| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 2 | Development and clinical application of a rapid IgM‐IgG combined antibody test for SARS‐CoV‐2 infection diagnosis | Journal of Medical Virology | 2020 | 1,357 |
| 3 | Clinical characteristics of 24 asymptomatic infections with COVID-19 screened among close contacts in Nanjing, China | Science China Life Sciences | 2020 | 1,090 |
| 4 | A SARS-CoV-2 surrogate virus neutralization test based on antibody-mediated blockage of ACE2–spike protein–protein interaction | Nature Biotechnology | 2020 | 1,042 |
| 5 | Prevalence of diabetes recorded in mainland China using 2018 diagnostic criteria from the American Diabetes Association: national cross sectional study | BMJ, The | 2020 | 809 |
| 6 | Therapeutic peptides: current applications and future directions | Signal Transduction and Targeted Therapy | 2022 | 454 |
| 7 | Cytokine storm intervention in the early stages of COVID-19 pneumonia | Cytokine and Growth Factor Reviews | 2020 | 384 |
| 8 | The power of genetic diversity in genome-wide association studies of lipids | Nature | 2021 | 353 |
| 9 | Succination inactivates gasdermin D and blocks pyroptosis | Science | 2020 | 341 |
| 10 | A long noncoding RNA contributes to neuropathic pain by silencing Kcna2 in primary afferent neurons | Nature Neuroscience | 2013 | 319 |
| 11 | Omicron variant showed lower neutralizing sensitivity than other SARS-CoV-2 variants to immune sera elicited by vaccines after boost | Emerging Microbes and Infections | 2022 | 303 |
| 12 | Activation of ferritinophagy is required for the RNA-binding protein ELAVL1/HuR to regulate ferroptosis in hepatic stellate cells | Autophagy | 2018 | 296 |
| 13 | Myocardial Infarction: Symptoms and Treatments | Cell Biochemistry and Biophysics | 2015 | 273 |
| 14 | Central Terminal Sensitization of TRPV1 by Descending Serotonergic Facilitation Modulates Chronic Pain | Neuron | 2014 | 262 |
| 15 | Chronic stress promotes colitis by disturbing the gut microbiota and triggering immune system response | Proceedings of the National Academy of Sciences of the United States of America | 2018 | 261 |
| 16 | Advances in studies of tyrosine kinase inhibitors and their acquired resistance | Molecular Cancer | 2018 | 255 |
| 17 | Small molecule-driven NLRP3 inflammation inhibition via interplay between ubiquitination and autophagy: implications for Parkinson disease | Autophagy | 2019 | 250 |
| 18 | RNA-binding protein ZFP36/TTP protects against ferroptosis by regulating autophagy signaling pathway in hepatic stellate cells | Autophagy | 2020 | 243 |
| 19 | Understanding the Molecular Mechanisms of the Interplay Between Herbal Medicines and Gut Microbiota | Medicinal Research Reviews | 2017 | 241 |
| 20 | Different longitudinal patterns of nucleic acid and serology testing results based on disease severity of COVID-19 patients | Emerging Microbes and Infections | 2020 | 239 |
| 21 | Cabozantinib plus atezolizumab versus sorafenib for advanced hepatocellular carcinoma (COSMIC-312): a multicentre, open-label, randomised, phase 3 trial | Lancet Oncology, The | 2022 | 237 |
| 22 | New synthetic strategies to prepare metal–organic frameworks | Inorganic Chemistry Frontiers | 2018 | 235 |
| 23 | The recent progress of isoxazole in medicinal chemistry | Bioorganic and Medicinal Chemistry | 2018 | 233 |
| 24 | Recent progress in the identification of selective butyrylcholinesterase inhibitors for Alzheimer's disease | European Journal of Medicinal Chemistry | 2017 | 229 |
| 25 | Single‐cell RNA sequencing technologies and applications: A brief overview | Clinical and Translational Medicine | 2022 | 218 |
| 26 | HSP27, 70 and 90, anti-apoptotic proteins, in clinical cancer therapy | International Journal of Oncology | 2014 | 215 |
| 27 | Natural Product Interventions for Chemotherapy and Radiotherapy-Induced Side Effects | Frontiers in Pharmacology | 2018 | 213 |
| 28 | Ginseng-derived nanoparticles alter macrophage polarization to inhibit melanoma growth | | 2019 | 211 |
| 29 | Scutellaria baicalensis Georgi polysaccharide ameliorates DSS-induced ulcerative colitis by improving intestinal barrier function and modulating gut microbiota | International Journal of Biological Macromolecules | 2021 | 211 |
| 30 | Pyruvate kinase type M2 promotes tumour cell exosome release via phosphorylating synaptosome-associated protein 23 | Nature Communications | 2017 | 210 |
| 31 | CSH guidelines for the diagnosis and treatment of drug-induced liver injury | Hepatology International | 2017 | 206 |
| 32 | Overview on Biological Activities and Molecular Characteristics of Sulfated Polysaccharides from Marine Green Algae in Recent Years | Marine Drugs | 2014 | 205 |
| 33 | Metformin Prevents Dopaminergic Neuron Death in MPTP/P-Induced Mouse Model of Parkinson’s Disease via Autophagy and Mitochondrial ROS Clearance | International Journal of Neuropsychopharmacology | 2016 | 202 |
| 34 | Digitally Tunable Microfluidic Bioprinting of Multilayered Cannular Tissues | Advanced Materials | 2018 | 199 |
| 35 | Downregulation of CREB expression in Alzheimer's brain and in Aβ-treated rat hippocampal neurons | Molecular Neurodegeneration | 2011 | 197 |
| 36 | Blocking meningeal lymphatic drainage aggravates Parkinson’s disease-like pathology in mice overexpressing mutated α-synuclein | Translational Neurodegeneration | 2019 | 187 |
| 37 | Efficacy and Safety of Long-Term Universal Salt Iodization on Thyroid Disorders: Epidemiological Evidence from 31 Provinces of Mainland China | Thyroid | 2020 | 185 |
| 38 | Rhein modulates host purine metabolism in intestine through gut microbiota and ameliorates experimental colitis | Theranostics | 2020 | 184 |
| 39 | The immediate impact of the 2019 novel coronavirus (COVID-19) outbreak on subjective sleep status | Sleep Medicine | 2021 | 184 |
| 40 | Effectiveness of Virtual Reality in Nursing Education: Meta-Analysis | Journal of Medical Internet Research | 2020 | 184 |
| 41 | Alternative splicing and cancer: a systematic review | Signal Transduction and Targeted Therapy | 2021 | 183 |
| 42 | Luteolin: A Flavonoid that Has Multiple Cardio-Protective Effects and Its Molecular Mechanisms | Frontiers in Pharmacology | 2017 | 179 |
| 43 | Quercetin hinders microglial activation to alleviate neurotoxicity via the interplay between NLRP3 inflammasome and mitophagy | Redox Biology | 2021 | 179 |
| 44 | Xiexin Tang improves the symptom of type 2 diabetic rats by modulation of the gut microbiota | Scientific Reports | 2018 | 173 |
| 45 | Review on circular RNAs and new insights into their roles in cancer | Computational and Structural Biotechnology Journal | 2021 | 173 |
| 46 | Analgesic and anti-inflammatory properties of brucine and brucine N-oxide extracted from seeds of Strychnos nux-vomica | Journal of Ethnopharmacology | 2003 | 169 |
| 47 | Efficacy and Tolerability of First-Line Cetuximab Plus Leucovorin, Fluorouracil, and Oxaliplatin (FOLFOX-4) Versus FOLFOX-4 in Patients With RAS Wild-Type Metastatic Colorectal Cancer: The Open-Label, Randomized, Phase III TAILOR Trial | Journal of Clinical Oncology | 2018 | 159 |
| 48 | Antibacterial and Hemostatic Thiol-Modified Chitosan-Immobilized AgNPs Composite Sponges | ACS Applied Materials & Interfaces | 2020 | 159 |
| 49 | RNA-binding proteins in tumor progression | Journal of Hematology and Oncology | 2020 | 156 |
| 50 | Congenital Heart Disease: Causes, Diagnosis, Symptoms, and Treatments | Cell Biochemistry and Biophysics | 2015 | 153 |
