| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Tissue microarrays for high-throughput molecular profiling of tumor specimens | Nature Medicine | 1998 | 3,661 |
| 3 | Biological, clinical and population relevance of 95 loci for blood lipids | Nature | 2010 | 3,249 |
| 4 | Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index | Nature Genetics | 2010 | 2,634 |
| 5 | Premature ageing in mice expressing defective mitochondrial DNA polymerase | Nature | 2004 | 2,318 |
| 6 | Synaptic, transcriptional and chromatin genes disrupted in autism | Nature | 2014 | 2,254 |
| 7 | Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology | Epilepsia | 2017 | 2,191 |
| 8 | Hundreds of variants clustered in genomic loci and biological pathways affect human height | Nature | 2010 | 1,789 |
| 9 | Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease | Nature Genetics | 2011 | 1,685 |
| 10 | Large-scale association analysis identifies new risk loci for coronary artery disease | Nature Genetics | 2013 | 1,439 |
| 11 | In vivo amplification of the androgen receptor gene and progression of human prostate cancer | Nature Genetics | 1995 | 1,316 |
| 12 | Updated 2016 EAU Guidelines on Muscle-invasive and Metastatic Bladder Cancer | European Urology | 2017 | 1,241 |
| 13 | Optimizing comparative genomic hybridization for analysis of DNA sequence copy number changes in solid tumors | Genes Chromosomes and Cancer | 1994 | 1,215 |
| 14 | Genome-wide association study identifies 74 loci associated with educational attainment | Nature | 2016 | 1,204 |
| 15 | The evolutionary history of lethal metastatic prostate cancer | Nature | 2015 | 1,185 |
| 16 | European Association of Urology Guidelines on Muscle-invasive and Metastatic Bladder Cancer: Summary of the 2020 Guidelines | European Urology | 2021 | 1,152 |
| 17 | Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture | Nature Genetics | 2012 | 1,100 |
| 18 | HRS Expert Consensus Statement on the Diagnosis and Management of Arrhythmias Associated With Cardiac Sarcoidosis | Heart Rhythm | 2014 | 1,077 |
| 19 | Tumor infiltrating lymphocytes are prognostic in triple negative breast cancer and predictive for trastuzumab benefit in early breast cancer: results from the FinHER trial | Annals of Oncology | 2014 | 1,022 |
| 20 | A Review of Indocyanine Green Fluorescent Imaging in Surgery | International Journal of Biomedical Imaging | 2012 | 972 |
| 21 | Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits | Nature Genetics | 2018 | 924 |
| 22 | Muscle Injuries | American Journal of Sports Medicine | 2005 | 905 |
| 23 | Human Estrogen Receptor β-Gene Structure, Chromosomal Localization, and Expression Pattern1 | Journal of Clinical Endocrinology and Metabolism | 1997 | 879 |
| 24 | Multiple common variants for celiac disease influencing immune gene expression | Nature Genetics | 2010 | 871 |
| 25 | Spectrum of gluten-related disorders: consensus on new nomenclature and classification | BMC Medicine | 2012 | 855 |
| 26 | Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution | Nature Genetics | 2010 | 836 |
| 27 | MicroRNA Expression Profiling in Prostate Cancer | Cancer Research | 2007 | 833 |
| 28 | Probiotics in the management of atopic eczema | Clinical and Experimental Allergy | 2000 | 792 |
| 29 | Nitric Oxide Production and Signaling in Inflammation | Inflammation and Allergy: Drug Targets | 2005 | 770 |
| 30 | GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment | Science | 2013 | 750 |
| 31 | Comparison of combination therapy with single-drug therapy in early rheumatoid arthritis: a randomised trial | Lancet, The | 1999 | 725 |
| 32 | κB Activations, Whereas Flavone, Isorhamnetin, Naringenin, and Pelargonidin Inhibit only NF-κB Activation along with Their Inhibitory Effect on iNOS Expression and NO Production in Activated Macrophages">Anti-Inflammatory Effects of Flavonoids: Genistein, Kaempferol, Quercetin, and Daidzein Inhibit STAT-1 and NF-κB Activations, Whereas Flavone, Isorhamnetin, Naringenin, and Pelargonidin Inhibit only NF-κB Activation along with Their Inhibitory Effect on iNOS Expression and NO Production in Activated Macrophages | Mediators of Inflammation | 2007 | 712 |
| 33 | Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes | American Journal of Human Genetics | 2019 | 711 |
| 34 | Toward defining the autoimmune microbiome for type 1 diabetes | ISME Journal | 2011 | 709 |
| 35 | Overdiagnosis and Overtreatment of Prostate Cancer | European Urology | 2014 | 709 |
| 36 | Instruction manual for the ILAE 2017 operational classification of seizure types | Epilepsia | 2017 | 699 |
| 37 | Genome-wide association analyses identify 18 new loci associated with serum urate concentrations | Nature Genetics | 2013 | 675 |
| 38 | Increasing prevalence of coeliac disease over time | Alimentary Pharmacology and Therapeutics | 2007 | 662 |
| 39 | Gut Microbiome Metagenomics Analysis Suggests a Functional Model for the Development of Autoimmunity for Type 1 Diabetes | PLoS ONE | 2011 | 660 |
| 40 | The prevalence of celiac disease in Europe: Results of a centralized, international mass screening project | Annals of Medicine | 2010 | 658 |
| 41 | Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci | Nature Genetics | 2018 | 652 |
| 42 | Enhancement of the Circulating Antibody Secreting Cell Response in Human Diarrhea by a Human Lactobacillus Strain | Pediatric Research | 1992 | 646 |
| 43 | Evidence for a prostate cancer susceptibility locus on the X chromosome. | Nature Genetics | 1998 | 641 |
| 44 | Pupil size variation as an indication of affective processing | International Journal of Human Computer Studies | 2003 | 634 |
| 45 | Changes in circulating microRNA levels associated with prostate cancer | British Journal of Cancer | 2012 | 633 |
| 46 | Epidemiology of hip fractures | Bone | 1996 | 622 |
| 47 | Percutaneous coronary angioplasty versus coronary artery bypass grafting in treatment of unprotected left main stenosis (NOBLE): a prospective, randomised, open-label, non-inferiority trial | Lancet, The | 2016 | 620 |
| 48 | Long Noncoding RNA in Prostate, Bladder, and Kidney Cancer | European Urology | 2014 | 601 |
| 49 | European Society Paediatric Gastroenterology, Hepatology and Nutrition Guidelines for Diagnosing Coeliac Disease 2020 | Journal of Pediatric Gastroenterology and Nutrition | 2020 | 601 |
| 50 | Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer | Nature Medicine | 2009 | 596 |
