| # | Title | Journal | Year | Citations |
|---|
| 1 | Effect of Oral Milrinone on Mortality in Severe Chronic Heart Failure | New England Journal of Medicine | 1991 | 2,137 |
| 2 | Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data | BMJ: British Medical Journal | 2017 | 1,408 |
| 3 | Impact of BAL Data on the Therapy and Outcome of Ventilator-Associated Pneumonia | Chest | 1997 | 940 |
| 4 | Sex Differences in the Management of Coronary Artery Disease | New England Journal of Medicine | 1991 | 847 |
| 5 | Body Fat Content and 25-Hydroxyvitamin D Levels in Healthy Women | Journal of Clinical Endocrinology and Metabolism | 2003 | 535 |
| 6 | Linezolid in Methicillin-Resistant Staphylococcus aureus Nosocomial Pneumonia: A Randomized, Controlled Study | Clinical Infectious Diseases | 2012 | 513 |
| 7 | The cost of treating community-acquired pneumonia | Clinical Therapeutics | 1998 | 488 |
| 8 | Megakaryocytes and platelet-fibrin thrombi characterize multi-organ thrombosis at autopsy in COVID-19: A case series | EClinicalMedicine | 2020 | 465 |
| 9 | Durvalumab With or Without Tremelimumab vs Standard Chemotherapy in First-line Treatment of Metastatic Non–Small Cell Lung Cancer | JAMA Oncology | 2020 | 446 |
| 10 | Effect of Corticosteroids on Treatment Failure Among Hospitalized Patients With Severe Community-Acquired Pneumonia and High Inflammatory Response | JAMA - Journal of the American Medical Association | 2015 | 428 |
| 11 | Patient burden and quality of life in atopic dermatitis in US adults | Annals of Allergy, Asthma and Immunology | 2018 | 383 |
| 12 | First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma | Journal of Translational Medicine | 2018 | 376 |
| 13 | Infective Exacerbations of Chronic Bronchitis | Chest | 1998 | 372 |
| 14 | Reduction in recombinant human erythropoietin doses by the use of chronic intravenous iron supplementation | American Journal of Kidney Diseases | 1995 | 368 |
| 15 | Hospitalization for heart failure in the presence of a normal left ventricular ejection fraction | Journal of the American College of Cardiology | 2004 | 350 |
| 16 | Risk factors for postmenopausal osteoporosis | American Journal of Medicine | 1985 | 333 |
| 17 | Global prevalence and disease burden of vitamin D deficiency: a roadmap for action in low‐ and middle‐income countries | Annals of the New York Academy of Sciences | 2018 | 330 |
| 18 | Amyloid toxicity in Alzheimer’s disease | Reviews in the Neurosciences | 2018 | 312 |
| 19 | Vitamin D supplementation to prevent acute respiratory infections: a systematic review and meta-analysis of aggregate data from randomised controlled trials | Lancet Diabetes and Endocrinology,the | 2021 | 292 |
| 20 | Endoscopic Ultrasonography–Guided Fine-Needle Aspiration Biopsy of Suspected Pancreatic Cancer | Annals of Internal Medicine | 2001 | 287 |
| 21 | The 2011 Dietary Reference Intakes for Calcium and Vitamin D: What Dietetics Practitioners Need to Know⁎⁎This article is a summary of the Institute of Medicine report entitled Dietary Reference Intakes for Calcium and Vitamin D (available at http://www.iom.edu/Reports/2010/Dietary-Reference-Intakes-for-Calcium-and-Vitamin-D.aspx) for dietetics practitioners; a similar summary for clinicians has also been published (Ross AC, Manson JE, Abrams SA, Aloia JF, Brannon PM, Clinton SK, Durazo-Arvizu RA, Gallagher | Journal of the American Dietetic Association | 2011 | 287 |
| 22 | A randomized controlled trial of N-acetylcysteine to prevent contrast nephropathy in cardiac angiography | Kidney International | 2002 | 268 |
| 23 | Carbon monoxide provides protection against hyperoxic lung injury | American Journal of Physiology - Lung Cellular and Molecular Physiology | 1999 | 267 |
| 24 | The safety of intravenous iron dextran in hemodialysis patients | American Journal of Kidney Diseases | 1996 | 263 |
| 25 | Pitfalls in Hemoglobin A1c Measurement: When Results may be Misleading | Journal of General Internal Medicine | 2014 | 261 |
| 26 | Gastric peroral endoscopic myotomy for refractory gastroparesis: first human endoscopic pyloromyotomy (with video) | Gastrointestinal Endoscopy | 2013 | 255 |
| 27 | Invasive diagnostic testing is not needed routinely to manage suspected ventilator-associated pneumonia. | American Journal of Respiratory and Critical Care Medicine | 1994 | 252 |
| 28 | Hemoglobin cycling in hemodialysis patients treated with recombinant human erythropoietin | Kidney International | 2005 | 248 |
| 29 | Cellular Oxygen Toxicity | Journal of Biological Chemistry | 1996 | 237 |
| 30 | Pneumonia Complicating Pregnancy | Clinics in Chest Medicine | 2011 | 235 |
| 31 | Calcitriol in the treatment of postmenopausal osteoporosis | American Journal of Medicine | 1988 | 231 |
| 32 | Regulation of renal urate excretion: A critical review | American Journal of Kidney Diseases | 1998 | 229 |
| 33 | p53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent osteoclastogenesis, and bone remodeling | Journal of Cell Biology | 2006 | 225 |
| 34 | Efficacy of 23-valent pneumococcal vaccine in preventing pneumonia and improving survival in nursing home residents: double blind, randomised and placebo controlled trial | BMJ: British Medical Journal | 2010 | 225 |
| 35 | Relationship of menopause to skeletal and muscle mass | American Journal of Clinical Nutrition | 1991 | 220 |
| 36 | Atopic dermatitis yardstick: Practical recommendations for an evolving therapeutic landscape | Annals of Allergy, Asthma and Immunology | 2018 | 214 |
| 37 | Emergency peripartum hysterectomy: experience at a community teaching hospital | Obstetrics and Gynecology | 2002 | 212 |
| 38 | Calcium Supplementation with and without Hormone Replacement Therapy To Prevent Postmenopausal Bone Loss | Annals of Internal Medicine | 1994 | 210 |
| 39 | The atypical pneumonias: clinical diagnosis and importance | Clinical Microbiology and Infection | 2006 | 210 |
| 40 | Nosocomial Pneumonia | Chest | 2002 | 209 |
| 41 | Visualization of severe acute respiratory syndrome coronavirus 2 invading the human placenta using electron microscopy | American Journal of Obstetrics and Gynecology | 2020 | 189 |
| 42 | Trends in COVID‐19 Risk‐Adjusted Mortality Rates | Journal of Hospital Medicine | 2021 | 188 |
| 43 | The Opioid Crisis: a Comprehensive Overview | Current Pain and Headache Reports | 2018 | 181 |
| 44 | Diagnosis, Genetics, and Therapy of Short Stature in Children: A Growth Hormone Research Society International Perspective | Hormone Research in Paediatrics | 2019 | 181 |
| 45 | Sulfhydryl oxidases: emerging catalysts of protein disulfide bond formation in eukaryotes | Archives of Biochemistry and Biophysics | 2002 | 179 |
| 46 | N-Acetylcysteine In The Prevention Of Radiocontrast-Induced Nephropathy | Journal of the American Society of Nephrology: JASN | 2004 | 175 |
| 47 | Effect of Lanadelumab Compared With Placebo on Prevention of Hereditary Angioedema Attacks | JAMA - Journal of the American Medical Association | 2018 | 174 |
| 48 | A Review of Complication Rates for Anterior Cervical Diskectomy and Fusion (ACDF) | | 2019 | 174 |
| 49 | Self‐assessed physical and mental function of haemodialysis patients | Nephrology Dialysis Transplantation | 2001 | 169 |
| 50 | The Sacrum: Pathologic Spectrum, Multimodality Imaging, and Subspecialty Approach | Radiographics | 2001 | 167 |
