| # | Title | Journal | Year | Citations |
|---|
| 1 | Design and validation of a histological scoring system for nonalcoholic fatty liver disease | Hepatology | 2005 | 8,518 |
| 2 | The landscape of somatic copy-number alteration across human cancers | Nature | 2010 | 3,331 |
| 3 | Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 2,852 |
| 4 | Integrative Clinical Genomics of Advanced Prostate Cancer | Cell | 2015 | 2,660 |
| 5 | American Cancer Society Guidelines for Breast Screening with MRI as an Adjunct to Mammography | Ca-A Cancer Journal for Clinicians | 2007 | 2,234 |
| 6 | Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017 | JAMA Surgery | 2017 | 2,099 |
| 7 | Lixisenatide in Patients with Type 2 Diabetes and Acute Coronary Syndrome | New England Journal of Medicine | 2015 | 1,856 |
| 8 | Acetaminophen-induced acute liver failure: Results of a United States multicenter, prospective study | Hepatology | 2005 | 1,688 |
| 9 | Definition, evaluation, and classification of renal osteodystrophy: A position statement from Kidney Disease: Improving Global Outcomes (KDIGO) | Kidney International | 2006 | 1,586 |
| 10 | Incidence and Prevalence of Idiopathic Pulmonary Fibrosis | American Journal of Respiratory and Critical Care Medicine | 2006 | 1,113 |
| 11 | Elevated Uric Acid Increases Blood Pressure in the Rat by a Novel Crystal-Independent Mechanism | Hypertension | 2001 | 1,092 |
| 12 | Effect of Catheter Ablation vs Antiarrhythmic Drug Therapy on Mortality, Stroke, Bleeding, and Cardiac Arrest Among Patients With Atrial Fibrillation | JAMA - Journal of the American Medical Association | 2019 | 953 |
| 13 | Perioperative Bridging Anticoagulation in Patients with Atrial Fibrillation | New England Journal of Medicine | 2015 | 951 |
| 14 | Membranoproliferative Glomerulonephritis Associated with Hepatitis C Virus Infection | New England Journal of Medicine | 1993 | 880 |
| 15 | Polyomavirus-Associated Nephropathy in Renal Transplantation: Interdisciplinary Analyses and Recommendations | Transplantation | 2005 | 842 |
| 16 | MRI Evaluation of the Contralateral Breast in Women with Recently Diagnosed Breast Cancer | New England Journal of Medicine | 2007 | 842 |
| 17 | Germline and Somatic Mutations in Homologous Recombination Genes Predict Platinum Response and Survival in Ovarian, Fallopian Tube, and Peritoneal Carcinomas | Clinical Cancer Research | 2014 | 803 |
| 18 | Androgen Receptor Regulates a Distinct Transcription Program in Androgen-Independent Prostate Cancer | Cell | 2009 | 797 |
| 19 | Adult-onset pulmonary fibrosis caused by mutations in telomerase | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 756 |
| 20 | EZH2 Oncogenic Activity in Castration-Resistant Prostate Cancer Cells Is Polycomb-Independent | Science | 2012 | 748 |
| 21 | Strategies to Prevent Surgical Site Infections in Acute Care Hospitals: 2014 Update | Infection Control and Hospital Epidemiology | 2014 | 746 |
| 22 | The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB–binding protein | Nature Genetics | 1996 | 740 |
| 23 | Nutrition Therapy Recommendations for the Management of Adults With Diabetes | Diabetes Care | 2013 | 702 |
| 24 | The Incidence of Awareness During Anesthesia: A Multicenter United States Study | Anesthesia and Analgesia | 2004 | 679 |
| 25 | A New Definition of Genetic Counseling: National Society of Genetic Counselors’ Task Force Report | Journal of Genetic Counseling | 2006 | 672 |
| 26 | How B and T cells talk to each other | Nature | 1994 | 638 |
| 27 | The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future | Genetics in Medicine | 2013 | 611 |
| 28 | A Common Dominant TLR5 Stop Codon Polymorphism Abolishes Flagellin Signaling and Is Associated with Susceptibility to Legionnaires' Disease | Journal of Experimental Medicine | 2003 | 580 |
| 29 | Nutrition Therapy Recommendations for the Management of Adults With Diabetes | Diabetes Care | 2014 | 565 |
| 30 | Neostigmine for the Treatment of Acute Colonic Pseudo-Obstruction | New England Journal of Medicine | 1999 | 562 |
| 31 | Increasing the reliability and validity of pain intensity measurement in chronic pain patients | Pain | 1993 | 536 |
| 32 | The Lancet women and cardiovascular disease Commission: reducing the global burden by 2030 | Lancet, The | 2021 | 530 |
| 33 | Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial | Lancet Oncology, The | 2015 | 524 |
| 34 | Oxidative capacity and ageing in human muscle | Journal of Physiology | 2000 | 523 |
| 35 | The natural history of hereditary multiple exostoses. | Journal of Bone and Joint Surgery - Series A | 1994 | 523 |
| 36 | Proposal for a New Tool to Evaluate Drug Interaction Cases | Annals of Pharmacotherapy | 2007 | 518 |
| 37 | Chronic lung allograft dysfunction: Definition, diagnostic criteria, and approaches to treatment―A consensus report from the Pulmonary Council of the ISHLT | Journal of Heart and Lung Transplantation | 2019 | 518 |
| 38 | Brentuximab vedotin with chemotherapy for CD30-positive peripheral T-cell lymphoma (ECHELON-2): a global, double-blind, randomised, phase 3 trial | Lancet, The | 2019 | 517 |
| 39 | Secondary Somatic Mutations RestoringBRCA1/2Predict Chemotherapy Resistance in Hereditary Ovarian Carcinomas | Journal of Clinical Oncology | 2011 | 513 |
| 40 | Idiopathic pulmonary fibrosis in US Medicare beneficiaries aged 65 years and older: incidence, prevalence, and survival, 2001–11 | Lancet Respiratory Medicine,the | 2014 | 513 |
| 41 | Cowden Syndrome and the PTEN Hamartoma Tumor Syndrome: Systematic Review and Revised Diagnostic Criteria | Journal of the National Cancer Institute | 2013 | 483 |
| 42 | Global and National Burden of Diseases and Injuries Among Children and Adolescents Between 1990 and 2013 | JAMA Pediatrics | 2016 | 479 |
| 43 | Prevalence and prognostic significance of Flt3 internal tandem duplication in pediatric acute myeloid leukemia | Blood | 2001 | 465 |
| 44 | Effects of intensive glucose lowering on brain structure and function in people with type 2 diabetes (ACCORD MIND): a randomised open-label substudy | Lancet Neurology, The | 2011 | 455 |
| 45 | Fractures Attributable to Osteoporosis: Report from the National Osteoporosis Foundation | Journal of Bone and Mineral Research | 1997 | 452 |
| 46 | Fulminant hepatic failure: Summary of a workshop | Hepatology | 1995 | 445 |
| 47 | Treatment of Idiopathic Pulmonary Fibrosis With Ambrisentan | Annals of Internal Medicine | 2013 | 437 |
| 48 | Pain Assessment in the Nonverbal Patient: Position Statement with Clinical Practice Recommendations | Pain Management Nursing | 2006 | 432 |
| 49 | Contribution of Bone Marrow-Derived Cells to Skin: Collagen Deposition and Wound Repair | Stem Cells | 2004 | 422 |
| 50 | A practice guideline from the American College of Medical Genetics and Genomics and the National Society of Genetic Counselors: referral indications for cancer predisposition assessment | Genetics in Medicine | 2015 | 418 |
