| # | Title | Journal | Year | Citations |
|---|
| 1 | Colorectal cancer statistics, 2020 | Ca-A Cancer Journal for Clinicians | 2020 | 3,302 |
| 2 | Surgeon Volume and Operative Mortality in the United States | New England Journal of Medicine | 2003 | 2,911 |
| 3 | Clinical Guidelines for the Use of Chronic Opioid Therapy in Chronic Noncancer Pain | Journal of Pain | 2009 | 1,960 |
| 4 | Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation | Genome Biology | 2004 | 1,396 |
| 5 | A Randomized Trial of Aspirin to Prevent Colorectal Adenomas | New England Journal of Medicine | 2003 | 1,358 |
| 6 | Guidelines on the Use of Therapeutic Apheresis in Clinical Practice – Evidence‐Based Approach from the Writing Committee of the American Society for Apheresis: The Eighth Special Issue | Journal of Clinical Apheresis | 2019 | 1,263 |
| 7 | Combining independent studies of a diagnostic test into a summary roc curve: Data-analytic approaches and some additional considerations | Statistics in Medicine | 1993 | 1,238 |
| 8 | Pulmonary Rehabilitation | Chest | 2007 | 1,145 |
| 9 | Matrix Metalloproteinases: Role In Arthritis | Frontiers in Bioscience - Landmark | 2006 | 1,086 |
| 10 | ACG Clinical Guideline: Ulcerative Colitis in Adults | American Journal of Gastroenterology | 2019 | 933 |
| 11 | Characteristics of medial temporal lobe epilepsy: I. Results of history and physical examination | Annals of Neurology | 1993 | 844 |
| 12 | Calcium Supplements for the Prevention of Colorectal Adenomas | New England Journal of Medicine | 1999 | 830 |
| 13 | Inhibition of Microglial Activation Attenuates the Development but Not Existing Hypersensitivity in a Rat Model of Neuropathy | Journal of Pharmacology and Experimental Therapeutics | 2003 | 733 |
| 14 | Wide Variation and Excessive Dosage of Opioid Prescriptions for Common General Surgical Procedures | Annals of Surgery | 2017 | 729 |
| 15 | Controversies in RBC Transfusion in the Critically Ill | Chest | 2007 | 685 |
| 16 | Sarcopenic obesity in older adults: aetiology, epidemiology and treatment strategies | Nature Reviews Endocrinology | 2018 | 676 |
| 17 | Incomplete Polyp Resection During Colonoscopy—Results of the Complete Adenoma Resection (CARE) Study | Gastroenterology | 2013 | 663 |
| 18 | Histopathological features of diagnostic and clinical relevance in autoimmune pancreatitis: a study on 53 resection specimens and 9 biopsy specimens | Virchows Archiv Fur Pathologische Anatomie Und Physiologie Und Fur Klinische Medizin | 2004 | 630 |
| 19 | Pharmacological Treatment of Coronary Artery Disease With Recombinant Fibroblast Growth Factor-2 | Circulation | 2002 | 621 |
| 20 | National trends in lower extremity bypass surgery, endovascular interventions, and major amputations | Journal of Vascular Surgery | 2009 | 615 |
| 21 | A clinical prototype for active microwave imaging of the breast | IEEE Transactions on Microwave Theory and Techniques | 2000 | 607 |
| 22 | Prediction of rupture risk in abdominal aortic aneurysm during observation: Wall stress versus diameter | Journal of Vascular Surgery | 2003 | 607 |
| 23 | Classification of types of intraductal papillary-mucinous neoplasm of the pancreas: a consensus study | Virchows Archiv Fur Pathologische Anatomie Und Physiologie Und Fur Klinische Medizin | 2005 | 595 |
| 24 | American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis | Gastroenterology | 2018 | 591 |
| 25 | The antiestrogenic effect of cigarette smoking in women | American Journal of Obstetrics and Gynecology | 1990 | 557 |
| 26 | A recurrent 16p12.1 microdeletion supports a two-hit model for severe developmental delay | Nature Genetics | 2010 | 539 |
| 27 | Guidelines on the Use of Therapeutic Apheresis in Clinical Practice—Evidence‐Based Approach from the Writing Committee of the American Society for Apheresis: The Sixth Special Issue | Journal of Clinical Apheresis | 2013 | 520 |
| 28 | Two‐year seizure reduction in adults with medically intractable partial onset epilepsy treated with responsive neurostimulation: Final results of the RNS System Pivotal trial | Epilepsia | 2014 | 520 |
| 29 | Altered MicroRNA Expression Confined to Specific Epithelial Cell Subpopulations in Breast Cancer | Cancer Research | 2007 | 515 |
| 30 | Complete Freunds adjuvant-induced peripheral inflammation evokes glial activation and proinflammatory cytokine expression in the CNS | European Journal of Neuroscience | 2004 | 513 |
| 31 | A Pooled Analysis of Eastern Cooperative Oncology Group and Intergroup Trials of Adjuvant High-Dose Interferon for Melanoma | Clinical Cancer Research | 2004 | 510 |
| 32 | UPPER TRACT UROTHELIAL NEOPLASMS: INCIDENCE AND SURVIVAL DURING THE LAST 2 DECADES | Journal of Urology | 2000 | 500 |
| 33 | Intraoperative Brain Shift and Deformation: A Quantitative Analysis of Cortical Displacement in 28 Cases | Neurosurgery | 1998 | 493 |
| 34 | Resective Epilepsy Surgery for Drug-Resistant Focal Epilepsy | JAMA - Journal of the American Medical Association | 2015 | 488 |
| 35 | Humanization of Yeast to Produce Complex Terminally Sialylated Glycoproteins | Science | 2006 | 482 |
| 36 | Cost-Effectiveness of CT Screening in the National Lung Screening Trial | New England Journal of Medicine | 2014 | 471 |
| 37 | Characteristics of medial temporal lobe epilepsy: II. Interictal and ictal scalp electroencephalography, neuropsychological testing, neuroimaging, surgical results, and pathology | Annals of Neurology | 1993 | 462 |
| 38 | Risk of Lymphoma Associated With Combination Anti–Tumor Necrosis Factor and Immunomodulator Therapy for the Treatment of Crohn's Disease: A Meta-Analysis | Clinical Gastroenterology and Hepatology | 2009 | 459 |
| 39 | Differential Working Memory Load Effects after Mild Traumatic Brain Injury | NeuroImage | 2001 | 452 |
| 40 | Brain activation during working memory 1 month after mild traumatic brain injury | Neurology | 1999 | 444 |
| 41 | Guidelines on the use of therapeutic apheresis in clinical practice—Evidence‐based approach from the apheresis applications committee of the American Society for Apheresis | Journal of Clinical Apheresis | 2010 | 441 |
| 42 | In vivo analysis of mechanical wall stress and abdominal aortic aneurysm rupture risk | Journal of Vascular Surgery | 2002 | 437 |
| 43 | Evading apoptosis in cancer | Trends in Cell Biology | 2013 | 436 |
| 44 | Lactated Ringer's Solution Reduces Systemic Inflammation Compared With Saline in Patients With Acute Pancreatitis | Clinical Gastroenterology and Hepatology | 2011 | 432 |
| 45 | ACG and CAG Clinical Guideline: Management of Dyspepsia | American Journal of Gastroenterology | 2017 | 431 |
| 46 | Colorectal Cancer in Patients Under Close Colonoscopic Surveillance | Gastroenterology | 2005 | 421 |
| 47 | 临床实践中治疗性单采术应用指南——基于美国血浆置换学会编写委员会的循证策略：第七版 | Journal of Clinical Apheresis | 2016 | 421 |
| 48 | Optimization of humanized IgGs in glycoengineered Pichia pastoris | Nature Biotechnology | 2006 | 419 |
| 49 | National Performance Benchmarks for Modern Screening Digital Mammography: Update from the Breast Cancer Surveillance Consortium | Radiology | 2017 | 418 |
| 50 | Persistent colonisation of potable water as a source of Mycobacterium avium infection in AIDS | Lancet, The | 1994 | 416 |
