| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2 | Nature Medicine | 2007 | 1,070 |
| 3 | A Human Genome Diversity Cell Line Panel | Science | 2002 | 907 |
| 4 | CellMarker: a manually curated resource of cell markers in human and mouse | Nucleic Acids Research | 2019 | 856 |
| 5 | Randomized, Double-Blind, Placebo-Controlled Phase III Trial of Apatinib in Patients With Chemotherapy-Refractory Advanced or Metastatic Adenocarcinoma of the Stomach or Gastroesophageal Junction | Journal of Clinical Oncology | 2016 | 756 |
| 6 | In Vivo Diagnosis of Plaque Erosion and Calcified Nodule in Patients With Acute Coronary Syndrome by Intravascular Optical Coherence Tomography | Journal of the American College of Cardiology | 2013 | 648 |
| 7 | The Genetic Legacy of the Mongols | American Journal of Human Genetics | 2003 | 512 |
| 8 | Circulating microRNA-1 as a potential novel biomarker for acute myocardial infarction | Biochemical and Biophysical Research Communications | 2010 | 491 |
| 9 | CancerSEA: a cancer single-cell state atlas | Nucleic Acids Research | 2019 | 458 |
| 10 | Transmission dynamics of the COVID‐19 outbreak and effectiveness of government interventions: A data‐driven analysis | Journal of Medical Virology | 2020 | 449 |
| 11 | Discovering disease-genes by topological features in human protein–protein interaction network | Bioinformatics | 2006 | 422 |
| 12 | The muscle-specific microRNAs miR-1 and miR-133 produce opposing effects on apoptosis by targeting HSP60, HSP70 and caspase-9 in cardiomyocytes | Journal of Cell Science | 2007 | 420 |
| 13 | Everolimus for Previously Treated Advanced Gastric Cancer: Results of the Randomized, Double-Blind, Phase III GRANITE-1 Study | Journal of Clinical Oncology | 2013 | 411 |
| 14 | MicroRNA-328 Contributes to Adverse Electrical Remodeling in Atrial Fibrillation | Circulation | 2010 | 403 |
| 15 | Hydrogen sulfide (H 2 S) metabolism in mitochondria and its regulatory role in energy production | Proceedings of the National Academy of Sciences of the United States of America | 2012 | 397 |
| 16 | Porphyrin photosensitizers in photodynamic therapy and its applications | Oncotarget | 2017 | 381 |
| 17 | Nicotine promotes atherosclerosis via ROS-NLRP3-mediated endothelial cell pyroptosis | Cell Death and Disease | 2018 | 371 |
| 18 | TIP: A Web Server for Resolving Tumor Immunophenotype Profiling | Cancer Research | 2018 | 356 |
| 19 | Genetic relationship of populations in China | Proceedings of the National Academy of Sciences of the United States of America | 1998 | 341 |
| 20 | Lnc2Cancer: a manually curated database of experimentally supported lncRNAs associated with various human cancers | Nucleic Acids Research | 2016 | 340 |
| 21 | METTL3 and ALKBH5 oppositely regulate m6A modification of TFEB mRNA, which dictates the fate of hypoxia/reoxygenation-treated cardiomyocytes | Autophagy | 2019 | 337 |
| 22 | Locally Administered Adipose-Derived Stem Cells Accelerate Wound Healing through Differentiation and Vasculogenesis | Cell Transplantation | 2011 | 328 |
| 23 | Downregulation of miR-133 and miR-590 contributes to nicotine-induced atrial remodelling in canines | Cardiovascular Research | 2009 | 323 |
| 24 | Factors affecting catastrophic health expenditure and impoverishment from medical expenses in China: policy implications of universal health insurance | Bulletin of the World Health Organization | 2012 | 318 |
| 25 | Melatonin prevents endothelial cell pyroptosis via regulation of long noncoding RNA MEG3/miR‐223/NLRP3 axis | Journal of Pineal Research | 2018 | 313 |
| 26 | LncRNA2Target v2.0: a comprehensive database for target genes of lncRNAs in human and mouse | Nucleic Acids Research | 2019 | 311 |
| 27 | Mining TCGA database for genes of prognostic value in glioblastoma microenvironment | Aging | 2018 | 311 |
| 28 | Fabrication of 3D flower-like black N-TiO2-x@MoS2 for unprecedented-high visible-light-driven photocatalytic performance | Applied Catalysis B: Environmental | 2017 | 310 |
| 29 | Inferring novel lncRNA–disease associations based on a random walk model of a lncRNA functional similarity network | Molecular BioSystems | 2014 | 296 |
| 30 | Pan-cancer characterization of immune-related lncRNAs identifies potential oncogenic biomarkers | Nature Communications | 2020 | 293 |
| 31 | Molecular characterization and clinical relevance of m6A regulators across 33 cancer types | Molecular Cancer | 2019 | 286 |
| 32 | Long Intergenic Noncoding RNA HOTAIR Is Overexpressed and Regulates PTEN Methylation in Laryngeal Squamous Cell Carcinoma | American Journal of Pathology | 2013 | 285 |
| 33 | MicroRNA-101 Inhibited Postinfarct Cardiac Fibrosis and Improved Left Ventricular Compliance via the FBJ Osteosarcoma Oncogene/Transforming Growth Factor-β1 Pathway | Circulation | 2012 | 277 |
| 34 | A Multicenter, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study of the Effects of Qili Qiangxin Capsules in Patients With Chronic Heart Failure | Journal of the American College of Cardiology | 2013 | 267 |
| 35 | Metformin Inhibits the NLRP3 Inflammasome via AMPK/mTOR-dependent Effects in Diabetic Cardiomyopathy | International Journal of Biological Sciences | 2019 | 263 |
| 36 | LncRNA PTAR promotes EMT and invasion-metastasis in serous ovarian cancer by competitively binding miR-101-3p to regulate ZEB1 expression | Molecular Cancer | 2018 | 260 |
| 37 | Genome-wide association identifies a susceptibility locus for coronary artery disease in the Chinese Han population | Nature Genetics | 2011 | 256 |
| 38 | Body mass index and susceptibility to knee osteoarthritis: A systematic review and meta-analysis | Joint Bone Spine | 2012 | 248 |
| 39 | MicroRNA-30d regulates cardiomyocyte pyroptosis by directly targeting foxo3a in diabetic cardiomyopathy | Cell Death and Disease | 2014 | 246 |
| 40 | MiRNA–miRNA synergistic network: construction via co-regulating functional modules and disease miRNA topological features | Nucleic Acids Research | 2011 | 245 |
| 41 | DincRNA: a comprehensive web-based bioinformatics toolkit for exploring disease associations and ncRNA function | Bioinformatics | 2018 | 241 |
| 42 | Bacteriostatic Effect of Quercetin as an Antibiotic Alternative In Vivo and Its Antibacterial Mechanism In Vitro | Journal of Food Protection | 2018 | 237 |
| 43 | Walking the interactome to identify human miRNA-disease associations through the functional link between miRNA targets and disease genes | BMC Systems Biology | 2013 | 227 |
| 44 | Discovery and validation of immune-associated long non-coding RNA biomarkers associated with clinically molecular subtype and prognosis in diffuse large B cell lymphoma | Molecular Cancer | 2017 | 227 |
| 45 | iLoc-lncRNA: predict the subcellular location of lncRNAs by incorporating octamer composition into general PseKNC | Bioinformatics | 2018 | 227 |
| 46 | Mechanical properties, degradation performance and cytotoxicity of Mg–Zn–Ca biomedical alloys with different compositions | Materials Science and Engineering C | 2011 | 225 |
| 47 | Molecular Signatures of Major Depression | Current Biology | 2015 | 224 |
| 48 | Erlotinib versus vinorelbine plus cisplatin as adjuvant therapy in Chinese patients with stage IIIA EGFR mutation-positive non-small-cell lung cancer (EVAN): a randomised, open-label, phase 2 trial | Lancet Respiratory Medicine,the | 2018 | 224 |
| 49 | An Immune-Related Six-lncRNA Signature to Improve Prognosis Prediction of Glioblastoma Multiforme | Molecular Neurobiology | 2018 | 221 |
| 50 | Identification of lncRNA-associated competing triplets reveals global patterns and prognostic markers for cancer | Nucleic Acids Research | 2015 | 219 |
