| # | Title | Journal | Year | Citations |
|---|
| 1 | The 2015 World Health Organization Classification of Lung Tumors | Journal of Thoracic Oncology | 2015 | 3,313 |
| 2 | Comprehensive genomic profiles of small cell lung cancer | Nature | 2015 | 1,634 |
| 3 | Revisions of international consensus Fukuoka guidelines for the management of IPMN of the pancreas | Pancreatology | 2017 | 1,208 |
| 4 | Mutations of the Epidermal Growth Factor Receptor Gene Predict Prolonged Survival After Gefitinib Treatment in Patients With Non–Small-Cell Lung Cancer With Postoperative Recurrence | Journal of Clinical Oncology | 2005 | 922 |
| 5 | Alectinib versus crizotinib in patients with ALK -positive non-small-cell lung cancer (J-ALEX): an open-label, randomised phase 3 trial | Lancet, The | 2017 | 753 |
| 6 | Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2010 for the treatment of colorectal cancer | International Journal of Clinical Oncology | 2012 | 658 |
| 7 | PD-L1 Immunohistochemistry Comparability Study in Real-Life Clinical Samples: Results of Blueprint Phase 2 Project | Journal of Thoracic Oncology | 2018 | 589 |
| 8 | A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer | Nature Medicine | 2012 | 510 |
| 9 | Quantitative Analysis of Epstein-Barr Virus Load by Using a Real-Time PCR Assay | Journal of Clinical Microbiology | 1999 | 499 |
| 10 | Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 496 |
| 11 | Contribution of carbohydrate antigens sialyl Lewis A and sialyl Lewis X to adhesion of human cancer cells to vascular endothelium | Cancer Research | 1993 | 439 |
| 12 | Updated Molecular Testing Guideline for the Selection of Lung Cancer Patients for Treatment With Targeted Tyrosine Kinase Inhibitors | Journal of Thoracic Oncology | 2018 | 408 |
| 13 | The clinical significance of human leukocyte antigen (HLA) allele compatibility in patients receiving a marrow transplant from serologically HLA-A, HLA-B, and HLA-DR matched unrelated donors | Blood | 2002 | 396 |
| 14 | Senile EBV+ B-Cell Lymphoproliferative Disorders | American Journal of Surgical Pathology | 2003 | 364 |
| 15 | Phase I Study of KW-0761, a Defucosylated Humanized Anti-CCR4 Antibody, in Relapsed Patients With Adult T-Cell Leukemia-Lymphoma and Peripheral T-Cell Lymphoma | Journal of Clinical Oncology | 2010 | 351 |
| 16 | Genome-Wide Profiling of DNA Methylation Reveals a Class of Normally Methylated CpG Island Promoters | PLoS Genetics | 2007 | 319 |
| 17 | Depth of invasion as a predictive factor for cervical lymph node metastasis in tongue carcinoma | Head and Neck | 1997 | 286 |
| 18 | Characterization of Small Solid Tumors in the Pancreas: The Value of Contrast-Enhanced Harmonic Endoscopic Ultrasonography | American Journal of Gastroenterology | 2012 | 282 |
| 19 | Carbohydrate-mediated cell adhesion involved in hematogenous metastasis of cancer | Glycoconjugate Journal | 1997 | 281 |
| 20 | Hepatitis B and C Virus Infection and Hepatocellular Carcinoma in China: A Review of Epidemiology and Control Measures | Journal of Epidemiology | 2011 | 267 |
| 21 | Targeting HER2 aberrations as actionable drivers in lung cancers: phase II trial of the pan-HER tyrosine kinase inhibitor dacomitinib in patients with HER2-mutant or amplified tumors | Annals of Oncology | 2015 | 254 |
| 22 | New staging system and a registry for perihilar cholangiocarcinoma | Hepatology | 2011 | 252 |
| 23 | A Novel Mechanism for the Inhibition of Hyaluronan Biosynthesis by 4-Methylumbelliferone | Journal of Biological Chemistry | 2004 | 248 |
| 24 | High-risk HLA allele mismatch combinations responsible for severe acute graft-versus-host disease and implication for its molecular mechanism | Blood | 2007 | 246 |
| 25 | Updated Molecular Testing Guideline for the Selection of Lung Cancer Patients for Treatment With Targeted Tyrosine Kinase Inhibitors | Journal of Molecular Diagnostics | 2018 | 241 |
| 26 | Clonal heterogeneity in differentiation potential of immortalized human mesenchymal stem cells | Biochemical and Biophysical Research Communications | 2002 | 233 |
| 27 | Prognostic factors for mature natural killer (NK) cell neoplasms: aggressive NK cell leukemia and extranodal NK cell lymphoma, nasal type | Annals of Oncology | 2010 | 228 |
| 28 | Genetic Polymorphisms of the Human PNPLA3 Gene Are Strongly Associated with Severity of Non-Alcoholic Fatty Liver Disease in Japanese | PLoS ONE | 2012 | 228 |
| 29 | Predictors of Survival in Patients With Bone Metastasis of Lung Cancer | Clinical Orthopaedics and Related Research | 2008 | 227 |
| 30 | Conservative therapy for adenocarcinoma and atypical endometrial hyperplasia of the endometrium in young women: central pathologic review and treatment outcome | Cancer Letters | 2001 | 226 |
| 31 | Aggressive natural killer-cell leukemia revisited: large granular lymphocyte leukemia of cytotoxic NK cells | Leukemia | 2004 | 224 |
| 32 | Improved outcome of adult T cell leukemia/lymphoma with allogeneic hematopoietic stem cell transplantation | Bone Marrow Transplantation | 2001 | 222 |
| 33 | Heterogeneous Distribution of EGFR Mutations Is Extremely Rare in Lung Adenocarcinoma | Journal of Clinical Oncology | 2011 | 218 |
| 34 | Best Practices Recommendations for Diagnostic Immunohistochemistry in Lung Cancer | Journal of Thoracic Oncology | 2019 | 212 |
| 35 | Effect of hepatitis C virus infection on the risk of non-Hodgkin's lymphoma: A meta-analysis of epidemiological studies | Cancer Science | 2004 | 208 |
| 36 | 6-Sulfo LacNAc, a Novel Carbohydrate Modification of PSGL-1, Defines an Inflammatory Type of Human Dendritic Cells | Immunity | 2002 | 206 |
| 37 | Reproducibility of histopathological subtypes and invasion in pulmonary adenocarcinoma. An international interobserver study | Modern Pathology | 2012 | 206 |
| 38 | KIR Ligands and Prediction of Relapse after Unrelated Donor Hematopoietic Cell Transplantation for Hematologic Malignancy | Biology of Blood and Marrow Transplantation | 2006 | 201 |
| 39 | Lineage-Specific Dependency of Lung Adenocarcinomas on the Lung Development Regulator TTF-1 | Cancer Research | 2007 | 200 |
| 40 | Multi-step Carcinogenesis Model for Adult T-cell Leukemia | Japanese Journal of Cancer Research | 1989 | 198 |
| 41 | TGF-β synergizes with defects in the Hippo pathway to stimulate human malignant mesothelioma growth | Journal of Experimental Medicine | 2012 | 197 |
| 42 | Biological and clinical implications of EGFR mutations in lung cancer | International Journal of Clinical Oncology | 2006 | 194 |
| 43 | The prognostic significance of number of positive nodes in cervical carcinoma stages IB, IIA, and IIB | Cancer | 1990 | 187 |
| 44 | Association between polymorphisms of folate- and methionine-metabolizing enzymes and susceptibility to malignant lymphoma | Blood | 2001 | 185 |
| 45 | Multi-institutional studies on hyperthermia using an 8-MHz radiofrequency capacitive heating device (thermotron RF-8) in combination with radiation for cancer therapy | Cancer | 1986 | 177 |
| 46 | Expression of Lewisa, Lewisb, Lewisx, Lewisy, siayl-Lewisa, and sialyl-Lewisx blood group antigens in human gastric carcinoma and in normal gastric tissue | Cancer Research | 1989 | 177 |
| 47 | Gene-environment interaction between an aldehyde dehydrogenase-2 (ALDH2) polymorphism and alcohol consumption for the risk of esophageal cancer | Carcinogenesis | 2001 | 176 |
| 48 | Studies on a New Human Cell Line (SiHa) Derived from Carcinoma of Uterus. I. Its Establishment and Morphology | Experimental Biology and Medicine | 1970 | 175 |
| 49 | The International Association for the Study of Lung Cancer Consensus Statement on Optimizing Management of EGFR Mutation–Positive Non–Small Cell Lung Cancer: Status in 2016 | Journal of Thoracic Oncology | 2016 | 173 |
| 50 | Biological activities and mechanisms of action of PGJ2 and related compounds: an update | Prostaglandins Leukotrienes and Essential Fatty Acids | 1992 | 172 |
