| # | Title | Journal | Year | Citations |
|---|
| 1 | Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines | Journal of Extracellular Vesicles | 2018 | 6,961 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 3 | Antitumour actions of interferons: implications for cancer therapy | Nature Reviews Cancer | 2016 | 688 |
| 4 | Immune modulation by bacterial outer membrane vesicles | Nature Reviews Immunology | 2015 | 672 |
| 5 | Recent insights into targeting the IL-6 cytokine family in inflammatory diseases and cancer | Nature Reviews Immunology | 2018 | 662 |
| 6 | Circulating levels of IGF-1 directly regulate bone growth and density | Journal of Clinical Investigation | 2002 | 469 |
| 7 | The consequences of fetal growth restriction on brain structure and neurodevelopmental outcome | Journal of Physiology | 2016 | 384 |
| 8 | Endometrial stem/progenitor cells: the first 10 years | Human Reproduction Update | 2016 | 364 |
| 9 | Therapeutically exploiting STAT3 activity in cancer — using tissue repair as a road map | Nature Reviews Cancer | 2019 | 354 |
| 10 | IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction | Nature Immunology | 2015 | 352 |
| 11 | International Union of Pharmacology. LXV. The Pharmacology and Classification of the Nuclear Receptor Superfamily: Glucocorticoid, Mineralocorticoid, Progesterone, and Androgen Receptors | Pharmacological Reviews | 2006 | 350 |
| 12 | The diagnosis of male infertility: an analysis of the evidence to support the development of global WHO guidance—challenges and future research opportunities | Human Reproduction Update | 2017 | 320 |
| 13 | Tumor-Specific CD4+ T Cells Have a Major “Post-Licensing” Role in CTL Mediated Anti-Tumor Immunity | Journal of Immunology | 2000 | 306 |
| 14 | Bacterial membrane vesicles transport their DNA cargo into host cells | Scientific Reports | 2017 | 267 |
| 15 | Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond | PLoS Pathogens | 2016 | 244 |
| 16 | Disorders of sex development: insights from targeted gene sequencing of a large international patient cohort | Genome Biology | 2016 | 241 |
| 17 | Neonatal Morbidities of Fetal Growth Restriction: Pathophysiology and Impact | Frontiers in Endocrinology | 2019 | 237 |
| 18 | Identification of SOX3 as an XX male sex reversal gene in mice and humans | Journal of Clinical Investigation | 2011 | 234 |
| 19 | Targeted drug delivery using genetically engineered diatom biosilica | Nature Communications | 2015 | 226 |
| 20 | Mitochondrial dysfunction in oocytes of obese mothers: transmission to offspring and reversal by pharmacological endoplasmic reticulum stress inhibitors | Development (Cambridge) | 2015 | 223 |
| 21 | TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells | Cell Reports | 2020 | 223 |
| 22 | Fertile ground: human endometrial programming and lessons in health and disease | Nature Reviews Endocrinology | 2016 | 216 |
| 23 | TLR7 gain-of-function genetic variation causes human lupus | Nature | 2022 | 208 |
| 24 | Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease | Nature | 2020 | 198 |
| 25 | Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition) | European Journal of Immunology | 2021 | 198 |
| 26 | Hedgehog Signaling in the Maintenance of Cancer Stem Cells | Cancers | 2015 | 190 |
| 27 | Infectious, inflammatory and ‘autoimmune’ male factor infertility: how do rodent models inform clinical practice? | Human Reproduction Update | 2018 | 188 |
| 28 | A Review of Animal Models of Intervertebral Disc Degeneration: Pathophysiology, Regeneration, and Translation to the Clinic | BioMed Research International | 2016 | 184 |
| 29 | The JAK/STAT pathway in obesity and diabetes | FEBS Journal | 2016 | 184 |
| 30 | Diabetes-induced hyperglycemia impairs male reproductive function: a systematic review | Human Reproduction Update | 2018 | 181 |
| 31 | Cardiovascular transition at birth: a physiological sequence | Pediatric Research | 2015 | 170 |
| 32 | IL‐1β and IL‐18: inflammatory markers or mediators of hypertension? | British Journal of Pharmacology | 2014 | 168 |
| 33 | Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage, and dysfunction in salt-sensitive hypertension | Cardiovascular Research | 2019 | 165 |
| 34 | More than 18,000 effectors in the Legionella genus genome provide multiple, independent combinations for replication in human cells | Proceedings of the National Academy of Sciences of the United States of America | 2019 | 164 |
| 35 | The microgenderome revealed: sex differences in bidirectional interactions between the microbiota, hormones, immunity and disease susceptibility | Seminars in Immunopathology | 2019 | 160 |
| 36 | Animal and translational models of SARS-CoV-2 infection and COVID-19 | Mucosal Immunology | 2020 | 155 |
| 37 | Respiratory transition in the newborn: a three-phase process | Archives of Disease in Childhood: Fetal and Neonatal Edition | 2016 | 153 |
| 38 | Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition | Scientific Reports | 2016 | 150 |
| 39 | Amnion Epithelial Cell-Derived Exosomes Restrict Lung Injury and Enhance Endogenous Lung Repair | Stem Cells Translational Medicine | 2018 | 150 |
| 40 | Cytokines in Male Fertility and Reproductive Pathologies: Immunoregulation and Beyond | Frontiers in Endocrinology | 2017 | 146 |
| 41 | Extracellular Vesicles in Human Reproduction in Health and Disease | Endocrine Reviews | 2018 | 146 |
| 42 | Inflammasome activity is essential for one kidney/deoxycorticosterone acetate/salt‐induced hypertension in mice | British Journal of Pharmacology | 2016 | 143 |
| 43 | Molecular profiling of low grade serous ovarian tumours identifies novel candidate driver genes | Oncotarget | 2015 | 142 |
| 44 | A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands | Science Immunology | 2018 | 142 |
| 45 | Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation | Nature Communications | 2018 | 142 |
| 46 | How Is the Number of Primordial Follicles in the Ovarian Reserve Established?1 | Biology of Reproduction | 2015 | 141 |
| 47 | A guide to miRNAs in inflammation and innate immune responses | FEBS Journal | 2018 | 141 |
| 48 | Structural basis of TIR-domain-assembly formation in MAL- and MyD88-dependent TLR4 signaling | Nature Structural and Molecular Biology | 2017 | 140 |
| 49 | Establishing normal values for pediatric nighttime sleep measured by actigraphy: a systematic review and meta-analysis | Sleep | 2018 | 139 |
| 50 | Helicobacter pylori Outer Membrane Vesicle Size Determines Their Mechanisms of Host Cell Entry and Protein Content | Frontiers in Immunology | 2018 | 139 |
