| # | Title | Journal | Year | Citations |
|---|
| 1 | Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China | JAMA Internal Medicine | 2020 | 6,424 |
| 2 | Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial | Lancet Oncology, The | 2009 | 5,104 |
| 3 | Intravenous Fluids and Acute Kidney Injury | Blood Purification | 2017 | 4,905 |
| 4 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 5 | Randomized controlled trial of screening for hepatocellular carcinoma | Journal of Cancer Research and Clinical Oncology | 2004 | 1,185 |
| 6 | Cause-specific mortality for 240 causes in China during 1990–2013: a systematic subnational analysis for the Global Burden of Disease Study 2013 | Lancet, The | 2016 | 1,121 |
| 7 | Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody | Emerging Microbes and Infections | 2020 | 1,086 |
| 8 | Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults | Nature | 2018 | 1,074 |
| 9 | Systemic Immune-Inflammation Index Predicts Prognosis of Patients after Curative Resection for Hepatocellular Carcinoma | Clinical Cancer Research | 2014 | 1,012 |
| 10 | Prevalence and risk factors of chronic obstructive pulmonary disease in China (the China Pulmonary Health [CPH] study): a national cross-sectional study | Lancet, The | 2018 | 938 |
| 11 | p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload | Nature | 2007 | 809 |
| 12 | DNA Nanotechnology-Enabled Drug Delivery Systems | Chemical Reviews | 2019 | 768 |
| 13 | WFUMB Guidelines and Recommendations for Clinical Use of Ultrasound Elastography: Part 1: Basic Principles and Terminology | Ultrasound in Medicine and Biology | 2015 | 718 |
| 14 | COVID-19 with Different Severities: A Multicenter Study of Clinical Features | American Journal of Respiratory and Critical Care Medicine | 2020 | 690 |
| 15 | Persistence and clearance of viral RNA in 2019 novel coronavirus disease rehabilitation patients | Chinese Medical Journal | 2020 | 686 |
| 16 | Guidelines and Good Clinical Practice Recommendations for Contrast Enhanced Ultrasound (CEUS) in the Liver – Update 2012 | Ultrasound in Medicine and Biology | 2013 | 652 |
| 17 | Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci | Nature Genetics | 2018 | 652 |
| 18 | Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma | Cell | 2019 | 629 |
| 19 | WFUMB Guidelines and Recommendations for Clinical Use of Ultrasound Elastography: Part 3: Liver | Ultrasound in Medicine and Biology | 2015 | 620 |
| 20 | Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal | Molecular Cell | 2018 | 618 |
| 21 | Global, regional, and national levels of neonatal, infant, and under-5 mortality during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013 | Lancet, The | 2014 | 609 |
| 22 | PD-L1 Immunohistochemistry Comparability Study in Real-Life Clinical Samples: Results of Blueprint Phase 2 Project | Journal of Thoracic Oncology | 2018 | 589 |
| 23 | Tumor-Associated Neutrophils Recruit Macrophages and T-Regulatory Cells to Promote Progression of Hepatocellular Carcinoma and Resistance to Sorafenib | Gastroenterology | 2016 | 586 |
| 24 | Efficacy of Folic Acid Therapy in Primary Prevention of Stroke Among Adults With Hypertension in China | JAMA - Journal of the American Medical Association | 2015 | 577 |
| 25 | Frontline nurses’ burnout, anxiety, depression, and fear statuses and their associated factors during the COVID-19 outbreak in Wuhan, China: A large-scale cross-sectional study | EClinicalMedicine | 2020 | 566 |
| 26 | Plasma MicroRNA Panel to Diagnose Hepatitis B Virus–Related Hepatocellular Carcinoma | Journal of Clinical Oncology | 2011 | 554 |
| 27 | Oxidative stress in Alzheimer’s disease | Neuroscience Bulletin | 2014 | 547 |
| 28 | Association of Non-alcoholic Fatty Liver Disease with Chronic Kidney Disease: A Systematic Review and Meta-analysis | PLoS Medicine | 2014 | 507 |
| 29 | Decoding Alzheimer's disease from perturbed cerebral glucose metabolism: Implications for diagnostic and therapeutic strategies | Progress in Neurobiology | 2013 | 499 |
| 30 | Effect of Laparoscopic vs Open Distal Gastrectomy on 3-Year Disease-Free Survival in Patients With Locally Advanced Gastric Cancer | JAMA - Journal of the American Medical Association | 2019 | 477 |
| 31 | Guidelines and Good Clinical Practice Recommendations for Contrast Enhanced Ultrasound (CEUS) in the Liver – Update 2012 | Ultraschall in Der Medizin | 2013 | 470 |
| 32 | Sintilimab plus a bevacizumab biosimilar (IBI305) versus sorafenib in unresectable hepatocellular carcinoma (ORIENT-32): a randomised, open-label, phase 2–3 study | Lancet Oncology, The | 2021 | 459 |
| 33 | First Human Imaging Studies with the EXPLORER Total-Body PET Scanner* | Journal of Nuclear Medicine | 2019 | 453 |
| 34 | STAT3-mediated upregulation of lncRNA HOXD-AS1 as a ceRNA facilitates liver cancer metastasis by regulating SOX4 | Molecular Cancer | 2017 | 434 |
| 35 | Guidelines for the Diagnosis and Treatment of Hepatocellular Carcinoma (2019 Edition) | Liver Cancer | 2020 | 427 |
| 36 | Guidelines for Diagnosis and Treatment of Primary Liver Cancer in China (2017 Edition) | Liver Cancer | 2018 | 426 |
| 37 | A beginner's guide to permanent left bundle branch pacing | Heart Rhythm | 2019 | 419 |
| 38 | The Chinese Society of Clinical Oncology (CSCO): clinical guidelines for the diagnosis and treatment of gastric cancer | Cancer Communications | 2019 | 418 |
| 39 | D-dimer as a biomarker for disease severity and mortality in COVID-19 patients: a case control study | Journal of Intensive Care | 2020 | 418 |
| 40 | Metroticket 2.0 Model for Analysis of Competing Risks of Death After Liver Transplantation for Hepatocellular Carcinoma | Gastroenterology | 2018 | 417 |
| 41 | A decade?s studies on metastasis of hepatocellular carcinoma | Journal of Cancer Research and Clinical Oncology | 2004 | 406 |
| 42 | The Lysosomal v-ATPase-Ragulator Complex Is a Common Activator for AMPK and mTORC1, Acting as a Switch between Catabolism and Anabolism | Cell Metabolism | 2014 | 406 |
| 43 | Standards of medical care for type 2 diabetes in China 2019 | Diabetes/Metabolism Research and Reviews | 2019 | 404 |
| 44 | Th17 and natural Treg cell population dynamics in systemic lupus erythematosus | Arthritis and Rheumatism | 2009 | 403 |
| 45 | Mass spectrometry-based metabolomics: a guide for annotation, quantification and best reporting practices | Nature Methods | 2021 | 403 |
| 46 | Octapod iron oxide nanoparticles as high-performance T2 contrast agents for magnetic resonance imaging | Nature Communications | 2013 | 399 |
| 47 | Single-cell landscape of the ecosystem in early-relapse hepatocellular carcinoma | Cell | 2021 | 399 |
| 48 | Exosomes Secreted by Human-Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Repair Critical-Sized Bone Defects through Enhanced Angiogenesis and Osteogenesis in Osteoporotic Rats | International Journal of Biological Sciences | 2016 | 397 |
| 49 | Negative regulation of lncRNA GAS5 by miR-21 | Cell Death and Differentiation | 2013 | 387 |
| 50 | Paracrine Action Enhances the Effects of Autologous Mesenchymal Stem Cell Transplantation on Vascular Regeneration in Rat Model of Myocardial Infarction | Annals of Thoracic Surgery | 2005 | 378 |
