| # | Title | Journal | Year | Citations |
|---|
| 1 | Presumed Asymptomatic Carrier Transmission of COVID-19 | JAMA - Journal of the American Medical Association | 2020 | 3,593 |
| 2 | Autophagy and autophagy-related proteins in cancer | Molecular Cancer | 2020 | 815 |
| 3 | The Applications of Radiomics in Precision Diagnosis and Treatment of Oncology: Opportunities and Challenges | Theranostics | 2019 | 554 |
| 4 | Sintilimab plus a bevacizumab biosimilar (IBI305) versus sorafenib in unresectable hepatocellular carcinoma (ORIENT-32): a randomised, open-label, phase 2–3 study | Lancet Oncology, The | 2021 | 459 |
| 5 | Dementia in China: epidemiology, clinical management, and research advances | Lancet Neurology, The | 2020 | 412 |
| 6 | The cost of Alzheimer's disease in China and re‐estimation of costs worldwide | Alzheimer's and Dementia | 2018 | 404 |
| 7 | Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies a susceptibility locus at PLCE1 | Nature Genetics | 2010 | 383 |
| 8 | Endovascular treatment versus standard medical treatment for vertebrobasilar artery occlusion (BEST): an open-label, randomised controlled trial | Lancet Neurology, The | 2020 | 383 |
| 9 | Prevalence of workplace violence against healthcare workers: a systematic review and meta-analysis | Occupational and Environmental Medicine | 2019 | 360 |
| 10 | Incidence and Etiology of Drug-Induced Liver Injury in Mainland China | Gastroenterology | 2019 | 346 |
| 11 | Impact of the COVID-19 Epidemic on Stroke Care and Potential Solutions | Stroke | 2020 | 259 |
| 12 | Double Kissing Crush Versus Provisional Stenting for Left Main Distal Bifurcation Lesions | Journal of the American College of Cardiology | 2017 | 256 |
| 13 | GUARDIN is a p53-responsive long non-coding RNA that is essential for genomic stability | Nature Cell Biology | 2018 | 239 |
| 14 | Discrepant gut microbiota markers for the classification of obesity-related metabolic abnormalities | Scientific Reports | 2019 | 235 |
| 15 | Expert Recommendations for Tracheal Intubation in Critically ill Patients with Noval Coronavirus Disease 2019 | Chinese Medical Sciences Journal | 2020 | 212 |
| 16 | Changes in colistin resistance and mcr-1 abundance in Escherichia coli of animal and human origins following the ban of colistin-positive additives in China: an epidemiological comparative study | Lancet Infectious Diseases, The | 2020 | 212 |
| 17 | CircACC1 Regulates Assembly and Activation of AMPK Complex under Metabolic Stress | Cell Metabolism | 2019 | 209 |
| 18 | Air-permeable, multifunctional, dual-energy-driven MXene-decorated polymeric textile-based wearable heaters with exceptional electrothermal and photothermal conversion performance | Journal of Materials Chemistry A | 2020 | 203 |
| 19 | Twice daily N-acetylcysteine 600 mg for exacerbations of chronic obstructive pulmonary disease (PANTHEON): a randomised, double-blind placebo-controlled trial | Lancet Respiratory Medicine,the | 2014 | 200 |
| 20 | Aging and age‐related diseases: from mechanisms to therapeutic strategies | Biogerontology | 2021 | 200 |
| 21 | Clinical application of massively parallel sequencing‐based prenatal noninvasive fetal trisomy test for trisomies 21 and 18 in 11 105 pregnancies with mixed risk factors | Prenatal Diagnosis | 2012 | 197 |
| 22 | Upregulated lncRNA SNHG1 contributes to progression of non-small cell lung cancer through inhibition of miR-101-3p and activation of Wnt/β-catenin signaling pathway | Oncotarget | 2017 | 193 |
| 23 | Robust breast cancer detection in mammography and digital breast tomosynthesis using an annotation-efficient deep learning approach | Nature Medicine | 2021 | 187 |
| 24 | Grading of Gliomas by Using Monoexponential, Biexponential, and Stretched Exponential Diffusion-weighted MR Imaging and Diffusion Kurtosis MR Imaging | Radiology | 2016 | 184 |
| 25 | Toripalimab plus chemotherapy in treatment-naïve, advanced esophageal squamous cell carcinoma (JUPITER-06): A multi-center phase 3 trial | Cancer Cell | 2022 | 177 |
| 26 | Prevalence and factors for anxiety during the coronavirus disease 2019 (COVID-19) epidemic among the teachers in China | Journal of Affective Disorders | 2020 | 172 |
| 27 | Multifunctional phototheranostic nanomedicine for cancer imaging and treatment | Materials Today Bio | 2020 | 167 |
| 28 | Effect of Ticagrelor Plus Aspirin, Ticagrelor Alone, or Aspirin Alone on Saphenous Vein Graft Patency 1 Year After Coronary Artery Bypass Grafting | JAMA - Journal of the American Medical Association | 2018 | 163 |
| 29 | Impaired meningeal lymphatic drainage in patients with idiopathic Parkinson’s disease | Nature Medicine | 2021 | 160 |
| 30 | Impact of the Complexity of Bifurcation Lesions Treated With Drug-Eluting Stents | JACC: Cardiovascular Interventions | 2014 | 153 |
| 31 | Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations | Nature Genetics | 2014 | 148 |
| 32 | Predominant gut Lactobacillus murinus strain mediates anti-inflammaging effects in calorie-restricted mice | Microbiome | 2018 | 141 |
| 33 | Ti3C2Tx MXene-Decorated Nanoporous Polyethylene Textile for Passive and Active Personal Precision Heating | ACS Nano | 2021 | 141 |
| 34 | Hydrogen sulfide promotes autophagy of hepatocellular carcinoma cells through the PI3K/Akt/mTOR signaling pathway | Cell Death and Disease | 2017 | 140 |
| 35 | Long noncoding RNA LINC00662 promotes M2 macrophage polarization and hepatocellular carcinoma progression via activating Wnt/β‐catenin signaling | Molecular Oncology | 2020 | 139 |
| 36 | 2020 Chinese guidelines for ultrasound malignancy risk stratification of thyroid nodules: the C-TIRADS | Endocrine | 2020 | 139 |
| 37 | METTL14 aggravates endothelial inflammation and atherosclerosis by increasing FOXO1 N6-methyladeosine modifications | Theranostics | 2020 | 136 |
| 38 | 2D and 3D CT Radiomics Features Prognostic Performance Comparison in Non-Small Cell Lung Cancer | Translational Oncology | 2017 | 130 |
| 39 | Stroke prevention and control system in China: CSPPC-Stroke Program | International Journal of Stroke | 2021 | 125 |
| 40 | Exosomal miR-4443 promotes cisplatin resistance in non-small cell lung carcinoma by regulating FSP1 m6A modification-mediated ferroptosis | Life Sciences | 2021 | 123 |
| 41 | Susceptibility‐weighted imaging: current status and future directions | NMR in Biomedicine | 2017 | 121 |
| 42 | Biocompatible conductive hydrogels based on dextran and aniline trimer as electro-responsive drug delivery system for localized drug release | International Journal of Biological Macromolecules | 2019 | 121 |
| 43 | Laparoscopic versus open pancreatoduodenectomy for pancreatic or periampullary tumours: a multicentre, open-label, randomised controlled trial | The Lancet Gastroenterology and Hepatology | 2021 | 120 |
| 44 | Mitochondrial fission-induced mtDNA stress promotes tumor-associated macrophage infiltration and HCC progression | Oncogene | 2019 | 119 |
| 45 | Ultrathin Titanium Carbide (MXene) Films for High‐Temperature Thermal Camouflage | Advanced Functional Materials | 2021 | 118 |
| 46 | Alveolar type 2 progenitor cells for lung injury repair | Cell Death Discovery | 2019 | 117 |
| 47 | Development and validation of a prediction rule for estimating gastric cancer risk in the Chinese high-risk population: a nationwide multicentre study | Gut | 2019 | 116 |
| 48 | COVID-19 Disease With Positive Fecal and Negative Pharyngeal and Sputum Viral Tests | American Journal of Gastroenterology | 2020 | 115 |
| 49 | Microvesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Facilitate Tubular Epithelial Cell Dedifferentiation and Growth via Hepatocyte Growth Factor Induction | PLoS ONE | 2015 | 114 |
| 50 | Camrelizumab Plus Carboplatin and Paclitaxel as First-Line Treatment for Advanced Squamous NSCLC (CameL-Sq): A Phase 3 Trial | Journal of Thoracic Oncology | 2022 | 114 |
