| # | Title | Journal | Year | Citations |
|---|
| 1 | The Human Brainnetome Atlas: A New Brain Atlas Based on Connectional Architecture | Cerebral Cortex | 2016 | 1,962 |
| 2 | A molecular atlas of cell types and zonation in the brain vasculature | Nature | 2018 | 1,310 |
| 3 | Prevalence of diabetes recorded in mainland China using 2018 diagnostic criteria from the American Diabetes Association: national cross sectional study | BMJ, The | 2020 | 809 |
| 4 | Macrophage Polarization in Inflammatory Diseases | International Journal of Biological Sciences | 2014 | 754 |
| 5 | Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT): a randomised pilot trial | Lancet Neurology, The | 2008 | 732 |
| 6 | ROS and Autophagy: Interactions and Molecular Regulatory Mechanisms | Cellular and Molecular Neurobiology | 2015 | 603 |
| 7 | Global brain inflammation in stroke | Lancet Neurology, The | 2019 | 469 |
| 8 | A novel gene, optrA, that confers transferable resistance to oxazolidinones and phenicols and its presence in Enterococcus faecalis and Enterococcus faecium of human and animal origin | Journal of Antimicrobial Chemotherapy | 2015 | 450 |
| 9 | CGCG clinical practice guidelines for the management of adult diffuse gliomas | Cancer Letters | 2016 | 448 |
| 10 | Crosstalk of autophagy and apoptosis: Involvement of the dual role of autophagy under ER stress | Journal of Cellular Physiology | 2017 | 405 |
| 11 | Blood Exosomes Endowed with Magnetic and Targeting Properties for Cancer Therapy | ACS Nano | 2016 | 362 |
| 12 | MicroRNA-221 and microRNA-222 regulate gastric carcinoma cell proliferation and radioresistance by targeting PTEN | BMC Cancer | 2010 | 339 |
| 13 | CXCL12/CXCR4: a symbiotic bridge linking cancer cells and their stromal neighbors in oncogenic communication networks | Oncogene | 2016 | 339 |
| 14 | Subregions of the human superior frontal gyrus and their connections | NeuroImage | 2013 | 333 |
| 15 | Organ-specific features of natural killer cells | Nature Reviews Immunology | 2011 | 332 |
| 16 | Increased miR‐124‐3p in microglial exosomes following traumatic brain injury inhibits neuronal inflammation and contributes to neurite outgrowthviatheir transfer into neurons | FASEB Journal | 2018 | 328 |
| 17 | RNA-seq of 272 gliomas revealed a novel, recurrent PTPRZ1-MET fusion transcript in secondary glioblastomas | Genome Research | 2014 | 316 |
| 18 | Single-cell analysis uncovers fibroblast heterogeneity and criteria for fibroblast and mural cell identification and discrimination | Nature Communications | 2020 | 316 |
| 19 | Single-cell RNA sequencing of mouse brain and lung vascular and vessel-associated cell types | Scientific Data | 2018 | 316 |
| 20 | Prevalence of polycystic ovary syndrome in women in China: a large community-based study | Human Reproduction | 2013 | 311 |
| 21 | Immune interventions in stroke | Nature Reviews Neurology | 2015 | 296 |
| 22 | Microenvironment Imbalance of Spinal Cord Injury | Cell Transplantation | 2018 | 281 |
| 23 | Dynamic functional network connectivity in idiopathic generalized epilepsy with generalized tonic-clonic seizure | Human Brain Mapping | 2017 | 275 |
| 24 | Resistance trends among clinical isolates in China reported from CHINET surveillance of bacterial resistance, 2005–2014 | Clinical Microbiology and Infection | 2016 | 274 |
| 25 | MiR-221 and miR-222 target PUMA to induce cell survival in glioblastoma | Molecular Cancer | 2010 | 269 |
| 26 | Progression of Myopia in School-Aged Children After COVID-19 Home Confinement | JAMA Ophthalmology | 2021 | 268 |
| 27 | Depletion of microglia exacerbates postischemic inflammation and brain injury | Journal of Cerebral Blood Flow and Metabolism | 2017 | 265 |
| 28 | Crosstalk of ER stress‐mediated autophagy and ER‐phagy: Involvement of UPR and the core autophagy machinery | Journal of Cellular Physiology | 2018 | 251 |
| 29 | Tumor cell-derived lactate induces TAZ-dependent upregulation of PD-L1 through GPR81 in human lung cancer cells | Oncogene | 2017 | 249 |
| 30 | Review of aerobic glycolysis and its key enzymes – new targets for lung cancer therapy | Thoracic Cancer | 2015 | 242 |
| 31 | The role of STAT3 in leading the crosstalk between human cancers and the immune system | Cancer Letters | 2018 | 237 |
| 32 | Efficacy and Safety of Low Dose Recombinant Tissue-Type Plasminogen Activator for the Treatment of Acute Pulmonary Thromboembolism | Chest | 2010 | 233 |
| 33 | Impact of an immune modulator fingolimod on acute ischemic stroke | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 229 |
| 34 | Combination of the Immune Modulator Fingolimod With Alteplase in Acute Ischemic Stroke | Circulation | 2015 | 229 |
| 35 | A review of the relationship between the gut microbiota and amino acid metabolism | Amino Acids | 2017 | 227 |
| 36 | Fingolimod for the Treatment of Intracerebral Hemorrhage | JAMA Neurology | 2014 | 224 |
| 37 | Ischemic neurons recruit natural killer cells that accelerate brain infarction | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 216 |
| 38 | Challenges and potential of PD-1/PD-L1 checkpoint blockade immunotherapy for glioblastoma | Journal of Experimental and Clinical Cancer Research | 2019 | 213 |
| 39 | Downregulation of Wnt2 and β-catenin by siRNA suppresses malignant glioma cell growth | Cancer Gene Therapy | 2009 | 209 |
| 40 | m6A RNA methylation regulators contribute to malignant progression and have clinical prognostic impact in gliomas | Aging | 2019 | 209 |
| 41 | Mobile Health Technology to Improve Care for Patients With Atrial Fibrillation | Journal of the American College of Cardiology | 2020 | 209 |
| 42 | Resting-state functional connectivity of the vermal and hemispheric subregions of the cerebellum with both the cerebral cortical networks and subcortical structures | NeuroImage | 2012 | 206 |
| 43 | Are isothiocyanates potential anti-cancer drugs? | Acta Pharmacologica Sinica | 2009 | 205 |
| 44 | Long non-coding RNAs: potential new biomarkers for predicting tumor invasion and metastasis | Molecular Cancer | 2016 | 200 |
| 45 | MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTEN-mutant) and LN229 (PTEN-wild type) to taxol | BMC Cancer | 2010 | 194 |
| 46 | Clinical practice guidelines for the management of adult diffuse gliomas | Cancer Letters | 2021 | 194 |
| 47 | Nanozyme-Based Bandage with Single-Atom Catalysis for Brain Trauma | ACS Nano | 2019 | 193 |
| 48 | Comparison of Tripterygium wilfordii Hook F with methotrexate in the treatment of active rheumatoid arthritis (TRIFRA): a randomised, controlled clinical trial | Annals of the Rheumatic Diseases | 2015 | 189 |
| 49 | A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23 | Nature Genetics | 2013 | 188 |
| 50 | Efficacy and Safety of Long-Term Universal Salt Iodization on Thyroid Disorders: Epidemiological Evidence from 31 Provinces of Mainland China | Thyroid | 2020 | 185 |
