| # | Title | Journal | Year | Citations |
|---|
| 1 | limma powers differential expression analyses for RNA-sequencing and microarray studies | Nucleic Acids Research | 2015 | 26,032 |
| 2 | A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 | Lancet, The | 2012 | 9,397 |
| 3 | Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 | Lancet, The | 2012 | 6,376 |
| 4 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 5 | The global burden of group A streptococcal diseases | Lancet Infectious Diseases, The | 2005 | 2,384 |
| 6 | Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics | PLoS Genetics | 2014 | 2,012 |
| 7 | A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology | Cell | 2008 | 1,766 |
| 8 | Statistical tests, P values, confidence intervals, and power: a guide to misinterpretations | European Journal of Epidemiology | 2016 | 1,761 |
| 9 | Assessment and Development of Executive Function (EF) During Childhood | Child Neuropsychology | 2002 | 1,566 |
| 10 | Opportunities and challenges in long-read sequencing data analysis | Genome Biology | 2020 | 1,536 |
| 11 | Antithrombotic Therapy in Neonates and Children | Chest | 2012 | 1,229 |
| 12 | Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis | Nature | 2015 | 1,210 |
| 13 | Guidelines and definitions for research on epithelial–mesenchymal transition | Nature Reviews Molecular Cell Biology | 2020 | 1,195 |
| 14 | Cooling for newborns with hypoxic ischaemic encephalopathy | The Cochrane Library | 2013 | 1,088 |
| 15 | The State of US Health, 1990-2016 | JAMA - Journal of the American Medical Association | 2018 | 1,042 |
| 16 | Mitochondrial diseases | Nature Reviews Disease Primers | 2016 | 1,001 |
| 17 | Epithelial—mesenchymal and mesenchymal—epithelial transitions in carcinoma progression | Journal of Cellular Physiology | 2007 | 957 |
| 18 | Early, Accurate Diagnosis and Early Intervention in Cerebral Palsy | JAMA Pediatrics | 2017 | 898 |
| 19 | Neurodevelopmental outcome at 2 years of age after general anaesthesia and awake-regional anaesthesia in infancy (GAS): an international multicentre, randomised controlled trial | Lancet, The | 2016 | 865 |
| 20 | Prevalence of challenge-proven IgE-mediated food allergy using population-based sampling and predetermined challenge criteria in infants | Journal of Allergy and Clinical Immunology | 2011 | 851 |
| 21 | Uniformity of rotavirus strain nomenclature proposed by the Rotavirus Classification Working Group (RCWG) | Archives of Virology | 2011 | 827 |
| 22 | ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro | Nature | 2005 | 826 |
| 23 | Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): long-term results from a prospective, multicentre trial | Lancet Oncology, The | 2006 | 811 |
| 24 | Cannabis use and mental health in young people: cohort study | BMJ: British Medical Journal | 2002 | 809 |
| 25 | The reliability of three-dimensional kinematic gait measurements: A systematic review | Gait and Posture | 2009 | 808 |
| 26 | Abnormal Cerebral Structure Is Present at Term in Premature Infants | Pediatrics | 2005 | 775 |
| 27 | Neurobehavioral Outcomes of School-age Children Born Extremely Low Birth Weight or Very Preterm in the 1990s | JAMA - Journal of the American Medical Association | 2003 | 773 |
| 28 | Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) | European Journal of Immunology | 2019 | 766 |
| 29 | Robust hyperparameter estimation protects against hypervariable genes and improves power to detect differential expression | Annals of Applied Statistics | 2016 | 764 |
| 30 | International Union of Immunological Societies: 2017 Primary Immunodeficiency Diseases Committee Report on Inborn Errors of Immunity | Journal of Clinical Immunology | 2018 | 732 |
| 31 | The avian Z-linked gene DMRT1 is required for male sex determination in the chicken | Nature | 2009 | 728 |
| 32 | Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature | Nature Genetics | 2012 | 712 |
| 33 | SWAN: Subset-quantile Within Array Normalization for Illumina Infinium HumanMethylation450 BeadChips | Genome Biology | 2012 | 697 |
| 34 | Global statistics on alcohol, tobacco and illicit drug use: 2017 status report | Addiction | 2018 | 685 |
| 35 | International Consensus Document (ICON): Common Variable Immunodeficiency Disorders | Journal of Allergy and Clinical Immunology: in Practice | 2016 | 669 |
| 36 | Pubertal transitions in health | Lancet, The | 2007 | 656 |
| 37 | Iron-Overload–Related Disease inHFEHereditary Hemochromatosis | New England Journal of Medicine | 2008 | 649 |
| 38 | Recommendations for the classification of group A rotaviruses using all 11 genomic RNA segments | Archives of Virology | 2008 | 642 |
| 39 | Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidney | Nature Cell Biology | 2014 | 640 |
| 40 | Adolescent resilience: a concept analysis | Journal of Adolescence | 2003 | 629 |
| 41 | Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium | Biological Psychiatry | 2018 | 627 |
| 42 | Splatter: simulation of single-cell RNA sequencing data | Genome Biology | 2017 | 626 |
| 43 | Primary Immunodeficiency Diseases: an Update on the Classification from the International Union of Immunological Societies Expert Committee for Primary Immunodeficiency 2015 | Journal of Clinical Immunology | 2015 | 621 |
| 44 | Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response | Nature Genetics | 2009 | 610 |
| 45 | Cerebral palsy | Nature Reviews Disease Primers | 2016 | 603 |
| 46 | Multiple Imputation for Missing Data: Fully Conditional Specification Versus Multivariate Normal Imputation | American Journal of Epidemiology | 2010 | 594 |
| 47 | Chest electrical impedance tomography examination, data analysis, terminology, clinical use and recommendations: consensus statement of the TRanslational EIT developmeNt stuDy group | Thorax | 2017 | 580 |
| 48 | Carcinoma Invasion and Metastasis: A Role for Epithelial-Mesenchymal Transition? | Cancer Research | 2005 | 579 |
| 49 | PerlPrimer: cross-platform, graphical primer design for standard, bisulphite and real-time PCR | Bioinformatics | 2004 | 575 |
| 50 | Nosology and classification of genetic skeletal disorders: 2010 revision | American Journal of Medical Genetics, Part A | 2011 | 573 |
