| # | Title | Journal | Year | Citations |
|---|
| 1 | The Female Sexual Function Index (FSFI): A Multidimensional Self-Report Instrument for the Assessment of Female Sexual Function | Journal of Sex and Marital Therapy | 2000 | 4,908 |
| 2 | A Randomized Trial of Intensive versus Standard Blood-Pressure Control | New England Journal of Medicine | 2015 | 4,880 |
| 3 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 4 | The Eighth Edition AJCC Cancer Staging Manual: Continuing to build a bridge from a population‐based to a more “personalized” approach to cancer staging | Ca-A Cancer Journal for Clinicians | 2017 | 3,940 |
| 5 | Allergic Rhinitis and its Impact on Asthma (ARIA) 2008* | Allergy: European Journal of Allergy and Clinical Immunology | 2008 | 3,827 |
| 6 | Mutations in LRRK2 Cause Autosomal-Dominant Parkinsonism with Pleomorphic Pathology | Neuron | 2004 | 2,653 |
| 7 | Cardiovascular Effects of Intensive Lifestyle Intervention in Type 2 Diabetes | New England Journal of Medicine | 2013 | 2,294 |
| 8 | The Loss of Skeletal Muscle Strength, Mass, and Quality in Older Adults: The Health, Aging and Body Composition Study | Journals of Gerontology - Series A Biological Sciences and Medical Sciences | 2006 | 2,216 |
| 9 | NF-κB activation by tumour necrosis factor requires the Akt serine–threonine kinase | Nature | 1999 | 2,069 |
| 10 | Estrogen plus Progestin and the Risk of Coronary Heart Disease | New England Journal of Medicine | 2003 | 1,928 |
| 11 | Transfusion of Plasma, Platelets, and Red Blood Cells in a 1:1:1 vs a 1:1:2 Ratio and Mortality in Patients With Severe Trauma | JAMA - Journal of the American Medical Association | 2015 | 1,874 |
| 12 | Hyperglycemia: An Independent Marker of In-Hospital Mortality in Patients with Undiagnosed Diabetes | Journal of Clinical Endocrinology and Metabolism | 2002 | 1,783 |
| 13 | Melanin Pigmentation in Mammalian Skin and Its Hormonal Regulation | Physiological Reviews | 2004 | 1,666 |
| 14 | Cardiovascular Disease Outcomes During 6.8 Years of Hormone Therapy | JAMA - Journal of the American Medical Association | 2002 | 1,586 |
| 15 | Obesity and Kidney Disease: Hidden Consequences of the Epidemic | American Journal of Nephrology | 2017 | 1,557 |
| 16 | Autoimmunity to type II collagen an experimental model of arthritis. | Journal of Experimental Medicine | 1977 | 1,548 |
| 17 | Hyperglycemic Crises in Adult Patients With Diabetes | Diabetes Care | 2009 | 1,466 |
| 18 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 19 | Reduction in Weight and Cardiovascular Disease Risk Factors in Individuals With Type 2 Diabetes: One-year results of the Look AHEAD trial | Diabetes Care | 2007 | 1,369 |
| 20 | Acute lymphoblastic leukaemia | Lancet, The | 2008 | 1,308 |
| 21 | Comparison of the Release of Adipokines by Adipose Tissue, Adipose Tissue Matrix, and Adipocytes from Visceral and Subcutaneous Abdominal Adipose Tissues of Obese Humans | Endocrinology | 2004 | 1,281 |
| 22 | Very Low Birth Weight Outcomes of the National Institute of Child Health and Human Development Neonatal Research Network, January 1995 Through December 1996 | Pediatrics | 2001 | 1,272 |
| 23 | Expression of Multidrug Resistance Gene in Human Cancers | Journal of the National Cancer Institute | 1989 | 1,214 |
| 24 | Maternal and Perinatal Outcomes Associated with a Trial of Labor after Prior Cesarean Delivery | New England Journal of Medicine | 2004 | 1,166 |
| 25 | Hypoglycemia and Diabetes: A Report of a Workgroup of the American Diabetes Association and The Endocrine Society | Diabetes Care | 2013 | 1,125 |
| 26 | Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture | Nature Genetics | 2012 | 1,100 |
| 27 | ACG Clinical Guideline: Treatment of Helicobacter pylori Infection | American Journal of Gastroenterology | 2017 | 1,084 |
| 28 | Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells | Nature | 1996 | 1,059 |
| 29 | Treating Childhood Acute Lymphoblastic Leukemia without Cranial Irradiation | New England Journal of Medicine | 2009 | 1,059 |
| 30 | Revised nomenclature for avian telencephalon and some related brainstem nuclei | Journal of Comparative Neurology | 2004 | 1,054 |
| 31 | Enteral Versus Parenteral Feeding Effects on Septic Morbidity After Blunt and Penetrating Abdominal Trauma | Annals of Surgery | 1992 | 1,048 |
| 32 | Sodium Reduction and Weight Loss in the Treatment of Hypertension in Older Persons | JAMA - Journal of the American Medical Association | 1998 | 1,048 |
| 33 | Time to Initiation of Fluconazole Therapy Impacts Mortality in Patients with Candidemia: A Multi‐Institutional Study | Clinical Infectious Diseases | 2006 | 1,026 |
| 34 | Neurodevelopmental and Functional Outcomes of Extremely Low Birth Weight Infants in the National Institute of Child Health and Human Development Neonatal Research Network, 1993-1994 | Pediatrics | 2000 | 999 |
| 35 | Jak2 Is Essential for Signaling through a Variety of Cytokine Receptors | Cell | 1998 | 987 |
| 36 | Guidelines of care for the management of atopic dermatitis | Journal of the American Academy of Dermatology | 2014 | 970 |
| 37 | Prognostic Value of Usual Gait Speed in Well‐Functioning Older People—Results from the Health, Aging and Body Composition Study | Journal of the American Geriatrics Society | 2005 | 940 |
| 38 | IgA Nephropathy | New England Journal of Medicine | 2013 | 936 |
| 39 | Maternal morbidity and mortality in 442 pregnancies with hemolysis, elevated liver enzymes, and low platelets (HELLP syndrome) | American Journal of Obstetrics and Gynecology | 1993 | 932 |
| 40 | Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits | Nature Genetics | 2018 | 924 |
| 41 | Calcium plus Vitamin D Supplementation and the Risk of Colorectal Cancer | New England Journal of Medicine | 2006 | 907 |
| 42 | LKB1 modulates lung cancer differentiation and metastasis | Nature | 2007 | 907 |
| 43 | Differential loss of striatal projection neurons in Huntington disease. | Proceedings of the National Academy of Sciences of the United States of America | 1988 | 895 |
| 44 | Acute lymphoblastic leukaemia | Lancet, The | 2013 | 879 |
| 45 | Effect of Prolonged Methylprednisolone Therapy in Unresolving Acute Respiratory Distress Syndrome | JAMA - Journal of the American Medical Association | 1998 | 853 |
| 46 | MicroRNA Expression Signature and Antisense-Mediated Depletion Reveal an Essential Role of MicroRNA in Vascular Neointimal Lesion Formation | Circulation Research | 2007 | 848 |
| 47 | Exemestane for Breast-Cancer Prevention in Postmenopausal Women | New England Journal of Medicine | 2011 | 847 |
| 48 | A versatile means of intracellular labeling: injection of biocytin and its detection with avidin conjugates | Journal of Neuroscience Methods | 1988 | 846 |
| 49 | The Metabolic Syndrome, Inflammation, and Risk of Cognitive Decline | JAMA - Journal of the American Medical Association | 2004 | 846 |
| 50 | MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy | Cancer | 2014 | 838 |
