| # | Title | Journal | Year | Citations |
|---|
| 1 | Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums | Nature Reviews Neurology | 2018 | 905 |
| 2 | Altered neuregulin 1–erbB4 signaling contributes to NMDA> receptor hypofunction in schizophrenia | Nature Medicine | 2006 | 528 |
| 3 | HALYs and QALYs and DALYs, Oh My: Similarities and Differences in Summary Measures of Population Health | Annual Review of Public Health | 2002 | 467 |
| 4 | The dual role of iNOS in cancer | Redox Biology | 2015 | 397 |
| 5 | Sociodemographics, self-rated health, and mortality in the US | Social Science and Medicine | 2003 | 378 |
| 6 | Do sterols reduce proton and sodium leaks through lipid bilayers? | Progress in Lipid Research | 2001 | 332 |
| 7 | Toward Consistency in Cost-Utility Analyses | Medical Care | 1998 | 326 |
| 8 | Sex/gender differences in smoking cessation: A review | Preventive Medicine | 2016 | 286 |
| 9 | Coronary artery spasm | Biochemical Pharmacology | 1995 | 279 |
| 10 | Biology and therapeutic potential of hydrogen sulfide and hydrogen sulfide-releasing chimeras | Biochemical Pharmacology | 2013 | 270 |
| 11 | Artemisinin (qinghaosu): the role of intracellular hemin in its mechanism of antimalarial action | Molecular and Biochemical Parasitology | 1991 | 268 |
| 12 | Ethanol Consumption Inhibits Fetal DNA Methylation in Mice: Implications for the Fetal Alcohol Syndrome | Alcoholism: Clinical and Experimental Research | 1991 | 246 |
| 13 | A practical guide for induction of type-2 diabetes in rat: Incorporating a high-fat diet and streptozotocin | Biomedicine and Pharmacotherapy | 2017 | 210 |
| 14 | Sleep-Dependent Improvement in Visuomotor Learning: A Causal Role for Slow Waves | Sleep | 2009 | 200 |
| 15 | Local Experience-Dependent Changes in the Wake EEG after Prolonged Wakefulness | Sleep | 2013 | 178 |
| 16 | Mammalian Spermatogenesisin Vivoandin Vitro: A Partnership of Spermatogenic and Somatic Cell Lineages* | Endocrine Reviews | 1994 | 171 |
| 17 | The granular convoluted tubule (GCT) cell of rodent submandibular glands | Microscopy Research and Technique | 1994 | 159 |
| 18 | Ultra-low-dose naloxone suppresses opioid tolerance, dependence and associated changes in mu opioid receptor–G protein coupling and Gβγ signaling | Neuroscience | 2005 | 158 |
| 19 | In vitro and in vivo inhibitory effect of ethanol and acetaldehyde on O6-methylguanine transferase | Carcinogenesis | 1988 | 156 |
| 20 | NOSH-Aspirin: A Novel Nitric Oxide–Hydrogen Sulfide-Releasing Hybrid: A New Class of Anti-inflammatory Pharmaceuticals | ACS Medicinal Chemistry Letters | 2012 | 147 |
| 21 | Hemin-catalyzed decomposition of artemisinin (qinghaosu) | Biochemical Pharmacology | 1992 | 144 |
| 22 | Nitric oxide synthase in motor neurons after axotomy. | Journal of Histochemistry and Cytochemistry | 1994 | 142 |
| 23 | Alcohol and Cancer | Annual Review of Pharmacology and Toxicology | 1990 | 140 |
| 24 | Distinct changes in cortical and spinal excitability following high-frequency repetitive TMS to the human motor cortex | Experimental Brain Research | 2005 | 140 |
| 25 | Nitric-oxide-donating NSAIDs as agents for cancer prevention | Trends in Molecular Medicine | 2004 | 139 |
| 26 | Intensive Rehabilitation Treatment in Early Parkinson’s Disease | Neurorehabilitation and Neural Repair | 2015 | 137 |
| 27 | American Opiophobia: | Advances in Alcohol & Substance Abuse | 1985 | 130 |
| 28 | SKF83959 selectively regulates phosphatidylinositol‐linked D1 dopamine receptors in rat brain | Journal of Neurochemistry | 2003 | 129 |
| 29 | Methodological concerns and recommendations on policy consequences of the World Health Report 2000 | Lancet, The | 2001 | 122 |
| 30 | Nitric oxide-donating aspirin inhibits -catenin/T cell factor (TCF) signaling in SW480 colon cancer cells by disrupting the nuclear -catenin-TCF association | Proceedings of the National Academy of Sciences of the United States of America | 2003 | 115 |
| 31 | Hydrogen sulfide-releasing NSAIDs inhibit the growth of human cancer cells: A general property and evidence of a tissue type-independent effect | Biochemical Pharmacology | 2012 | 114 |
| 32 | NOSH–aspirin (NBS-1120), a novel nitric oxide- and hydrogen sulfide-releasing hybrid is a potent inhibitor of colon cancer cell growth in vitro and in a xenograft mouse model | Biochemical and Biophysical Research Communications | 2012 | 113 |
| 33 | Toward a Consensus on the QALY | Value in Health | 2009 | 112 |
| 34 | Mapping the SF-12 to the EuroQol EQ-5D Index in a National US Sample | Medical Decision Making | 2004 | 110 |
| 35 | The ERK-1/2 Signaling Pathway Is Involved in the Stimulation of Branching Morphogenesis of Fetal Mouse Submandibular Glands by EGF | Developmental Biology | 2000 | 109 |
| 36 | Neural and Behavioral Correlates of Extended Training during Sleep Deprivation in Humans: Evidence for Local, Task-Specific Effects | Journal of Neuroscience | 2015 | 108 |
| 37 | The nature, significance, and glucagon‐like peptide‐1 analog treatment of brain insulin resistance in Alzheimer's disease | Alzheimer's and Dementia | 2014 | 106 |
| 38 | Identification and Characterization of a Stereospecific Human Enzyme That Catalyzes 9-cis-Retinol Oxidation | Journal of Biological Chemistry | 1997 | 99 |
| 39 | Increased cerebellar activation during sequence learning in DYT1 carriers: an equiperformance study | Brain | 2007 | 99 |
| 40 | Dissociating -Amyloid from 7 Nicotinic Acetylcholine Receptor by a Novel Therapeutic Agent, S 24795, Normalizes 7 Nicotinic Acetylcholine and NMDA Receptor Function in Alzheimer's Disease Brain | Journal of Neuroscience | 2009 | 97 |
| 41 | Equalization of four cardiovascular risk algorithms after systematic recalibration: individual-participant meta-analysis of 86 prospective studies | European Heart Journal | 2019 | 97 |
| 42 | Non-COX-2 targets and cancer: Expanding the molecular target repertoire of chemoprevention | Biochemical Pharmacology | 2005 | 96 |
| 43 | Barriers to and Facilitators of Help-Seeking Behavior Among Men Who Experience Sexual Violence | American Journal of Men's Health | 2018 | 96 |
| 44 | Administration of testosterone attenuates neuronal loss following axotomy in the brain-stem motor nuclei of female rats | Journal of Neuroscience | 1989 | 94 |
| 45 | Cholinergic constriction in the general circulation and its role in coronary artery spasm. | Circulation Research | 1989 | 93 |
| 46 | The burden of disease associated with being African-American in the United States and the contribution of socio-economic status | Social Science and Medicine | 2006 | 92 |
| 47 | Control of species-dependent cortico-motoneuronal connections underlying manual dexterity | Science | 2017 | 92 |
| 48 | Modulation of Gamma and Theta Spectral Amplitude and Phase Synchronization Is Associated with the Development of Visuo-Motor Learning | Journal of Neuroscience | 2011 | 90 |
| 49 | Community-Oriented Primary Care: A Path to Community Development | American Journal of Public Health | 2002 | 88 |
| 50 | Epidermal growth factor system is a physiological regulator of development of the mouse fetal submandibular gland and regulates expression of the α6-integrin subunit | | 1997 | 84 |
