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Top Articles

#TitleJournalYearCitations
1Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALSNature Neuroscience2015528
2Neuronal medium that supports basic synaptic functions and activity of human neurons in vitroProceedings of the National Academy of Sciences of the United States of America2015317
3Enzyme‐Responsive Nanoparticles for Targeted Accumulation and Prolonged Retention in Heart Tissue after Myocardial InfarctionAdvanced Materials2015229
4Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cellsProceedings of the National Academy of Sciences of the United States of America2014225
5The Ro60 autoantigen binds endogenous retroelements and regulates inflammatory gene expressionScience2015225
6Connections between TET proteins and aberrant DNA modification in cancerTrends in Genetics2014221
7Differential L1 regulation in pluripotent stem cells of humans and apesNature2013220
8Stimulation of adipogenesis of adult adipose-derived stem cells using substrates that mimic the stiffness of adipose tissueBiomaterials2013197
9First-in-Man Study of a Cardiac Extracellular Matrix Hydrogel in Early and Late Myocardial Infarction PatientsJACC Basic To Translational Science2019183
10TET proteins and 5‐methylcytosine oxidation in hematological cancersImmunological Reviews2015158
11Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactionsCell Research2020149
12ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemiaProceedings of the National Academy of Sciences of the United States of America2013148
13The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosineNature Cell Biology2015137
14Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesisProceedings of the National Academy of Sciences of the United States of America2017129
15A panel of induced pluripotent stem cells from chimpanzees: a resource for comparative functional genomicsELife2015114
16Image-based detection and targeting of therapy resistance in pancreatic adenocarcinomaNature2016114
17Deletion of cavin genes reveals tissue-specific mechanisms for morphogenesis of endothelial caveolaeNature Communications2013113
18Ubiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascadeProceedings of the National Academy of Sciences of the United States of America201499
19Quantification of decellularized human myocardial matrix: A comparison of six patientsProteomics - Clinical Applications201697
20AMPD2 Regulates GTP Synthesis and Is Mutated in a Potentially Treatable Neurodegenerative Brainstem DisorderCell201394
21Musashi Signaling in Stem Cells and CancerAnnual Review of Cell and Developmental Biology201592
22TCR signal strength controls thymic differentiation of iNKT cell subsetsNature Communications201879
23Cell Instructive Microporous Scaffolds through Interface EngineeringJournal of the American Chemical Society201266
24β-Arrestin2 mediates the initiation and progression of myeloid leukemiaProceedings of the National Academy of Sciences of the United States of America201253
25Neuron-Targeted Caveolin-1 Improves Molecular Signaling, Plasticity, and Behavior Dependent on the Hippocampus in Adult and Aged MiceBiological Psychiatry201751
26RNA-binding protein hnRNPLL regulates mRNA splicing and stability during B-cell to plasma-cell differentiationProceedings of the National Academy of Sciences of the United States of America201549
27Generation of Complete Multi−Cell Type Lung Organoids From Human Embryonic and Patient‐Specific Induced Pluripotent Stem Cells for Infectious Disease Modeling and Therapeutics ValidationCurrent Protocols in Stem Cell Biology202043
28Rethinking Remdesivir: Synthesis, Antiviral Activity, and Pharmacokinetics of Oral Lipid ProdrugsAntimicrobial Agents and Chemotherapy202143
29Patch-Seq Protocol to Analyze the Electrophysiology, Morphology and Transcriptome of Whole Single Neurons Derived From Human Pluripotent Stem CellsFrontiers in Molecular Neuroscience201837
30An in vivo genome-wide CRISPR screen identifies the RNA-binding protein Staufen2 as a key regulator of myeloid leukemiaNature Cancer202037
31Hypoxia and Trophoblast Differentiation: A Key Role for PPARγStem Cells and Development201334
32Injectable ECM Scaffolds for Cardiac RepairMethods in Molecular Biology201432
33Mechanism of Action of Methotrexate Against Zika VirusViruses201931
34Decidual Regulatory T Cells in Placental Pathology and Pregnancy ComplicationsAmerican Journal of Reproductive Immunology201330
35A Rare Human Syndrome Provides Genetic Evidence that WNT Signaling Is Required for Reprogramming of Fibroblasts to Induced Pluripotent Stem CellsCell Reports201429
36Isoflurane Reversibly Destabilizes Hippocampal Dendritic Spines by an Actin-Dependent MechanismPLoS ONE201428
37TET proteins in natural and induced differentiationCurrent Opinion in Genetics and Development201727
38Decellularized Extracellular Matrix Hydrogels as a Delivery Platform for MicroRNA and Extracellular Vesicle TherapeuticsAdvanced Therapeutics201826
39AMPD1: a novel therapeutic target for reversing insulin resistanceBMC Endocrine Disorders201424
40The Period protein homolog LIN-42 negatively regulates microRNA biogenesis in C. elegansDevelopmental Biology201424
41Development and Validation of a Phenotypic High-Content Imaging Assay for Assessing the Antiviral Activity of Small-Molecule Inhibitors Targeting Zika VirusAntimicrobial Agents and Chemotherapy201822
425-Hydroxymethylcytosine-mediated active demethylation is required for mammalian neuronal differentiation and functionELife202121
43Mechanical Principles Governing the Shapes of Dendritic SpinesFrontiers in Physiology202119
44Glial cells maintain synapses by inhibiting an activity-dependent retrograde protease signalPLoS Genetics201917
45Post-degradation forces kick inNature Materials201316
46Caveolin-1 Phosphorylation Is Essential for Axonal Growth of Human Neurons Derived From iPSCsFrontiers in Cellular Neuroscience201916
47Amyloidogenic Processing of Amyloid Precursor Protein Drives Stretch-Induced Disruption of Axonal Transport in hiPSC-Derived NeuronsJournal of Neuroscience202114
48Effect of isolated AMP deaminase deficiency on skeletal muscle functionMolecular Genetics and Metabolism Reports201411
49Parkinson’s disease patient-specific neuronal networks carrying the LRRK2 G2019S mutation unveil early functional alterations that predate neurodegenerationNpj Parkinson's Disease202111
50Pancreas Development Ex Vivo: Culturing Embryonic Pancreas Explants on Permeable Culture Inserts, with Fibronectin-Coated Glass Microwells, or Embedded in Three-Dimensional Matrigel™Methods in Molecular Biology201411