| # | Title | Journal | Year | Citations |
|---|
| 1 | The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1 | Nature Cell Biology | 2008 | 3,455 |
| 2 | Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009 | Cell Death and Differentiation | 2009 | 2,572 |
| 3 | Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012 | Cell Death and Differentiation | 2012 | 2,144 |
| 4 | A family of cytokine-inducible inhibitors of signalling | Nature | 1997 | 1,947 |
| 5 | A Double-Negative Feedback Loop between ZEB1-SIP1 and the microRNA-200 Family Regulates Epithelial-Mesenchymal Transition | Cancer Research | 2008 | 956 |
| 6 | Physiological functions of the HECT family of ubiquitin ligases | Nature Reviews Molecular Cell Biology | 2009 | 888 |
| 7 | International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data | Blood | 2022 | 814 |
| 8 | Cholesteryl Ester Transfer Protein | Arteriosclerosis, Thrombosis, and Vascular Biology | 2003 | 780 |
| 9 | The Human Mitochondrial Transcriptome | Cell | 2011 | 716 |
| 10 | Caspase function in programmed cell death | Cell Death and Differentiation | 2007 | 711 |
| 11 | Long-term benefits and risks of frontline nilotinib vs imatinib for chronic myeloid leukemia in chronic phase: 5-year update of the randomized ENESTnd trial | Leukemia | 2016 | 685 |
| 12 | The Biology and Clinical Uses of Blood Stem Cells | Blood | 1997 | 663 |
| 13 | Safety and efficacy of imatinib cessation for CML patients with stable undetectable minimal residual disease: results from the TWISTER study | Blood | 2013 | 641 |
| 14 | Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes | Cell Death and Differentiation | 2009 | 599 |
| 15 | Osteal Tissue Macrophages Are Intercalated throughout Human and Mouse Bone Lining Tissues and Regulate Osteoblast Function In Vitro and In Vivo | Journal of Immunology | 2008 | 597 |
| 16 | The STRO-1+ fraction of adult human bone marrow contains the osteogenic precursors | Blood | 1994 | 588 |
| 17 | Refining analyses of copy number variation identifies specific genes associated with developmental delay | Nature Genetics | 2014 | 583 |
| 18 | Immune Activation in Patients With Irritable Bowel Syndrome | Gastroenterology | 2007 | 561 |
| 19 | A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation | Nature Genetics | 2009 | 528 |
| 20 | Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia | Nature Genetics | 2011 | 524 |
| 21 | Periodontal Ligament Stem Cell-Mediated Treatment for Periodontitis in Miniature Swine | Stem Cells | 2008 | 516 |
| 22 | The biology of stem cell factor and its receptor C-kit | International Journal of Biochemistry and Cell Biology | 1999 | 510 |
| 23 | An autocrine TGF-β/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition | Molecular Biology of the Cell | 2011 | 505 |
| 24 | Experimental strategies for microRNA target identification | Nucleic Acids Research | 2011 | 493 |
| 25 | Activation of sphingosine kinase 1 by ERK1/2-mediated phosphorylation | EMBO Journal | 2003 | 484 |
| 26 | MicroRNAs as regulators of epithelial-mesenchymal transition | Cell Cycle | 2008 | 467 |
| 27 | Identification and isolation of candidate human keratinocyte stem cells based on cell surface phenotype | Proceedings of the National Academy of Sciences of the United States of America | 1998 | 451 |
| 28 | Angiopoietin-1 Is an Antipermeability and Anti-Inflammatory Agent In Vitro and Targets Cell Junctions | Circulation Research | 2000 | 450 |
| 29 | Nilotinib versus imatinib for the treatment of patients with newly diagnosed chronic phase, Philadelphia chromosome-positive, chronic myeloid leukaemia: 24-month minimum follow-up of the phase 3 randomised ENESTnd trial | Lancet Oncology, The | 2011 | 444 |
| 30 | Long-term prognostic significance of early molecular response to imatinib in newly diagnosed chronic myeloid leukemia: an analysis from the International Randomized Study of Interferon and STI571 (IRIS) | Blood | 2010 | 440 |
| 31 | A circRNA from SEPALLATA3 regulates splicing of its cognate mRNA through R-loop formation | Nature Plants | 2017 | 434 |
| 32 | Sclerostin Stimulates Osteocyte Support of Osteoclast Activity by a RANKL-Dependent Pathway | PLoS ONE | 2011 | 419 |
| 33 | IsomiRs – the overlooked repertoire in the dynamic microRNAome | Trends in Genetics | 2012 | 410 |
| 34 | Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells | Nature Immunology | 2013 | 410 |
| 35 | Nilotinib vs imatinib in patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase: ENESTnd 3-year follow-up | Leukemia | 2012 | 395 |
| 36 | An oncogenic role of sphingosine kinase | Current Biology | 2000 | 392 |
| 37 | Stillbirths: the way forward in high-income countries | Lancet, The | 2011 | 389 |
| 38 | The allosteric inhibitor ABL001 enables dual targeting of BCR–ABL1 | Nature | 2017 | 389 |
| 39 | Early molecular and cytogenetic response is predictive for long-term progression-free and overall survival in chronic myeloid leukemia (CML) | Leukemia | 2012 | 383 |
| 40 | International Randomized Study of Interferon Vs STI571 (IRIS) 8-Year Follow up: Sustained Survival and Low Risk for Progression or Events in Patients with Newly Diagnosed Chronic Myeloid Leukemia in Chronic Phase (CML-CP) Treated with Imatinib. | Blood | 2009 | 358 |
| 41 | ICE-like proteases in apoptosis | Trends in Biochemical Sciences | 1995 | 357 |
| 42 | Functions and effectors of the Salmonella pathogenicity island 2 type III secretion system | Cellular Microbiology | 2003 | 354 |
| 43 | B cell–intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans | Journal of Experimental Medicine | 2010 | 346 |
| 44 | Nilotinib is effective in patients with chronic myeloid leukemia in chronic phase after imatinib resistance or intolerance: 24-month follow-up results | Blood | 2011 | 344 |
| 45 | Thrombosis: a major contributor to the global disease burden | Journal of Thrombosis and Haemostasis | 2014 | 343 |
| 46 | Stromal-derived factor-1 promotes the growth, survival, and development of human bone marrow stromal stem cells | Blood | 2005 | 341 |
| 47 | Autophagy, Not Apoptosis, Is Essential for Midgut Cell Death in Drosophila | Current Biology | 2009 | 337 |
| 48 | AUUUA is not sufficient to promote poly(A) shortening and degradation of an mRNA: the functional sequence within AU-rich elements may be UUAUUUA(U/A)(U/A). | Molecular and Cellular Biology | 1994 | 334 |
| 49 | Cell death by autophagy: facts and apparent artefacts | Cell Death and Differentiation | 2012 | 334 |
| 50 | Electrophysiological, Electroanatomical, and Structural Remodeling of the Atria as Consequences of Sustained Obesity | Journal of the American College of Cardiology | 2015 | 331 |
