| # | Title | Journal | Year | Citations |
|---|
| 1 | Analysis of protein-coding genetic variation in 60,706 humans | Nature | 2016 | 9,051 |
| 2 | Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression | Nature Genetics | 2018 | 2,224 |
| 3 | Schizophrenia risk from complex variation of complement component 4 | Nature | 2016 | 1,915 |
| 4 | The Hierarchical Taxonomy of Psychopathology (HiTOP): A dimensional alternative to traditional nosologies. | Journal of Abnormal Psychology | 2017 | 1,804 |
| 5 | Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder | Nature Genetics | 2019 | 1,594 |
| 6 | Identification of common genetic risk variants for autism spectrum disorder | Nature Genetics | 2019 | 1,538 |
| 7 | De novo mutations in schizophrenia implicate synaptic networks | Nature | 2014 | 1,510 |
| 8 | HDAC2 negatively regulates memory formation and synaptic plasticity | Nature | 2009 | 1,414 |
| 9 | Genome-wide association analysis identifies 13 new risk loci for schizophrenia | Nature Genetics | 2013 | 1,395 |
| 10 | Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes | Immunity | 2019 | 1,351 |
| 11 | Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection | Nature Genetics | 2018 | 1,332 |
| 12 | A polygenic burden of rare disruptive mutations in schizophrenia | Nature | 2014 | 1,305 |
| 13 | Molecular Diversity and Specializations among the Cells of the Adult Mouse Brain | Cell | 2018 | 1,231 |
| 14 | Genome-wide association study identifies 30 loci associated with bipolar disorder | Nature Genetics | 2019 | 1,191 |
| 15 | Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder | Nature Genetics | 2008 | 1,102 |
| 16 | Analysis of shared heritability in common disorders of the brain | Science | 2018 | 1,085 |
| 17 | Cell diversity and network dynamics in photosensitive human brain organoids | Nature | 2017 | 933 |
| 18 | Mapping genomic loci implicates genes and synaptic biology in schizophrenia | Nature | 2022 | 929 |
| 19 | Single-Cell Multi-omic Integration Compares and Contrasts Features of Brain Cell Identity | Cell | 2019 | 844 |
| 20 | Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects | Nature Genetics | 2017 | 838 |
| 21 | De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia | Molecular Psychiatry | 2012 | 775 |
| 22 | An epigenetic blockade of cognitive functions in the neurodegenerating brain | Nature | 2012 | 733 |
| 23 | Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling | Cell | 2009 | 703 |
| 24 | Individual brain organoids reproducibly form cell diversity of the human cerebral cortex | Nature | 2019 | 649 |
| 25 | Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology | Nature Genetics | 2021 | 629 |
| 26 | Inhibitors of Class 1 Histone Deacetylases Reverse Contextual Memory Deficits in a Mouse Model of Alzheimer's Disease | Neuropsychopharmacology | 2010 | 627 |
| 27 | Addressing the burden of mental, neurological, and substance use disorders: key messages from Disease Control Priorities, 3rd edition | Lancet, The | 2016 | 586 |
| 28 | Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs | Nature Genetics | 2012 | 578 |
| 29 | Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases | American Journal of Human Genetics | 2014 | 569 |
| 30 | Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences | Nature Genetics | 2019 | 536 |
| 31 | SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse | Neuron | 2019 | 518 |
| 32 | Discovery and Statistical Genotyping of Copy-Number Variation from Whole-Exome Sequencing Depth | American Journal of Human Genetics | 2012 | 513 |
| 33 | Innovations and changes in the ICD‐11 classification of mental, behavioural and neurodevelopmental disorders | World Psychiatry | 2019 | 505 |
| 34 | Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders | Nature Neuroscience | 2018 | 490 |
| 35 | Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body β-hydroxybutyrate | ELife | 2016 | 475 |
| 36 | Comparative genetic architectures of schizophrenia in East Asian and European populations | Nature Genetics | 2019 | 440 |
| 37 | Increased burden of ultra-rare protein-altering variants among 4,877 individuals with schizophrenia | Nature Neuroscience | 2016 | 427 |
| 38 | Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations | Nature | 2017 | 409 |
| 39 | Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders | Nature Neuroscience | 2016 | 388 |
| 40 | Cyclin-dependent kinases: a family portrait | Nature Cell Biology | 2009 | 381 |
| 41 | Analysis of copy number variations at 15 schizophrenia-associated loci | British Journal of Psychiatry | 2014 | 380 |
| 42 | Largest GWAS of PTSD (N=20 070) yields genetic overlap with schizophrenia and sex differences in heritability | Molecular Psychiatry | 2018 | 374 |
| 43 | ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries | Translational Psychiatry | 2020 | 365 |
| 44 | International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci | Nature Communications | 2019 | 363 |
| 45 | Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair | Nature Genetics | 2015 | 357 |
| 46 | Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia | Molecular Psychiatry | 2014 | 333 |
| 47 | DSM-5 and RDoC: progress in psychiatry research? | Nature Reviews Neuroscience | 2013 | 326 |
| 48 | Rare coding variants in ten genes confer substantial risk for schizophrenia | Nature | 2022 | 326 |
| 49 | The Penetrance of Copy Number Variations for Schizophrenia and Developmental Delay | Biological Psychiatry | 2014 | 321 |
| 50 | Epigenetic Regulation of Gene Expression in Physiological and Pathological Brain Processes | Physiological Reviews | 2011 | 315 |
