| # | Title | Journal | Year | Citations |
|---|
| 1 | Prevalence of chronic kidney disease in China: a cross-sectional survey | Lancet, The | 2012 | 1,643 |
| 2 | The methodological quality assessment tools for preclinical and clinical studies, systematic review and meta‐analysis, and clinical practice guideline: a systematic review | Journal of Evidence-Based Medicine | 2015 | 1,366 |
| 3 | Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open label, randomised controlled trial | BMJ, The | 2020 | 811 |
| 4 | Immune cells within the tumor microenvironment: Biological functions and roles in cancer immunotherapy | Cancer Letters | 2020 | 753 |
| 5 | Direct Z-scheme ZnO/CdS hierarchical photocatalyst for enhanced photocatalytic H2-production activity | Applied Catalysis B: Environmental | 2019 | 653 |
| 6 | Composition and divergence of coronavirus spike proteins and host ACE2 receptors predict potential intermediate hosts of SARS‐CoV‐2 | Journal of Medical Virology | 2020 | 546 |
| 7 | Clinical characteristics, outcomes, and risk factors for mortality in patients with cancer and COVID-19 in Hubei, China: a multicentre, retrospective, cohort study | Lancet Oncology, The | 2020 | 447 |
| 8 | Deletion of aquaporin-4 in APP/PS1 mice exacerbates brain Aβ accumulation and memory deficits | Molecular Neurodegeneration | 2015 | 322 |
| 9 | A Novel Gene Signature-Based Model Predicts Biochemical Recurrence-Free Survival in Prostate Cancer Patients after Radical Prostatectomy | Cancers | 2020 | 300 |
| 10 | Recent advances in g-C3N4-based heterojunction photocatalysts | Journal of Materials Science and Technology | 2020 | 297 |
| 11 | Photocatalytic H2 evolution on graphdiyne/g-C3N4 hybrid nanocomposites | Applied Catalysis B: Environmental | 2019 | 284 |
| 12 | Molecular pathogenesis of Klebsiella pneumoniae | Future Microbiology | 2014 | 247 |
| 13 | VEGF/SDF-1 promotes cardiac stem cell mobilization and myocardial repair in the infarcted heart | Cardiovascular Research | 2011 | 223 |
| 14 | Sleep duration and risk of all-cause mortality: A flexible, non-linear, meta-regression of 40 prospective cohort studies | Sleep Medicine Reviews | 2017 | 212 |
| 15 | Role of RAGE in Alzheimer’s Disease | Cellular and Molecular Neurobiology | 2016 | 203 |
| 16 | The mental health of frontline and non-frontline medical workers during the coronavirus disease 2019 (COVID-19) outbreak in China: A case-control study | Journal of Affective Disorders | 2020 | 192 |
| 17 | Predicting 30-days mortality for MIMIC-III patients with sepsis-3: a machine learning approach using XGboost | Journal of Translational Medicine | 2020 | 175 |
| 18 | Combined lifestyle factors and risk of incident type 2 diabetes and prognosis among individuals with type 2 diabetes: a systematic review and meta-analysis of prospective cohort studies | Diabetologia | 2020 | 172 |
| 19 | A Genome-Wide Association Study Identifies GRK5 and RASGRP1 as Type 2 Diabetes Loci in Chinese Hans | Diabetes | 2013 | 166 |
| 20 | Chrysin enhances sensitivity of BEL-7402/ADM cells to doxorubicin by suppressing PI3K/Akt/Nrf2 and ERK/Nrf2 pathway | Chemico-Biological Interactions | 2013 | 157 |
| 21 | Three-dimensional carbon foam supported MnO2/Pt for rapid capture and catalytic oxidation of formaldehyde at room temperature | Applied Catalysis B: Environmental | 2020 | 147 |
| 22 | Apigenin sensitizes doxorubicin-resistant hepatocellular carcinoma BEL-7402/ADM cells to doxorubicin via inhibiting PI3K/Akt/Nrf2 pathway | Carcinogenesis | 2013 | 145 |
| 23 | TM4SF1 promotes EMT and cancer stemness via the Wnt/β-catenin/SOX2 pathway in colorectal cancer | Journal of Experimental and Clinical Cancer Research | 2020 | 144 |
| 24 | Extracellular vesicles in diagnosis and therapy of kidney diseases | American Journal of Physiology - Renal Physiology | 2016 | 140 |
| 25 | RNA Interference-Induced Innate Immunity, Off-Target Effect, or Immune Adjuvant? | Frontiers in Immunology | 2017 | 140 |
| 26 | Online photochemical derivatization enables comprehensive mass spectrometric analysis of unsaturated phospholipid isomers | Nature Communications | 2019 | 133 |
| 27 | Evasion of host antiviral innate immunity by HSV-1, an update | Virology Journal | 2016 | 131 |
| 28 | Plasma Metal Concentrations and Incident Coronary Heart Disease in Chinese Adults: The Dongfeng-Tongji Cohort | Environmental Health Perspectives | 2017 | 131 |
| 29 | LncRNA SNHG12 promotes tumorigenesis and metastasis in osteosarcoma by upregulating Notch2 by sponging miR-195-5p | Biochemical and Biophysical Research Communications | 2018 | 126 |
| 30 | Competing endogenous RNA interplay in cancer: mechanism, methodology, and perspectives | Tumor Biology | 2015 | 121 |
| 31 | Strigolactone‐triggered stomatal closure requires hydrogen peroxide synthesis and nitric oxide production in an abscisic acid‐independent manner | New Phytologist | 2018 | 121 |
| 32 | Role of berberine in Alzheimer’s disease | Neuropsychiatric Disease and Treatment | 2016 | 120 |
| 33 | Adjuvant treatment strategies in ovarian stimulation for poor responders undergoing IVF: a systematic review and network meta-analysis | Human Reproduction Update | 2020 | 120 |
| 34 | Activation of the miR-34a-Mediated SIRT1/mTOR Signaling Pathway by Urolithin A Attenuates d-Galactose-Induced Brain Aging in Mice | Neurotherapeutics | 2019 | 118 |
| 35 | Risk factors for adverse clinical outcomes with COVID-19 in China: a multicenter, retrospective, observational study | Theranostics | 2020 | 117 |
| 36 | Large-scale lipid analysis with C=C location and sn-position isomer resolving power | Nature Communications | 2020 | 117 |
| 37 | Is shift work associated with a higher risk of overweight or obesity? A systematic review of observational studies with meta-analysis | International Journal of Epidemiology | 2018 | 116 |
| 38 | Role of SCFAs in gut microbiome and glycolysis for colorectal cancer therapy | Journal of Cellular Physiology | 2019 | 116 |
| 39 | The Comparation of Intraperitoneal Injection and Nasal-only Delivery Allergic Rhinitis Model Challenged With Different Allergen Concentration | American Journal of Rhinology and Allergy | 2019 | 113 |
| 40 | XueBiJing Injection Versus Placebo for Critically Ill Patients With Severe Community-Acquired Pneumonia: A Randomized Controlled Trial | Critical Care Medicine | 2019 | 112 |
| 41 | Antioxidative, anti-inflammatory and anti-apoptotic effects of ellagic acid in liver and brain of rats treated by D-galactose | Scientific Reports | 2018 | 111 |
| 42 | Interleukin-17 acts as double-edged sword in anti-tumor immunity and tumorigenesis | Cytokine | 2017 | 108 |
| 43 | A light-regulated host–guest-based nanochannel system inspired by channelrhodopsins protein | Nature Communications | 2017 | 108 |
| 44 | Hsa-miR-139-5p inhibits proliferation and causes apoptosis associated with down-regulation of c-Met | Oncotarget | 2015 | 107 |
| 45 | Therapeutic potential of CAR-T cell-derived exosomes: a cell-free modality for targeted cancer therapy | Oncotarget | 2015 | 106 |
| 46 | A deep-learning pipeline for the diagnosis and discrimination of viral, non-viral and COVID-19 pneumonia from chest X-ray images | Nature Biomedical Engineering | 2021 | 106 |
| 47 | Global injury morbidity and mortality from 1990 to 2017: results from the Global Burden of Disease Study 2017 | Injury Prevention | 2020 | 103 |
| 48 | CLE9 peptide‐induced stomatal closure is mediated by abscisic acid, hydrogen peroxide, and nitric oxide in Arabidopsis thaliana | Plant, Cell and Environment | 2019 | 101 |
| 49 | Patient-reported Outcomes of Patients With Breast Cancer During the COVID-19 Outbreak in the Epicenter of China: A Cross-sectional Survey Study | Clinical Breast Cancer | 2020 | 101 |
| 50 | Interleukin-8 as a Biomarker for Disease Prognosis of Coronavirus Disease-2019 Patients | Frontiers in Immunology | 2020 | 101 |
