| # | Title | Journal | Year | Citations |
|---|
| 1 | Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study | Lancet Oncology, The | 2011 | 3,758 |
| 2 | Afatinib versus cisplatin plus gemcitabine for first-line treatment of Asian patients with advanced non-small-cell lung cancer harbouring EGFR mutations (LUX-Lung 6): an open-label, randomised phase 3 trial | Lancet Oncology, The | 2014 | 1,740 |
| 3 | Maintenance pemetrexed plus best supportive care versus placebo plus best supportive care for non-small-cell lung cancer: a randomised, double-blind, phase 3 study | Lancet, The | 2009 | 1,062 |
| 4 | Preexistence and Clonal Selection of MET Amplification in EGFR Mutant NSCLC | Cancer Cell | 2010 | 956 |
| 5 | First-line ceritinib versus platinum-based chemotherapy in advanced ALK -rearranged non-small-cell lung cancer (ASCEND-4): a randomised, open-label, phase 3 study | Lancet, The | 2017 | 919 |
| 6 | Regorafenib plus best supportive care versus placebo plus best supportive care in Asian patients with previously treated metastatic colorectal cancer (CONCUR): a randomised, double-blind, placebo-controlled, phase 3 trial | Lancet Oncology, The | 2015 | 574 |
| 7 | Mutation incidence and coincidence in non small-cell lung cancer: meta-analyses by ethnicity and histology (mutMap) | Annals of Oncology | 2013 | 510 |
| 8 | COVID-19 in patients with thoracic malignancies (TERAVOLT): first results of an international, registry-based, cohort study | Lancet Oncology, The | 2020 | 503 |
| 9 | Concurrent chemoradiotherapy plus adjuvant chemotherapy versus concurrent chemoradiotherapy alone in patients with locoregionally advanced nasopharyngeal carcinoma: a phase 3 multicentre randomised controlled trial | Lancet Oncology, The | 2012 | 468 |
| 10 | Gefitinib versus vinorelbine plus cisplatin as adjuvant treatment for stage II–IIIA (N1–N2) EGFR-mutant NSCLC (ADJUVANT/CTONG1104): a randomised, open-label, phase 3 study | Lancet Oncology, The | 2018 | 436 |
| 11 | Guidelines for the Diagnosis and Treatment of Hepatocellular Carcinoma (2019 Edition) | Liver Cancer | 2020 | 427 |
| 12 | Guidelines for Diagnosis and Treatment of Primary Liver Cancer in China (2017 Edition) | Liver Cancer | 2018 | 426 |
| 13 | Challenges to effective cancer control in China, India, and Russia | Lancet Oncology, The | 2014 | 411 |
| 14 | Final overall survival results from a randomised, phase III study of erlotinib versus chemotherapy as first-line treatment of EGFR mutation-positive advanced non-small-cell lung cancer (OPTIMAL, CTONG-0802) | Annals of Oncology | 2015 | 406 |
| 15 | Diagnostic Accuracy of Fast Computational Approaches to Derive Fractional Flow Reserve From Diagnostic Coronary Angiography | JACC: Cardiovascular Interventions | 2016 | 394 |
| 16 | Curcumin, Inflammation, and Chronic Diseases: How Are They Linked? | Molecules | 2015 | 391 |
| 17 | Icotinib versus gefitinib in previously treated advanced non-small-cell lung cancer (ICOGEN): a randomised, double-blind phase 3 non-inferiority trial | Lancet Oncology, The | 2013 | 389 |
| 18 | CNS Efficacy of Osimertinib in Patients With T790M-Positive Advanced Non–Small-Cell Lung Cancer: Data From a Randomized Phase III Trial (AURA3) | Journal of Clinical Oncology | 2018 | 359 |
| 19 | Diagnostic Accuracy of Angiography-Based Quantitative Flow Ratio Measurements for Online Assessment of Coronary Stenosis | Journal of the American College of Cardiology | 2017 | 355 |
| 20 | Central focused convolutional neural networks: Developing a data-driven model for lung nodule segmentation | Medical Image Analysis | 2017 | 352 |
| 21 | Modified FOLFOX6 With or Without Radiation Versus Fluorouracil and Leucovorin With Radiation in Neoadjuvant Treatment of Locally Advanced Rectal Cancer: Initial Results of the Chinese FOWARC Multicenter, Open-Label, Randomized Three-Arm Phase III Trial | Journal of Clinical Oncology | 2016 | 307 |
| 22 | A translational study of circulating cell-free microRNA-1 in acute myocardial infarction | Clinical Science | 2010 | 298 |
| 23 | Ischaemic preconditioning-regulated miR-21 protects heart against ischaemia/reperfusion injury via anti-apoptosis through its target PDCD4 | Cardiovascular Research | 2010 | 296 |
| 24 | Fractional Flow Reserve Calculation From 3-Dimensional Quantitative Coronary Angiography and TIMI Frame Count | JACC: Cardiovascular Interventions | 2014 | 292 |
| 25 | Intercalated combination of chemotherapy and erlotinib for patients with advanced stage non-small-cell lung cancer (FASTACT-2): a randomised, double-blind trial | Lancet Oncology, The | 2013 | 280 |
| 26 | Circulating miR‐221 directly amplified from plasma is a potential diagnostic and prognostic marker of colorectal cancer and is correlated with p53 expression | Journal of Gastroenterology and Hepatology (Australia) | 2010 | 267 |
| 27 | Nivolumab Versus Docetaxel in a Predominantly Chinese Patient Population With Previously Treated Advanced NSCLC: CheckMate 078 Randomized Phase III Clinical Trial | Journal of Thoracic Oncology | 2019 | 260 |
| 28 | Bivalirudin vs Heparin With or Without Tirofiban During Primary Percutaneous Coronary Intervention in Acute Myocardial Infarction | JAMA - Journal of the American Medical Association | 2015 | 256 |
| 29 | The prevalence of insomnia in the general population in China: A meta-analysis | PLoS ONE | 2017 | 247 |
| 30 | Effect of lifestyle intervention in patients with type 2 diabetes: A meta-analysis | Metabolism: Clinical and Experimental | 2015 | 234 |
| 31 | Bioresorbable Vascular Scaffolds Versus Metallic Stents in Patients With Coronary Artery Disease | Journal of the American College of Cardiology | 2015 | 228 |
| 32 | Neoadjuvant chemotherapy followed by concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in locoregionally advanced nasopharyngeal carcinoma: A phase III multicentre randomised controlled trial | European Journal of Cancer | 2017 | 226 |
| 33 | Oncogenic activation of the STAT3 pathway drives PD-L1 expression in natural killer/T-cell lymphoma | Blood | 2018 | 218 |
| 34 | Mesenchymal stem cell as salvage treatment for refractory chronic GVHD | Bone Marrow Transplantation | 2010 | 217 |
| 35 | Pan-Asian adapted Clinical Practice Guidelines for the management of patients with metastatic non-small-cell lung cancer: a CSCO–ESMO initiative endorsed by JSMO, KSMO, MOS, SSO and TOS | Annals of Oncology | 2019 | 214 |
| 36 | Radiomic machine-learning classifiers for prognostic biomarkers of advanced nasopharyngeal carcinoma | Cancer Letters | 2017 | 211 |
| 37 | Epidemiology and Clinical Correlates of AKI in Chinese Hospitalized Adults | Clinical Journal of the American Society of Nephrology: CJASN | 2015 | 210 |
| 38 | Leptomeningeal Metastases in Patients with NSCLC with EGFR Mutations | Journal of Thoracic Oncology | 2016 | 208 |
| 39 | Selective autophagy of intracellular organelles: Recent research advances | Theranostics | 2021 | 207 |
| 40 | A Prospective International Multicenter Study of AKI in the Intensive Care Unit | Clinical Journal of the American Society of Nephrology: CJASN | 2015 | 206 |
| 41 | Total Anomalous Pulmonary Venous Connection | Circulation | 2017 | 204 |
| 42 | Effect of Fruquintinib vs Placebo on Overall Survival in Patients With Previously Treated Metastatic Colorectal Cancer | JAMA - Journal of the American Medical Association | 2018 | 202 |
| 43 | PI3K/Akt and HIF‑1 signaling pathway in hypoxia‑ischemia (Review) | Molecular Medicine Reports | 2018 | 201 |
| 44 | Effects of contrast-enhancement, reconstruction slice thickness and convolution kernel on the diagnostic performance of radiomics signature in solitary pulmonary nodule | Scientific Reports | 2016 | 197 |
| 45 | Unique genetic profiles from cerebrospinal fluid cell-free DNA in leptomeningeal metastases of EGFR-mutant non-small-cell lung cancer: a new medium of liquid biopsy | Annals of Oncology | 2018 | 197 |
| 46 | LncRNA TUG1 sponges miR-204-5p to promote osteoblast differentiation through upregulating Runx2 in aortic valve calcification | Cardiovascular Research | 2018 | 194 |
| 47 | CircRNA hsa_circRNA_104348 promotes hepatocellular carcinoma progression through modulating miR-187-3p/RTKN2 axis and activating Wnt/β-catenin pathway | Cell Death and Disease | 2020 | 194 |
| 48 | Preoperative prediction of sentinel lymph node metastasis in breast cancer based on radiomics of T2-weighted fat-suppression and diffusion-weighted MRI | European Radiology | 2018 | 193 |
| 49 | Alectinib versus crizotinib in untreated Asian patients with anaplastic lymphoma kinase-positive non-small-cell lung cancer (ALESIA): a randomised phase 3 study | Lancet Respiratory Medicine,the | 2019 | 192 |
| 50 | A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23 | Nature Genetics | 2013 | 188 |
