| # | Title | Journal | Year | Citations |
|---|
| 1 | The REDCap consortium: Building an international community of software platform partners | Journal of Biomedical Informatics | 2019 | 11,010 |
| 2 | Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines | Journal of Extracellular Vesicles | 2018 | 6,961 |
| 3 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 4 | Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 | Intensive Care Medicine | 2017 | 4,590 |
| 5 | Genetic studies of body mass index yield new insights for obesity biology | Nature | 2015 | 3,823 |
| 6 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 7 | Clinical Practice Guidelines for the Management of Pain, Agitation, and Delirium in Adult Patients in the Intensive Care Unit | Critical Care Medicine | 2013 | 3,066 |
| 8 | Updated Clinical Classification of Pulmonary Hypertension | Journal of the American College of Cardiology | 2013 | 2,865 |
| 9 | Comparison of global estimates of prevalence and risk factors for peripheral artery disease in 2000 and 2010: a systematic review and analysis | Lancet, The | 2013 | 2,640 |
| 10 | National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: I. The 2014 Diagnosis and Staging Working Group Report | Biology of Blood and Marrow Transplantation | 2015 | 2,636 |
| 11 | Clinician’s Guide to Prevention and Treatment of Osteoporosis | Osteoporosis International | 2014 | 2,549 |
| 12 | Delirium in Mechanically Ventilated Patients | JAMA - Journal of the American Medical Association | 2001 | 2,449 |
| 13 | Outbreak of pneumonia of unknown etiology in Wuhan, China: The mystery and the miracle | Journal of Medical Virology | 2020 | 2,395 |
| 14 | Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas | Gastroenterology | 1994 | 2,329 |
| 15 | Development of the asthma control test☆A survey for assessing asthma control | Journal of Allergy and Clinical Immunology | 2004 | 2,249 |
| 16 | Complement Factor H Variant Increases the Risk of Age-Related Macular Degeneration | Science | 2005 | 2,232 |
| 17 | FDG PET/CT: EANM procedure guidelines for tumour imaging: version 2.0 | European Journal of Nuclear Medicine and Molecular Imaging | 2015 | 2,188 |
| 18 | Cyclooxygenase Regulates Angiogenesis Induced by Colon Cancer Cells | Cell | 1998 | 2,151 |
| 19 | Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2 | Cell | 1995 | 2,144 |
| 20 | A guide to immunometabolism for immunologists | Nature Reviews Immunology | 2016 | 2,100 |
| 21 | Clinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU | Critical Care Medicine | 2018 | 2,074 |
| 22 | SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues | Cell | 2020 | 1,956 |
| 23 | Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease | Nature Reviews Clinical Oncology | 2016 | 1,938 |
| 24 | Updated Clinical Classification of Pulmonary Hypertension | Journal of the American College of Cardiology | 2009 | 1,919 |
| 25 | Consensus statement on concussion in sport—the 5thinternational conference on concussion in sport held in Berlin, October 2016 | British Journal of Sports Medicine | 2017 | 1,903 |
| 26 | Defining the role of common variation in the genomic and biological architecture of adult human height | Nature Genetics | 2014 | 1,818 |
| 27 | Reassessment of Exosome Composition | Cell | 2019 | 1,786 |
| 28 | Consensus statement on concussion in sport: the 4th International Conference on Concussion in Sport held in Zurich, November 2012 | British Journal of Sports Medicine | 2013 | 1,744 |
| 29 | Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer | Cell | 2018 | 1,718 |
| 30 | Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): two randomised trials | Lancet, The | 2011 | 1,711 |
| 31 | Fatal Toxic Effects Associated With Immune Checkpoint Inhibitors | JAMA Oncology | 2018 | 1,625 |
| 32 | Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk | Nature Genetics | 2019 | 1,625 |
| 33 | Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems During the COVID-19 Pandemic | Journal of the American College of Cardiology | 2020 | 1,557 |
| 34 | Targeted Disruption of the Stat1 Gene in Mice Reveals Unexpected Physiologic Specificity in the JAK–STAT Signaling Pathway | Cell | 1996 | 1,537 |
| 35 | The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers | Nature | 2012 | 1,506 |
| 36 | LinkedOmics: analyzing multi-omics data within and across 32 cancer types | Nucleic Acids Research | 2018 | 1,497 |
| 37 | Childhood Functional Gastrointestinal Disorders: Child/Adolescent | Gastroenterology | 2006 | 1,432 |
| 38 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 39 | Matrix Metalloproteinases: Biologic Activity and Clinical Implications | Journal of Clinical Oncology | 2000 | 1,420 |
| 40 | Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study | Lancet, The | 2020 | 1,395 |
| 41 | Heterozygous germline mutations in BMPR2, encoding a TGF-β receptor, cause familial primary pulmonary hypertension | Nature Genetics | 2000 | 1,388 |
| 42 | Renal histopathological analysis of 26 postmortem findings of patients with COVID-19 in China | Kidney International | 2020 | 1,388 |
| 43 | Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV | Nature Communications | 2020 | 1,376 |
| 44 | A comprehensive classification system for lipids | Journal of Lipid Research | 2005 | 1,348 |
| 45 | Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps | Nature Genetics | 2018 | 1,331 |
| 46 | New genetic loci link adipose and insulin biology to body fat distribution | Nature | 2015 | 1,328 |
| 47 | Estimating the global incidence of traumatic brain injury | Journal of Neurosurgery | 2019 | 1,291 |
| 48 | The role of cyclooxygenases in inflammation, cancer, and development | Oncogene | 1999 | 1,289 |
| 49 | Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential | Proceedings of the National Academy of Sciences of the United States of America | 1997 | 1,280 |
| 50 | Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses | Science Translational Medicine | 2017 | 1,279 |
