health and Anemia" population-based study | Haematologica | 2010 | 183 |
| 10 | Randomized Trial of Different Screening Strategies for Colorectal Cancer: Patient Response and Detection Rates | Journal of the National Cancer Institute | 2005 | 178 |
| 11 | Risk associated with pregnancy in hypertrophic cardiomyopathy | Journal of the American College of Cardiology | 2002 | 174 |
| 12 | Management strategies in patients affected by chronic total occlusions: results from the Italian Registry of Chronic Total Occlusions | European Heart Journal | 2015 | 161 |
| 13 | A MALT lymphoma prognostic index | Blood | 2017 | 149 |
| 14 | ROBUST: A Phase III Study of Lenalidomide Plus R-CHOP Versus Placebo Plus R-CHOP in Previously Untreated Patients With ABC-Type Diffuse Large B-Cell Lymphoma | Journal of Clinical Oncology | 2021 | 132 |
| 15 | Infective Endocarditis in Hypertrophic Cardiomyopathy | Circulation | 1999 | 125 |
| 16 | Association of Mild Anemia with Cognitive, Functional, Mood and Quality of Life Outcomes in the Elderly: The “Health and Anemia” Study | PLoS ONE | 2008 | 124 |
| 17 | The influence of gender on the epidemiology of and outcome from severe sepsis | Critical Care | 2013 | 124 |
| 18 | Systematic versus on-demand early palliative care: A randomised clinical trial assessing quality of care and treatment aggressiveness near the end of life | European Journal of Cancer | 2016 | 121 |
| 19 | Association of mild anemia with hospitalization and mortality in the elderly: the Health and Anemia population-based study | Haematologica | 2009 | 114 |
| 20 | Ostial and midshaft lesions vs. bifurcation lesions in 1111 patients with unprotected left main coronary artery stenosis treated with drug-eluting stents: results of the survey from the Italian Society of Invasive Cardiology | European Heart Journal | 2009 | 112 |
| 21 | A randomized trial of intensive versus minimal surveillance of patients with resected Dukes B2-C colorectal carcinoma | Annals of Oncology | 2016 | 111 |
| 22 | Contemporary Features, Risk Factors, and Prognosis of the Post-Pericardiotomy Syndrome | American Journal of Cardiology | 2011 | 106 |
| 23 | Rituximab, bendamustine, and low-dose cytarabine as induction therapy in elderly patients with mantle cell lymphoma: a multicentre, phase 2 trial from Fondazione Italiana Linfomi | Lancet Haematology,the | 2017 | 106 |
| 24 | Histologic transformation in marginal zone lymphomas | Annals of Oncology | 2015 | 104 |
| 25 | Transradial Versus Transfemoral Intervention for Acute Myocardial Infarction | JACC: Cardiovascular Interventions | 2012 | 101 |
| 26 | Final results of a multicenter phase II clinical trial evaluating the activity of single-agent lapatinib in patients with HER2-negative metastatic breast cancer and HER2-positive circulating tumor cells. A proof-of-concept study | Breast Cancer Research and Treatment | 2012 | 101 |
| 27 | Tumor-infiltrating lymphocytes (TILs) are a powerful prognostic marker in patients with triple-negative breast cancer enrolled in the IBCSG phase III randomized clinical trial 22-00 | Breast Cancer Research and Treatment | 2016 | 100 |
| 28 | Body Fat and Other Metabolic Effects of Atazanavir and Efavirenz, Each Administered in Combination with Zidovudine plus Lamivudine, in Antiretroviral- Naive HIV-Infected Patients | Clinical Infectious Diseases | 2006 | 98 |
| 29 | KMT2D mutations and TP53 disruptions are poor prognostic biomarkers in mantle cell lymphoma receiving high-dose therapy: a FIL study | Haematologica | 2020 | 96 |
| 30 | Lifestyle and Breast Cancer Recurrences: The DIANA-5 Trial | Tumori | 2012 | 88 |
| 31 | Low-dose oral imatinib in the treatment of systemic sclerosis interstitial lung disease unresponsive to cyclophosphamide: a phase II pilot study | Arthritis Research and Therapy | 2014 | 88 |
| 32 | Impact of COPD on Long-term Outcome After ST-Segment Elevation Myocardial Infarction Receiving Primary Percutaneous Coronary Intervention | Chest | 2013 | 86 |
| 33 | Usefulness and Safety of Transcatheter Ablation of Atrial Fibrillation in Patients With Hypertrophic Cardiomyopathy | American Journal of Cardiology | 2007 | 85 |
| 34 | Incidence and outcome of switching of oral platelet P2Y12 receptor inhibitors in patients with acute coronary syndromes undergoing percutaneous coronary intervention: the SCOPE registry | EuroIntervention | 2017 | 83 |
| 35 | A Third Locus Predisposing to Multiple Deletions of mtDNA in Autosomal Dominant Progressive External Ophthalmoplegia | American Journal of Human Genetics | 1999 | 82 |
| 36 | ROBUST: First report of phase III randomized study of lenalidomide/R‐CHOP (R2‐CHOP) vs placebo/R‐CHOP in previously untreated ABC‐type diffuse large B‐cell lymphoma | Hematological Oncology | 2019 | 82 |
| 37 | The Effect of On-line High-flux Hemofiltration Versus Low-flux Hemodialysis on Mortality in Chronic Kidney Failure: A Small Randomized Controlled Trial | American Journal of Kidney Diseases | 2008 | 79 |
| 38 | The genetic and clinical spectrum of a large cohort of patients with distal renal tubular acidosis | Kidney International | 2017 | 79 |
| 39 | Randomised controlled trial comparing single agent paclitaxel vs epidoxorubicin plus paclitaxel in patients with advanced ovarian cancer in early progression after platinum-based chemotherapy: an Italian Collaborative Study from the ‘Mario Negri’ Institute, Milan, G.O.N.O. (Gruppo Oncologico Nord Ovest) group and I.O.R. (Istituto Oncologico Romagnolo) group | British Journal of Cancer | 2004 | 77 |
| 40 | Metformin plus chemotherapy versus chemotherapy alone in the first-line treatment of HER2-negative metastatic breast cancer. The MYME randomized, phase 2 clinical trial | Breast Cancer Research and Treatment | 2019 | 77 |
| 41 | Fertility concerns, preservation strategies and quality of life in young women with breast cancer: Baseline results from an ongoing prospective cohort study in selected European Centers | Breast | 2019 | 76 |
| 42 | Electrocardiographic features of 431 consecutive, critically ill COVID-19 patients: an insight into the mechanisms of cardiac involvement | Europace | 2020 | 74 |
| 43 | Simplified Geriatric Assessment in Older Patients With Diffuse Large B-Cell Lymphoma: The Prospective Elderly Project of the Fondazione Italiana Linfomi | Journal of Clinical Oncology | 2021 | 74 |
| 44 | Managing chronic myeloid leukemia for treatment-free remission: a proposal from the GIMEMA CML WP | Blood Advances | 2019 | 66 |
| 45 | Dose-dense and high-dose chemotherapy plus rituximab with autologous stem cell transplantation for primary treatment of diffuse large B-cell lymphoma with a poor prognosis: a phase II multicenter study | Haematologica | 2009 | 65 |
| 46 | Metabolic heterogeneity on baseline 18FDG-PET/CT scan is a predictor of outcome in primary mediastinal B-cell lymphoma | Blood | 2018 | 63 |
| 47 | The Evolution of Adult-Onset Still Disease: An Observational and Comparative Study in a Cohort of 76 Italian Patients | Seminars in Arthritis and Rheumatism | 2011 | 62 |
| 48 | Two-Year Clinical Outcome With Drug-Eluting Stents Versus Bare-Metal Stents in a Real-World Registry of Unprotected Left Main Coronary Artery Stenosis from the Italian Society of Invasive Cardiology | American Journal of Cardiology | 2008 | 57 |
| 49 | Clinical impact of an inter-hospital transfer strategy in patients with ST-elevation myocardial infarction undergoing primary angioplasty: the Emilia-Romagna ST-segment elevation acute myocardial infarction network | European Heart Journal | 2008 | 56 |
| 50 | Efficacy and tolerability of bendamustine, bortezomib and dexamethasone in patients with relapsed-refractory multiple myeloma: a phase II study | Blood Cancer Journal | 2013 | 56 |
