| # | Title | Journal | Year | Citations |
|---|
| 1 | A Randomized Trial Comparing Postoperative Adjuvant Chemotherapy with Cisplatin and 5-Fluorouracil Versus Preoperative Chemotherapy for Localized Advanced Squamous Cell Carcinoma of the Thoracic Esophagus (JCOG9907) | Annals of Surgical Oncology | 2012 | 1,152 |
| 2 | Renal L-Type Fatty Acid–Binding Protein in Acute Ischemic Injury | Journal of the American Society of Nephrology: JASN | 2007 | 313 |
| 3 | Deletions and epimutations affecting the human 14q32.2 imprinted region in individuals with paternal and maternal upd(14)-like phenotypes | Nature Genetics | 2008 | 266 |
| 4 | MLL2 and KDM6A mutations in patients with Kabuki syndrome | American Journal of Medical Genetics, Part A | 2013 | 148 |
| 5 | Prevalence of dry eye in Japanese eye centers | Graefe's Archive for Clinical and Experimental Ophthalmology | 1995 | 142 |
| 6 | Guidelines for the Intravenous Application of Recombinant Tissue-type Plasminogen Activator (Alteplase), the Second Edition, October 2012: A Guideline From the Japan Stroke Society | Journal of Stroke and Cerebrovascular Diseases | 2013 | 126 |
| 7 | Prospective and retrospective studies of recovery in aphasia. Changes in cerebral blood flow and language functions | Brain | 1998 | 122 |
| 8 | Randomized study of low‐dose versus standard‐dose chemoradiotherapy for unresectable esophageal squamous cell carcinoma (JCOG0303) | Cancer Science | 2015 | 116 |
| 9 | Characteristics of Early-Onset vs Late-Onset Colorectal Cancer | JAMA Surgery | 2021 | 110 |
| 10 | Functional Corneal Endothelium Derived from Corneal Stroma Stem Cells of Neural Crest Origin by Retinoic Acid and Wnt/β-Catenin Signaling | Stem Cells and Development | 2013 | 106 |
| 11 | Tear function and ocular surface changes in keratoconus | Ophthalmology | 2003 | 104 |
| 12 | Incidence and Risk Factors of Postoperative Delirium in Patients with Esophageal Cancer | Annals of Surgical Oncology | 2012 | 92 |
| 13 | Identification of novel direct transcriptional targets of glucocorticoid receptor | Leukemia | 2004 | 86 |
| 14 | Evaluation of factors associated with the anxiety and depression of female infertility patients | BioPsychoSocial Medicine | 2011 | 83 |
| 15 | The W258X mutation in SLC22A12 is the predominant cause of Japanese renal hypouricemia | Pediatric Nephrology | 2004 | 79 |
| 16 | Alterations of the ocular surface epithelial MUC16 and goblet cell MUC5AC in patients with atopic keratoconjunctivitis | Allergy: European Journal of Allergy and Clinical Immunology | 2008 | 76 |
| 17 | New Techniques for Exposure of Posterior Cervical Spine Through Intermuscular Planes and Their Surgical Application | Spine | 2012 | 73 |
| 18 | Ocular Surface and MUC5AC Alterations in Atopic Patients with Corneal Shield Ulcers | Current Eye Research | 2005 | 69 |
| 19 | Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2020 for the Clinical Practice of Hereditary Colorectal Cancer | International Journal of Clinical Oncology | 2021 | 67 |
| 20 | Evolution of Computed Tomographic Characteristics of Spontaneous Isolated Superior Mesenteric Artery Dissection During Conservative Management | Circulation Journal | 2016 | 66 |
| 21 | Japanese Guidelines for the Management of Respiratory Infectious Diseases in Children 2007 with focus on pneumonia | Pediatrics International | 2011 | 63 |
| 22 | Effects of Diquafosol Sodium Eye Drops on Tear Film Stability in Short BUT Type of Dry Eye | Cornea | 2013 | 62 |
| 23 | Association between COVID-19 vaccine hesitancy and generalized trust, depression, generalized anxiety, and fear of COVID-19 | BMC Public Health | 2022 | 60 |
| 24 | Japanese Guideline for Allergic Conjunctival Diseases | Allergology International | 2011 | 59 |
| 25 | Role of Nampt-Sirt6 Axis in Renal Proximal Tubules in Extracellular Matrix Deposition in Diabetic Nephropathy | Cell Reports | 2019 | 59 |
| 26 | Molecular pathology of Shprintzen-Goldberg syndrome | American Journal of Medical Genetics, Part A | 2006 | 57 |
| 27 | Efficacy and Safety of Long-term Corticosteroid Eye Drops after Penetrating Keratoplasty | Ophthalmology | 2012 | 57 |
| 28 | Atopic Ocular Surface Disease | Cornea | 2005 | 56 |
| 29 | Wisconsin card sorting test in children with temporal lobe epilepsy | Brain and Development | 2002 | 55 |
| 30 | SUPPRESSIVE EFFECTS OF DIESEL EXHAUST PARTICLES ON CYTOKINE RELEASE FROM HUMAN AND MURINE ALVEOLAR MACROPHAGES | Experimental Lung Research | 2003 | 55 |
| 31 | Experimental scoliosis in melatonin-deficient C57BL/6J mice without pinealectomy | Journal of Pineal Research | 2006 | 55 |
| 32 | Regulatory mechanisms for the production of BAFF and IL-6 are impaired in monocytes of patients of primary Sjögren's syndrome | Arthritis Research and Therapy | 2011 | 54 |
| 33 | Repetitive Monomorphic Ventricular Tachycardia of Left Coronary Cusp Origin | PACE - Pacing and Clinical Electrophysiology | 1999 | 52 |
| 34 | Next‐generation sequencing for patients with non‐obstructive azoospermia: implications for significant roles of monogenic/oligogenic mutations | Andrology | 2017 | 51 |
| 35 | Utilizing a low-cost desktop 3D printer to develop a “one-stop 3D printing lab” for oral and maxillofacial surgery and dentistry fields | 3D Printing in Medicine | 2018 | 51 |
| 36 | Clinical features and varieties of non-motor fluctuations in Parkinson's disease: A Japanese multicenter study | Parkinsonism and Related Disorders | 2013 | 50 |
| 37 | Alterations of the ocular surface epithelial mucins 1, 2, 4 and the tear functions in patients with atopic keratoconjunctivitis | Clinical and Experimental Allergy | 2006 | 49 |
| 38 | Metastatic Patterns of Myxoid/Round Cell Liposarcoma: A Review of a 25-Year Experience | Sarcoma | 2012 | 48 |
| 39 | Appropriateness Ratings of Percutaneous Coronary Intervention in Japan and Its Association With the Trend of Noninvasive Testing | JACC: Cardiovascular Interventions | 2014 | 48 |
| 40 | Risk factors for olfactory dysfunction in chronic rhinosinusitis | Auris Nasus Larynx | 2013 | 46 |
| 41 | A case of allergic bronchopulmonary aspergillosis successfully treated with mepolizumab | BMC Pulmonary Medicine | 2018 | 46 |
| 42 | Gene expression of interstitial collagenase (matrix metalloproteinase 1) in gastrointestinal tract cancers | Journal of Gastroenterology | 1994 | 45 |
| 43 | A Simple Method to Induce Differentiation of Murine Bone Marrow Mesenchymal Cells to Insulin-producing Cells Using Conophylline and Betacellulin-delta4 | Endocrine Journal | 2008 | 44 |
| 44 | Detection of HEY1‐NCOA2 fusion by fluorescence in‐situ hybridization in formalin‐fixed paraffin‐embedded tissues as a possible diagnostic tool for mesenchymal chondrosarcoma | Pathology International | 2012 | 44 |
| 45 | Corneal Endothelial Regeneration Using Mesenchymal Stem Cells Derived from Human Umbilical Cord | Stem Cells and Development | 2018 | 44 |
| 46 | Early visual results with the 1CU accommodating intraocular lens | Journal of Cataract and Refractive Surgery | 2005 | 42 |
| 47 | Retrospective analysis of the clinical response of palmoplantar pustulosis after dental infection control and dental metal removal | Journal of Dermatology | 2017 | 42 |
| 48 | Muscle-Preserving Selective Laminectomy Maintained the Compensatory Mechanism of Cervical Lordosis After Surgery | Spine | 2018 | 42 |
| 49 | Cervical laminectomy of limited width prevents postoperative C5 palsy: a multivariate analysis of 263 muscle-preserving posterior decompression cases | European Spine Journal | 2017 | 41 |
| 50 | CT Imaging Features of Antiresorptive agent-Related Osteonecrosis of the Jaw/ Medication-Related Osteonecrosis of the Jaws | Dentomaxillofacial Radiology | 2018 | 41 |
