| # | Title | Journal | Year | Citations |
|---|
| 1 | Ramucirumab plus docetaxel versus placebo plus docetaxel for second-line treatment of stage IV non-small-cell lung cancer after disease progression on platinum-based therapy (REVEL): a multicentre, double-blind, randomised phase 3 trial | Lancet, The | 2014 | 1,068 |
| 2 | International clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer | Journal of Thrombosis and Haemostasis | 2013 | 469 |
| 3 | Cell Adhesion Molecules: Role and Clinical Significance in Cancer | Cancer Investigation | 2009 | 280 |
| 4 | International clinical practice guidelines for the treatment and prophylaxis of thrombosis associated with central venous catheters in patients with cancer | Journal of Thrombosis and Haemostasis | 2013 | 252 |
| 5 | Pharmacological Agents Targeting Thromboinflammation in COVID-19: Review and Implications for Future Research | Thrombosis and Haemostasis | 2020 | 206 |
| 6 | Factors contributing to inappropriate ordering of tests in an academic medical department and the effect of an educational feedback strategy | Postgraduate Medical Journal | 2006 | 200 |
| 7 | The “Old” and the “New” Antibiotics for MDR Gram-Negative Pathogens: For Whom, When, and How | Frontiers in Public Health | 2019 | 198 |
| 8 | The Potential of Combined Immunotherapy and Antiangiogenesis for the Synergistic Treatment of Advanced NSCLC | Journal of Thoracic Oncology | 2017 | 186 |
| 9 | Multimorbidity care model: Recommendations from the consensus meeting of the Joint Action on Chronic Diseases and Promoting Healthy Ageing across the Life Cycle (JA-CHRODIS) | Health Policy | 2018 | 176 |
| 10 | Spatial Architecture and Arrangement of Tumor-Infiltrating Lymphocytes for Predicting Likelihood of Recurrence in Early-Stage Non–Small Cell Lung Cancer | Clinical Cancer Research | 2019 | 168 |
| 11 | Hypersensitivity Reactions Associated with Platinum Antineoplastic Agents: A Systematic Review | Metal-Based Drugs | 2010 | 153 |
| 12 | The role of mTOR in the management of solid tumors: An overview | Cancer Treatment Reviews | 2009 | 150 |
| 13 | Key molecular mechanisms in lung cancer invasion and metastasis: A comprehensive review | Critical Reviews in Oncology/Hematology | 2013 | 136 |
| 14 | The role of angiogenesis in solid tumours: An overview | European Journal of Internal Medicine | 2009 | 117 |
| 15 | Head and neck cancer in the elderly: An overview on the treatment modalities | Cancer Treatment Reviews | 2009 | 110 |
| 16 | The safety and efficacy of Onivyde (irinotecan liposome injection) for the treatment of metastatic pancreatic cancer following gemcitabine-based therapy | Expert Review of Anticancer Therapy | 2016 | 106 |
| 17 | Acute Pyelonephritis in Adults | Archives of Internal Medicine | 2003 | 100 |
| 18 | B7-H3 Expression in NSCLC and Its Association with B7-H4, PD-L1 and Tumor-Infiltrating Lymphocytes | Clinical Cancer Research | 2017 | 99 |
| 19 | Antimicrobial de-escalation in critically ill patients: a position statement from a task force of the European Society of Intensive Care Medicine (ESICM) and European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Critically Ill Patients Study Group (ESGCIP) | Intensive Care Medicine | 2020 | 97 |
| 20 | Anti-PD1/PDL1 induced psoriasis | Current Problems in Cancer | 2017 | 90 |
| 21 | The Biological Role of PI3K Pathway in Lung Cancer | Pharmaceuticals | 2012 | 89 |
| 22 | mTOR pathway: A current, up-to-date mini-review (Review) | Oncology Letters | 2014 | 87 |
| 23 | The VEGF pathway in lung cancer | Cancer Chemotherapy and Pharmacology | 2013 | 85 |
| 24 | Metachronous and Synchronous Primary Lung Cancers: Diagnostic Aspects, Surgical Treatment, and Prognosis | Clinical Lung Cancer | 2015 | 83 |
| 25 | Bevacizumab-Induced Hypertension | BioDrugs | 2011 | 81 |
| 26 | Phenotypes and Enviromental Factors: Their Influence in PCOS | Current Pharmaceutical Design | 2012 | 78 |
| 27 | Immune Marker Profiling and Programmed Death Ligand 1 Expression Across NSCLC Mutations | Journal of Thoracic Oncology | 2018 | 78 |
| 28 | Exhaled cysteinyl-leukotrienes and 8-isoprostane in patients with asthma and their relation to clinical severity | Respiratory Medicine | 2009 | 77 |
| 29 | Short‐term respiratory effects of e‐cigarettes in healthy individuals and smokers with asthma | Respirology | 2018 | 74 |
| 30 | Incidence and implications of chemotherapy related hand-foot syndrome | Expert Opinion on Drug Safety | 2016 | 73 |
| 31 | The significance of leptin, adiponectin, and resistin serum levels in non-small cell lung cancer (NSCLC) | Lung Cancer | 2008 | 69 |
| 32 | Targeted therapeutic approaches for hormone-refractory prostate cancer | Cancer Treatment Reviews | 2010 | 69 |
| 33 | Clinical significance of heat shock protein-70 expression in bladder cancer | Urology | 2003 | 68 |
| 34 | Wnt1 silences chemokine genes in dendritic cells and induces adaptive immune resistance in lung adenocarcinoma | Nature Communications | 2019 | 68 |
| 35 | A New Approach to Accurate Diagnosis of Acute Appendicitis | World Journal of Surgery | 2005 | 67 |
| 36 | Carboplatin Plus Pemetrexed as First-line Treatment of Patients With Malignant Pleural Mesothelioma: A Phase II Study | Clinical Lung Cancer | 2010 | 66 |
| 37 | Evaluation of serum lipids and high-density lipoprotein subfractions (HDL2, HDL3) in postmenopausal patients with breast cancer | Molecular and Cellular Biochemistry | 2005 | 65 |
| 38 | The intercellular cell adhesion molecule-1 (icam-1) in lung cancer: implications for disease progression and prognosis | Anticancer Research | 2014 | 63 |
| 39 | Hormones of adipose tissue and their biologic role in lung cancer | Cancer Treatment Reviews | 2014 | 61 |
| 40 | Quality of life and outcomes research in head and neck cancer: A review of the state of the discipline and likely future directions | Cancer Treatment Reviews | 2009 | 60 |
| 41 | A mortality prediction model in diabetic ketoacidosis | Clinical Endocrinology | 2002 | 59 |
| 42 | Clinical Significance of Smoking Cessation in Subjects With Cancer: A 30-Year Review | Respiratory Care | 2014 | 59 |
| 43 | Myofibroblasts and the progression of crescentic glomerulonephritis | Nephrology Dialysis Transplantation | 1998 | 57 |
| 44 | Bisphosphonate Use in Patients with Lung Cancer and Bone Metastases: Recommendations of a European Expert Panel | Journal of Thoracic Oncology | 2009 | 57 |
| 45 | Insulin resistance: an independent risk factor for lung cancer? | Metabolism: Clinical and Experimental | 2011 | 57 |
| 46 | XELIRI-bevacizumab versus FOLFIRI-bevacizumab as first-line treatment in patients with metastatic colorectal cancer: a Hellenic Cooperative Oncology Group phase III trial with collateral biomarker analysis | BMC Cancer | 2012 | 57 |
| 47 | The Role of E-Cadherin-Catenin Complex: More Than an Intercellular Glue? | Annals of Surgical Oncology | 2000 | 53 |
| 48 | Hypersensitivity reactions to antineoplastic agents: an overview | Anti-Cancer Drugs | 2009 | 53 |
| 49 | High expression of BCL-2 predicts favorable outcome in non-small cell lung cancer patients with non squamous histology | BMC Cancer | 2010 | 53 |
| 50 | Developing definitions for invasive fungal diseases in critically ill adult patients in intensive care units. Protocol of the FUNgal infections Definitions in ICU patients (FUNDICU) project | Mycoses | 2019 | 53 |
