| # | Title | Journal | Year | Citations |
|---|
| 1 | Classification of acute pancreatitis—2012: revision of the Atlanta classification and definitions by international consensus | Gut | 2013 | 4,813 |
| 2 | Nivolumab plus Ipilimumab in Lung Cancer with a High Tumor Mutational Burden | New England Journal of Medicine | 2018 | 2,469 |
| 3 | Primary biliary cirrhosis | Hepatology | 2009 | 1,020 |
| 4 | Long-term Therapy With Adefovir Dipivoxil for HBeAg-Negative Chronic Hepatitis B for up to 5 Years | Gastroenterology | 2006 | 832 |
| 5 | Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer | Lancet Oncology, The | 2008 | 709 |
| 6 | Clinical outcome of protocol based image (MRI) guided adaptive brachytherapy combined with 3D conformal radiotherapy with or without chemotherapy in patients with locally advanced cervical cancer | Radiotherapy and Oncology | 2011 | 649 |
| 7 | Technical report: ethical and policy issues in genetic testing and screening of children | Genetics in Medicine | 2013 | 389 |
| 8 | Prevalence of psoriatic arthritis in patients with psoriasis: A systematic review and meta-analysis of observational and clinical studies | Journal of the American Academy of Dermatology | 2019 | 362 |
| 9 | Recommendations from Gynaecological (GYN) GEC-ESTRO Working Group (IV): Basic principles and parameters for MR imaging within the frame of image based adaptive cervix cancer brachytherapy | Radiotherapy and Oncology | 2012 | 342 |
| 10 | Missed Opportunities: Racial Disparities in Adjuvant Breast Cancer Treatment | Journal of Clinical Oncology | 2006 | 333 |
| 11 | Taxane resistance in breast cancer: Mechanisms, predictive biomarkers and circumvention strategies | Cancer Treatment Reviews | 2012 | 221 |
| 12 | Somatic EGFR mutations and efficacy of tyrosine kinase inhibitors in NSCLC | Nature Reviews Clinical Oncology | 2009 | 207 |
| 13 | Trastuzumab in the Adjuvant Treatment of Early-Stage Breast Cancer: A Systematic Review and Meta-Analysis of Randomized Controlled Trials | Oncologist | 2008 | 205 |
| 14 | Combination of Bisphosphonates and Antiangiogenic Factors Induces Osteonecrosis of the Jaw More Frequently than Bisphosphonates Alone | Oncology | 2009 | 203 |
| 15 | The dermatopathology of Cowden's syndrome* | British Journal of Dermatology | 1979 | 181 |
| 16 | First-Line Nivolumab Plus Ipilimumab in Advanced NSCLC: 4-Year Outcomes From the Randomized, Open-Label, Phase 3 CheckMate 227 Part 1 Trial | Journal of Thoracic Oncology | 2022 | 173 |
| 17 | Subacute sclerosing panencephalitis: an update | Developmental Medicine and Child Neurology | 2010 | 163 |
| 18 | Dual neutralization of both interleukin 17A and interleukin 17F with bimekizumab in patients with psoriasis: Results from BE ABLE 1, a 12-week randomized, double-blinded, placebo-controlled phase 2b trial | Journal of the American Academy of Dermatology | 2018 | 163 |
| 19 | Rates and types of psychiatric disorders in perinatally human immunodeficiency virus‐infected youth and seroreverters | Journal of Child Psychology and Psychiatry and Allied Disciplines | 2009 | 157 |
| 20 | The treatment of brain metastases in melanoma patients | Cancer Treatment Reviews | 2004 | 144 |
| 21 | Successful Reperfusion With Intravenous Thrombolysis Preceding Mechanical Thrombectomy in Large-Vessel Occlusions | Stroke | 2018 | 141 |
| 22 | Blood Pressure Reduction and Secondary Stroke Prevention | Hypertension | 2017 | 140 |
| 23 | Azathioprine Is Superior to Budesonide in Achieving and Maintaining Mucosal Healing and Histologic Remission in Steroid-Dependent Crohnʼs Disease | Inflammatory Bowel Diseases | 2009 | 139 |
| 24 | Somatic Mutations of the Tyrosine Kinase Domain of Epidermal Growth Factor Receptor and Tyrosine Kinase Inhibitor Response to TKIs in Non-small Cell Lung Cancer: An Analytical Database | Journal of Thoracic Oncology | 2008 | 137 |
| 25 | Complications and recurrences associated with laparoscopic repair of groin hernias | Surgical Endoscopy and Other Interventional Techniques | 1994 | 134 |
| 26 | Somatic EGFR Mutation and Gene Copy Gain as Predictive Biomarkers for Response to Tyrosine Kinase Inhibitors in Non–Small Cell Lung Cancer | Clinical Cancer Research | 2010 | 134 |
| 27 | Use of Mycobacterial Smears in the Diagnosis of Pulmonary Tuberculosis in AIDS/ARC Patients | Chest | 1989 | 125 |
| 28 | Nurses’ knowledge, attitudes, and practices regarding provision of sexual health care in patients with cancer: critical review of the evidence | Supportive Care in Cancer | 2009 | 124 |
| 29 | Impact of improved survival of very low birth weight infants on recent secular trends in the prevalence of cerebral palsy | Pediatrics | 1993 | 123 |
| 30 | Laryngeal View During Laryngoscopy: A Randomized Trial Comparing Cricoid Pressure, Backward-Upward-Rightward Pressure, and Bimanual Laryngoscopy | Annals of Emergency Medicine | 2006 | 122 |
| 31 | Use of the Laryngeal Mask Airway as an Alternative to the Tracheal Tube During Ambulatory Anesthesia | Anesthesia and Analgesia | 1997 | 121 |
| 32 | Drug-induced photoallergic and phototoxic reactions | Expert Opinion on Drug Safety | 2007 | 121 |
| 33 | Temozolomide (TMZ) combined with cisplatin (CDDP) in patients with brain metastases from solid tumors: a Hellenic Cooperative Oncology Group (HeCOG) Phase II study | Journal of Neuro-Oncology | 2005 | 118 |
| 34 | Calcium supplementation in premenstrual syndrome | Journal of General Internal Medicine | 1989 | 117 |
| 35 | Hormone Replacement Therapy in Women with Epilepsy: A Randomized, Double-Blind, Placebo-Controlled Study | Epilepsia | 2006 | 116 |
| 36 | Central nervous system involvement in patients with acquired immune deficiency syndrome (AIDS) | Acta Neurologica Scandinavica | 1985 | 113 |
| 37 | Borate transporter SLC4A11 mutations cause both Harboyan syndrome and non-syndromic corneal endothelial dystrophy | Journal of Medical Genetics | 2007 | 111 |
| 38 | The Pterygopalatine Ganglion and its Role in Various Pain Syndromes: From Anatomy to Clinical Practice | Pain Practice | 2012 | 110 |
| 39 | Gemcitabine and carboplatin combination as first-line treatment in elderly patients and those unfit for cisplatin-based chemotherapy with advanced bladder carcinoma: Phase II study of the Hellenic Co-operative Oncology Group | Urology | 2004 | 108 |
| 40 | Pancreas in primary malnutrition disorders | American Journal of Clinical Nutrition | 1973 | 107 |
| 41 | Barriers to adherence to asthma management guidelines among inner-city primary care providers | Annals of Allergy, Asthma and Immunology | 2008 | 107 |
| 42 | The effect of maternal viral load on the risk of perinatal transmission of HIV-1 | Aids | 1997 | 106 |
| 43 | Global impact of COVID-19 on stroke care | International Journal of Stroke | 2021 | 104 |
| 44 | Prevalence and change in psychiatric disorders among perinatally HIV-infected and HIV-exposed youth | AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV | 2012 | 103 |
| 45 | Age-Related Decrement in Hearing for Speech: Sampling and Longitudinal Studies | Journal of Gerontology | 1976 | 102 |
| 46 | Trimethoprim-sulfamethoxazole versus pentamidine for Pneumocystis carinii pneumonia in AIDS patients | Aids | 1992 | 102 |
| 47 | An international study on the use of peroral endoscopic myotomy in the management of Zenker’s diverticulum | Gastrointestinal Endoscopy | 2020 | 102 |
| 48 | Amniocentesis for selection before rescue cerclage | Obstetrics and Gynecology | 2000 | 96 |
| 49 | Intensive medical management of ureteral calculi | Urology | 2000 | 96 |
| 50 | Central nervous system infarction related to cocaine abuse. | Stroke | 1991 | 95 |
