| The blood-brain barrier in health and chronic neurodegenerative disorders | Neuron | 2008 | 2.2K |
| Functions of RANKL/RANK/OPG in bone modeling and remodeling | Archives of Biochemistry and Biophysics | 2008 | 1K |
| Inappropriate implantable cardioverter-defibrillator shocks in MADIT II: frequency, mechanisms, predictors, and survival impact | Journal of the American College of Cardiology | 2008 | 612 |
| Core outcome domains and measures for pediatric acute and chronic/recurrent pain clinical trials: PedIMMPACT recommendations | Journal of Pain | 2008 | 585 |
| apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain | Journal of Clinical Investigation | 2008 | 509 |
| Keap1/Nrf2 signaling regulates oxidative stress tolerance and lifespan in Drosophila | Developmental Cell | 2008 | 442 |
| Risk stratification for primary implantation of a cardioverter-defibrillator in patients with ischemic left ventricular dysfunction | Journal of the American College of Cardiology | 2008 | 390 |
| Connexin 43 hemichannels are permeable to ATP | Journal of Neuroscience | 2008 | 385 |
| SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease | American Journal of Respiratory and Critical Care Medicine | 2008 | 385 |
| Gene expression changes in the course of normal brain aging are sexually dimorphic | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 377 |
| A phase I/IItrial of MYO-029 in adult subjects with muscular dystrophy | Annals of Neurology | 2008 | 357 |
| Long QT syndrome | Journal of the American College of Cardiology | 2008 | 352 |
| Phase 2 study of lenalidomide in transfusion-dependent, low-risk, and intermediate-1 risk myelodysplastic syndromes with karyotypes other than deletion 5q | Blood | 2008 | 351 |
| Fracture displacement and screw cutout after open reduction and locked plate fixation of proximal humeral fractures [corrected] | Journal of Bone and Joint Surgery - Series A | 2008 | 342 |
| ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration | Nature Neuroscience | 2008 | 341 |
| Radiation-induced IFN-gamma production within the tumor microenvironment influences antitumor immunity | Journal of Immunology | 2008 | 336 |
| Disparities in diagnosis and access to health services for children with autism: data from the National Survey of Children's Health | Journal of Developmental and Behavioral Pediatrics | 2008 | 334 |
| Dimorphic effects of Notch signaling in bone homeostasis | Nature Medicine | 2008 | 322 |
| The proteomes of human parotid and submandibular/sublingual gland salivas collected as the ductal secretions | Journal of Proteome Research | 2008 | 321 |
| Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells | American Journal of Physiology - Lung Cellular and Molecular Physiology | 2008 | 319 |
| High-throughput SHAPE analysis reveals structures in HIV-1 genomic RNA strongly conserved across distinct biological states | PLoS Biology | 2008 | 313 |
| Cardiovascular risk factors and the metabolic syndrome in pediatric nonalcoholic fatty liver disease | Circulation | 2008 | 282 |
| RyR1 S-nitrosylation underlies environmental heat stroke and sudden death in Y522S RyR1 knockin mice | Cell | 2008 | 255 |
| Histone deacetylase 6 interacts with the microtubule-associated protein tau | Journal of Neurochemistry | 2008 | 251 |
| Neonatal chimerization with human glial progenitor cells can both remyelinate and rescue the otherwise lethally hypomyelinated shiverer mouse | Cell Stem Cell | 2008 | 243 |
