| # | Title | Journal | Year | Citations |
|---|
| 1 | Clopidogrel and Aspirin versus Aspirin Alone for the Prevention of Atherothrombotic Events | New England Journal of Medicine | 2006 | 2,582 |
| 2 | Dietary effects on breast-cancer risk in Singapore | Lancet, The | 1991 | 715 |
| 3 | Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific Association for the study of the liver (APASL) | Hepatology International | 2009 | 709 |
| 4 | Increased rectal mucosal expression of interleukin 1beta in recently acquired post-infectious irritable bowel syndrome | Gut | 2003 | 350 |
| 5 | Criterion-based validity and reliability of the Geriatric Depression Screening Scale (GDS-15) in a large validation sample of community-living Asian older adults | Aging and Mental Health | 2009 | 316 |
| 6 | IL-7 Licenses Activation of Human Liver Intrasinusoidal Mucosal-Associated Invariant T Cells | Journal of Immunology | 2013 | 298 |
| 7 | Characteristics and outcomes of culture-negative versus culture-positive severe sepsis | Critical Care | 2013 | 250 |
| 8 | Inflammatory tumour microenvironment is associated with superior survival in hepatocellular carcinoma patients | Journal of Hepatology | 2010 | 227 |
| 9 | Profile of Tumor Antigen-Specific CD8 T Cells in Patients With Hepatitis B Virus-Related Hepatocellular Carcinoma | Gastroenterology | 2009 | 152 |
| 10 | Efficacy, safety, and immunogenicity of the human papillomavirus 16/18 AS04-adjuvanted vaccine in women older than 25 years: 7-year follow-up of the phase 3, double-blind, randomised controlled VIVIANE study | Lancet Infectious Diseases, The | 2016 | 148 |
| 11 | Asian consensus on irritable bowel syndrome | Journal of Gastroenterology and Hepatology (Australia) | 2010 | 141 |
| 12 | Drug-induced liver injury at an Asian center: a prospective study | Liver International | 2007 | 128 |
| 13 | Growth differentiation factor 15 in heart failure with preserved vs. reduced ejection fraction | European Journal of Heart Failure | 2016 | 128 |
| 14 | The Gut Microbiota and Irritable Bowel Syndrome: Friend or Foe? | International Journal of Inflammation | 2012 | 121 |
| 15 | Iron deficiency in a multi‐ethnic Asian population with and without heart failure: prevalence, clinical correlates, functional significance and prognosis | European Journal of Heart Failure | 2014 | 104 |
| 16 | Prevalence of Healthcare-Associated Infections and Antimicrobial Use Among Adult Inpatients in Singapore Acute-Care Hospitals: Results From the First National Point Prevalence Survey | Clinical Infectious Diseases | 2017 | 97 |
| 17 | IgM in human immunity to Plasmodium falciparum malaria | Science Advances | 2019 | 92 |
| 18 | Fundamental Concepts Regarding Testosterone Deficiency and Treatment | Mayo Clinic Proceedings | 2016 | 88 |
| 19 | Heart block and empirical therapy after transcatheter closure of perimembranous ventricular septal defect | Catheterization and Cardiovascular Interventions | 2005 | 87 |
| 20 | Rescue ICSI of oocytes that failed to extrude the second polar body 6 h post-insemination in conventional IVF | Human Reproduction | 2003 | 86 |
| 21 | Short coincubation of gametes in in vitro fertilization improves implantation and pregnancy rates: a prospective, randomized, controlled study | Fertility and Sterility | 2003 | 82 |
| 22 | Bugs and irritable bowel syndrome: The good, the bad and the ugly | Journal of Gastroenterology and Hepatology (Australia) | 2010 | 75 |
| 23 | Effect of Clopidogrel plus ASA vs. ASA Early after TIA and Ischaemic Stroke: A Substudy of the CHARISMA Trial | International Journal of Stroke | 2011 | 73 |
| 24 | Nonsteroidal anti-inflammatory drugs in chronic pain: implications of new data for clinical practice | Journal of Pain Research | 2018 | 72 |
| 25 | Prevention and management of vision loss relating to facial filler injections | Singapore Medical Journal | 2016 | 70 |
| 26 | Expert recommendations for the diagnosis and treatment of iron-deficiency anemia during pregnancy and the postpartum period in the Asia-Pacific region | Journal of Perinatal Medicine | 2011 | 67 |
| 27 | Reverse Remodeling and Prognosis Following Kidney Transplantation in Contemporary Patients With Cardiac Dysfunction | Journal of the American College of Cardiology | 2015 | 66 |
| 28 | A randomized controlled pilot study of Pentoxifylline in patients with non-alcoholic steatohepatitis (NASH) | Hepatology International | 2008 | 64 |
| 29 | Laparoscopic dismembered pyeloplasty in children: preliminary results | BJU International | 1996 | 63 |
| 30 | Management of endometrial cancer in Asia: consensus statement from the Asian Oncology Summit 2009 | Lancet Oncology, The | 2009 | 62 |
| 31 | Coprescribing proton-pump inhibitors with nonsteroidal anti-inflammatory drugs: risks versus benefits | Journal of Pain Research | 2018 | 61 |
| 32 | Natural Human Infections With Plasmodium cynomolgi and Other Malaria Species in an Elimination Setting in Sabah, Malaysia | Journal of Infectious Diseases | 2019 | 61 |
| 33 | Updates on malaria incidence and profile in Malaysia from 2013 to 2017 | Malaria Journal | 2020 | 60 |
| 34 | Intrahepatic CD206+ macrophages contribute to inflammation in advanced viral-related liver disease | Journal of Hepatology | 2017 | 55 |
| 35 | Preserved foods and nasopharyngeal carcinoma: A case-control study among singapore chinese | International Journal of Cancer | 1994 | 51 |
| 36 | Heart Failure Clinical Trials in East and Southeast Asia | JACC: Heart Failure | 2016 | 48 |
| 37 | Case Report: A Case of Fish Bone Perforation of the Stomach Mimicking a Locally Advanced Pancreatic Carcinoma | Digestive Diseases and Sciences | 2004 | 47 |
| 38 | In vivo performance of implantable biodegradable preparations delivering Paclitaxel and Etanidazole for the treatment of glioma | Biomaterials | 2007 | 47 |
| 39 | A prospective study of the clinical features, manometric findings, incidence and prevalence of achalasia in Singapore | Journal of Gastroenterology and Hepatology (Australia) | 1999 | 42 |
| 40 | Functional dyspepsia and irritable bowel syndrome, are they different entities and does it matter | World Journal of Gastroenterology | 2006 | 39 |
| 41 | Interaction between warfarin and Chinese herbal medicines | Singapore Medical Journal | 2015 | 37 |
| 42 | The Effects of Sleeve Gastrectomy and Gastric Bypass on Branched-Chain Amino Acid Metabolism 1 Year After Bariatric Surgery | Obesity Surgery | 2016 | 37 |
| 43 | Stress-coping morbidity among family members of addiction patients in Singapore | Drug and Alcohol Review | 2011 | 36 |
| 44 | Risk of gonadoblastoma in female patients with Y chromosome abnormalities and dysgenetic gonads | Journal of Paediatrics and Child Health | 1999 | 34 |
| 45 | Herbal medicine in the treatment of functional gastrointestinal disorders: A systematic review with meta‐analysis | Journal of Gastroenterology and Hepatology (Australia) | 2020 | 34 |
| 46 | Real-world experience of first-line afatinib in patients with EGFR-mutant advanced NSCLC: a multicenter observational study | BMC Cancer | 2019 | 33 |
| 47 | A call to arms: a perspective on safe general surgery in Singapore during the COVID-19 pandemic | Singapore Medical Journal | 2020 | 33 |
| 48 | Comparison of pronuclear zygote morphology and early cleavage status of zygotes as additional criteria in the selection of day 3 embryos: a randomized study | Fertility and Sterility | 2006 | 28 |
| 49 | Role of metformin in the initiation of pharmacotherapy for type 2 diabetes: An Asian-Pacific perspective | Diabetes Research and Clinical Practice | 2007 | 28 |
| 50 | Cardiovascular Disease Risk in a Semirural Community in Malaysia | Asia-Pacific Journal of Public Health | 2009 | 28 |
