| # | Title | Journal | Year | Citations |
|---|
| 1 | The Occurrence of Sleep-Disordered Breathing among Middle-Aged Adults | New England Journal of Medicine | 1993 | 9,133 |
| 2 | Prospective Study of the Association between Sleep-Disordered Breathing and Hypertension | New England Journal of Medicine | 2000 | 4,294 |
| 3 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 4 | Ischemic Cell Death in Brain Neurons | Physiological Reviews | 1999 | 2,689 |
| 5 | Obesity and the risk of myocardial infarction in 27 000 participants from 52 countries: a case-control study | Lancet, The | 2005 | 2,414 |
| 6 | Nuclear Export of MicroRNA Precursors | Science | 2004 | 2,348 |
| 7 | A penetration-aspiration scale | Dysphagia | 1996 | 2,116 |
| 8 | Alterations in Brain and Immune Function Produced by Mindfulness Meditation | Psychosomatic Medicine | 2003 | 1,964 |
| 9 | Age- and Gender-Related Test Performance in Community-Dwelling Elderly People: Six-Minute Walk Test, Berg Balance Scale, Timed Up & Go Test, and Gait Speeds | Physical Therapy | 2002 | 1,701 |
| 10 | A Controlled Trial of Sustained-Release Bupropion, a Nicotine Patch, or Both for Smoking Cessation | New England Journal of Medicine | 1999 | 1,495 |
| 11 | Longitudinal Study of Moderate Weight Change and Sleep-Disordered Breathing | JAMA - Journal of the American Medical Association | 2000 | 1,447 |
| 12 | Mop3 Is an Essential Component of the Master Circadian Pacemaker in Mammals | Cell | 2000 | 1,380 |
| 13 | Use of Normal Tissue Complication Probability Models in the Clinic | International Journal of Radiation Oncology Biology Physics | 2010 | 1,376 |
| 14 | Accumulation of miR-155 and BIC RNA in human B cell lymphomas | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 1,295 |
| 15 | The Risk of Bloodstream Infection in Adults With Different Intravascular Devices: A Systematic Review of 200 Published Prospective Studies | Mayo Clinic Proceedings | 2006 | 1,273 |
| 16 | HERG, a human inward rectifier in the voltage-gated potassium channel family | Science | 1995 | 1,183 |
| 17 | The hMre11/hRad50 Protein Complex and Nijmegen Breakage Syndrome: Linkage of Double-Strand Break Repair to the Cellular DNA Damage Response | Cell | 1998 | 1,138 |
| 18 | The Wisconsin Age-related Maculopathy Grading System | Ophthalmology | 1991 | 1,072 |
| 19 | The Alcohol Use Disorders Identification Test (AUDIT): validation of a screening instrument for use in medical settings. | Journal of Studies on Alcohol and Drugs | 1995 | 1,068 |
| 20 | Guidelines for the Prevention of Intravascular Catheter–Related Infections | Infection Control and Hospital Epidemiology | 2002 | 1,024 |
| 21 | Small colony variants: a pathogenic form of bacteria that facilitates persistent and recurrent infections | Nature Reviews Microbiology | 2006 | 1,004 |
| 22 | The association between hepatitis C infection and survival after orthotopic liver transplantation | Gastroenterology | 2002 | 994 |
| 23 | Clinical and economic consequences of ventilator-associated pneumonia: A systematic review | Critical Care Medicine | 2005 | 993 |
| 24 | The DNA Double-Strand Break Repair Gene hMRE11 Is Mutated in Individuals with an Ataxia-Telangiectasia-like Disorder | Cell | 1999 | 986 |
| 25 | Review of the folin phenol protein quantitation method of lowry, rosebrough, farr and randall | Analytical Biochemistry | 1979 | 975 |
| 26 | Prevalence of Hearing Loss in Older Adults in Beaver Dam, Wisconsin: The Epidemiology of Hearing Loss Study | American Journal of Epidemiology | 1998 | 969 |
| 27 | Under the shadow of Tuskegee: African Americans and health care. | American Journal of Public Health | 1997 | 959 |
| 28 | The PAS Superfamily: Sensors of Environmental and Developmental Signals | Annual Review of Pharmacology and Toxicology | 2000 | 959 |
| 29 | Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase | Journal of Virology | 1995 | 957 |
| 30 | Early Diagnosis of Cystic Fibrosis Through Neonatal Screening Prevents Severe Malnutrition and Improves Long-Term Growth | Pediatrics | 2001 | 948 |
| 31 | Erythromycin resistance by ribosome modification | Antimicrobial Agents and Chemotherapy | 1995 | 937 |
| 32 | The Five-year Incidence and Progression of Age-related Maculopathy | Ophthalmology | 1997 | 888 |
| 33 | Multilineage Differentiation from Human Embryonic Stem Cell Lines | Stem Cells | 2001 | 876 |
| 34 | Prognostic value of tumor oxygenation in 397 head and neck tumors after primary radiation therapy. An international multi-center study | Radiotherapy and Oncology | 2005 | 867 |
| 35 | Diagnosis of Invasive Aspergillosis Using a Galactomannan Assay: A Meta-Analysis | Clinical Infectious Diseases | 2006 | 846 |
| 36 | AH RECEPTOR SIGNALING PATHWAYS | Annual Review of Cell and Developmental Biology | 1996 | 840 |
| 37 | Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates | Nature Medicine | 1999 | 801 |
| 38 | The epidemiology of age-related macular degeneration | American Journal of Ophthalmology | 2004 | 794 |
| 39 | Hyperglycemie and Microvascular and Macrovascular Disease in Diabetes | Diabetes Care | 1995 | 789 |
| 40 | What Is Population Health? | American Journal of Public Health | 2003 | 756 |
| 41 | The role of the thalamus in the flow of information to the cortex | Philosophical Transactions of the Royal Society B: Biological Sciences | 2002 | 755 |
| 42 | The Wisconsin Epidemiologic Study of Diabetic Retinopathy | Ophthalmology | 1984 | 731 |
| 43 | Daratumumab monotherapy in patients with treatment-refractory multiple myeloma (SIRIUS): an open-label, randomised, phase 2 trial | Lancet, The | 2016 | 724 |
| 44 | Receptors and Phosphoinositide-Generated Second Messengers | Annual Review of Biochemistry | 1985 | 719 |
| 45 | Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 715 |
| 46 | Interaural time sensitivity in medial superior olive of cat | Journal of Neurophysiology | 1990 | 693 |
| 47 | The winnowing: establishing the squid–vibrio symbiosis | Nature Reviews Microbiology | 2004 | 689 |
| 48 | Epigenomic Analysis of Multilineage Differentiation of Human Embryonic Stem Cells | Cell | 2013 | 689 |
| 49 | Association of Sleep Apnea and Type II Diabetes | American Journal of Respiratory and Critical Care Medicine | 2005 | 670 |
| 50 | The Wisconsin epidemiologic study of diabetic retinopathy: XVII | Ophthalmology | 1998 | 658 |
