| # | Title | Journal | Year | Citations |
|---|
| 1 | 2019 update of the EULAR recommendations for the management of systemic lupus erythematosus | Annals of the Rheumatic Diseases | 2019 | 1,265 |
| 2 | An international association between Helicobacter pylori infection and gastric cancer | Lancet, The | 1993 | 1,134 |
| 3 | Association analysis identifies 65 new breast cancer risk loci | Nature | 2017 | 1,099 |
| 4 | Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes | American Journal of Human Genetics | 2019 | 711 |
| 5 | Clinical validity of circulating tumour cells in patients with metastatic breast cancer: a pooled analysis of individual patient data | Lancet Oncology, The | 2014 | 703 |
| 6 | Real-time ultrasound-guided catheterisation of the internal jugular vein: a prospective comparison with the landmark technique in critical care patients | Critical Care | 2006 | 542 |
| 7 | Prognostic Value of Fractional Flow Reserve | Journal of the American College of Cardiology | 2014 | 513 |
| 8 | 2019 Update of the Joint European League Against Rheumatism and European Renal Association–European Dialysis and Transplant Association (EULAR/ERA–EDTA) recommendations for the management of lupus nephritis | Annals of the Rheumatic Diseases | 2020 | 463 |
| 9 | The Application of Esophageal Pressure Measurement in Patients with Respiratory Failure | American Journal of Respiratory and Critical Care Medicine | 2014 | 443 |
| 10 | Prognostic Value of Mature MicroRNA-21 and MicroRNA-205 Overexpression in Non–Small Cell Lung Cancer by Quantitative Real-Time RT-PCR | Clinical Chemistry | 2008 | 415 |
| 11 | Afatinib versus erlotinib as second-line treatment of patients with advanced squamous cell carcinoma of the lung (LUX-Lung 8): an open-label randomised controlled phase 3 trial | Lancet Oncology, The | 2015 | 389 |
| 12 | Germline and somatic SMARCA4 mutations characterize small cell carcinoma of the ovary, hypercalcemic type | Nature Genetics | 2014 | 383 |
| 13 | Gender-Related Differences in Presentation, Treatment, and Outcome of Patients With Atrial Fibrillation in Europe | Journal of the American College of Cardiology | 2007 | 370 |
| 14 | Lung ultrasound in critically ill patients: comparison with bedside chest radiography | Intensive Care Medicine | 2011 | 361 |
| 15 | International Nosocomial Infection Control Consortium (INICC) report, data summary of 36 countries, for 2004-2009 | American Journal of Infection Control | 2012 | 356 |
| 16 | International Nosocomial Infection Control Consortium (INICC) report, data summary for 2003-2008, issued June 2009 | American Journal of Infection Control | 2010 | 355 |
| 17 | Antithrombotic treatment in real-life atrial fibrillation patients: a report from the Euro Heart Survey on Atrial Fibrillation | European Heart Journal | 2006 | 353 |
| 18 | Mutations in proto-oncogene GFI1 cause human neutropenia and target ELA2 | Nature Genetics | 2003 | 350 |
| 19 | A global assessment of phthalates burden and related links to health effects | Environment International | 2016 | 332 |
| 20 | Ultrasound elastography for musculoskeletal applications | British Journal of Radiology | 2012 | 298 |
| 21 | Safety of pleurodesis with talc poudrage in malignant pleural effusion: a prospective cohort study | Lancet, The | 2007 | 291 |
| 22 | Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer | Nature Genetics | 2017 | 289 |
| 23 | Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer | British Journal of Cancer | 2009 | 283 |
| 24 | A prospective survey in European Society of Cardiology member countries of atrial fibrillation management: baseline results of EURObservational Research Programme Atrial Fibrillation (EORP-AF) Pilot General Registry | Europace | 2014 | 280 |
| 25 | CT Evaluation of Mesenteric Panniculitis | American Journal of Roentgenology | 2000 | 264 |
| 26 | Prognosis, disease progression, and treatment of atrial fibrillation patients during 1 year: follow-up of the Euro Heart Survey on Atrial Fibrillation | European Heart Journal | 2008 | 247 |
| 27 | Consensus statement on abusive head trauma in infants and young children | Pediatric Radiology | 2018 | 235 |
| 28 | Magnetic resonance imaging for the clinical management of rectal cancer patients: recommendations from the 2012 European Society of Gastrointestinal and Abdominal Radiology (ESGAR) consensus meeting | European Radiology | 2013 | 222 |
| 29 | Respiratory gated diffusion-weighted imaging of the liver: value of apparent diffusion coefficient measurements in the differentiation between most commonly encountered benign and malignant focal liver lesions | European Radiology | 2008 | 220 |
| 30 | Risk factors of carbapenem-resistant Klebsiella pneumoniae infections: a matched case control study | Journal of Antimicrobial Chemotherapy | 2007 | 209 |
| 31 | CCR9–Positive lymphocytes and thymus-expressed chemokine distinguish small bowel from colonic Crohn's disease | Gastroenterology | 2001 | 194 |
| 32 | Pleural Effusions in Hematologic Malignancies | Chest | 2004 | 194 |
| 33 | Bedside waveforms interpretation as a tool to identify patient-ventilator asynchronies | Intensive Care Medicine | 2006 | 193 |
| 34 | Diagnostic precision of carcinoembryonic antigen in the detection of recurrence of colorectal cancer | Surgical Oncology | 2009 | 190 |
| 35 | Myeloid-derived suppressor cell measurements in fresh and cryopreserved blood samples | Journal of Immunological Methods | 2012 | 185 |
| 36 | A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer | Nature Genetics | 2018 | 184 |
| 37 | Anemia in Pregnancy | Annals of the New York Academy of Sciences | 2000 | 183 |
| 38 | Aerosolized plus Intravenous Colistin versus Intravenous Colistin Alone for the Treatment of Ventilator‐Associated Pneumonia: A Matched Case‐Control Study | Clinical Infectious Diseases | 2010 | 181 |
| 39 | Importance of Leadership Style towards Quality of Care Measures in Healthcare Settings: A Systematic Review | Healthcare (Switzerland) | 2017 | 177 |
| 40 | Assessment of Crohn?s disease activity in the small bowel with MR and conventional enteroclysis: preliminary results | European Radiology | 2004 | 172 |
| 41 | Lung- and Diaphragm-Protective Ventilation | American Journal of Respiratory and Critical Care Medicine | 2020 | 166 |
| 42 | Dietary Guidance From the International Organization for the Study of Inflammatory Bowel Diseases | Clinical Gastroenterology and Hepatology | 2020 | 161 |
| 43 | Acute cholecystitis in high-risk patients: percutaneous cholecystostomy vs conservative treatment | European Radiology | 2002 | 159 |
| 44 | Clinical significance of the pharmacokinetic and pharmacodynamic characteristics of fosfomycin for the treatment of patients with systemic infections | International Journal of Antimicrobial Agents | 2009 | 159 |
| 45 | MR enteroclysis: technical considerations and clinical applications | European Radiology | 2002 | 156 |
| 46 | Integrated care pathways for airway diseases (AIRWAYS-ICPs) | European Respiratory Journal | 2014 | 154 |
| 47 | Effect of duration of adjuvant chemotherapy for patients with stage III colon cancer (IDEA collaboration): final results from a prospective, pooled analysis of six randomised, phase 3 trials | Lancet Oncology, The | 2020 | 152 |
| 48 | Respiratory Drive in Critically Ill Patients. Pathophysiology and Clinical Implications | American Journal of Respiratory and Critical Care Medicine | 2020 | 151 |
| 49 | Imaging of small intestinal Crohn’s disease: comparison between MR enteroclysis and conventional enteroclysis | European Radiology | 2006 | 150 |
| 50 | Classification of small bowel Crohn's subtypes based on multimodality imaging | Radiologic Clinics of North America | 2003 | 149 |
