| # | Title | Journal | Year | Citations |
|---|
| 1 | Prophylactic Implantation of a Defibrillator in Patients with Myocardial Infarction and Reduced Ejection Fraction | New England Journal of Medicine | 2002 | 6,199 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 3 | Screening for Depression in Well Older Adults: Evaluation of a Short Form of the CES-D | American Journal of Preventive Medicine | 1994 | 4,008 |
| 4 | A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β | Science Translational Medicine | 2012 | 3,514 |
| 5 | Sleep Drives Metabolite Clearance from the Adult Brain | Science | 2013 | 3,478 |
| 6 | The interpersonal theory of suicide. | Psychological Review | 2010 | 3,406 |
| 7 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 8 | Cardiac-Resynchronization Therapy for the Prevention of Heart-Failure Events | New England Journal of Medicine | 2009 | 2,716 |
| 9 | The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders | Neuron | 2008 | 2,712 |
| 10 | Revised International Prognostic Scoring System for Myelodysplastic Syndromes | Blood | 2012 | 2,458 |
| 11 | Clinical Practice Guideline for the Use of Antimicrobial Agents in Neutropenic Patients with Cancer: 2010 Update by the Infectious Diseases Society of America | Clinical Infectious Diseases | 2011 | 2,434 |
| 12 | Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study | Lancet Oncology, The | 2009 | 2,404 |
| 13 | CTCAE v3.0: development of a comprehensive grading system for the adverse effects of cancer treatment | Seminars in Radiation Oncology | 2003 | 2,277 |
| 14 | Calcium, ATP, and ROS: a mitochondrial love-hate triangle | American Journal of Physiology - Cell Physiology | 2004 | 2,110 |
| 15 | Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS | Nature | 2014 | 1,989 |
| 16 | The role of mononuclear phagocytes in HTLV-III/LAV infection | Science | 1986 | 1,956 |
| 17 | Projected number of people with Parkinson disease in the most populous nations, 2005 through 2030 | Neurology | 2007 | 1,944 |
| 18 | Getting started with yeast | Methods in Enzymology | 2002 | 1,896 |
| 19 | Screening for depression in well older adults: evaluation of a short form of the CES-D (Center for Epidemiologic Studies Depression Scale) | American Journal of Preventive Medicine | 1994 | 1,817 |
| 20 | Multiple Wearable Sensors in Parkinson and Huntington Disease Individuals: A Pilot Study in Clinic and at Home | Digital Biomarkers | 2017 | 1,794 |
| 21 | Prevention of VTE in Nonsurgical Patients | Chest | 2012 | 1,780 |
| 22 | MovementDisorder Society Task Force report on the Hoehn and Yahr staging scale: Status and recommendations TheMovementDisorder Society Task Force on rating scales for Parkinson's disease | Movement Disorders | 2004 | 1,739 |
| 23 | Prevention of VTE in Orthopedic Surgery Patients | Chest | 2012 | 1,723 |
| 24 | Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method | Nature Protocols | 2006 | 1,700 |
| 25 | Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias | Nature Genetics | 1996 | 1,663 |
| 26 | Stereotactic body radiation therapy: The report of AAPM Task Group 101 | Medical Physics | 2010 | 1,616 |
| 27 | Guidelines for the Diagnosis and Management of Food Allergy in the United States: Summary of the NIAID-Sponsored Expert Panel Report | Journal of Allergy and Clinical Immunology | 2010 | 1,614 |
| 28 | Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter | Nature | 2000 | 1,491 |
| 29 | Long-term safety and activity of axicabtagene ciloleucel in refractory large B-cell lymphoma (ZUMA-1): a single-arm, multicentre, phase 1–2 trial | Lancet Oncology, The | 2019 | 1,467 |
| 30 | Decitabine improves patient outcomes in myelodysplastic syndromes | Cancer | 2006 | 1,447 |
| 31 | The Treat-to-Target Trial: Randomized addition of glargine or human NPH insulin to oral therapy of type 2 diabetic patients | Diabetes Care | 2003 | 1,430 |
| 32 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 33 | Functions of RANKL/RANK/OPG in bone modeling and remodeling | Archives of Biochemistry and Biophysics | 2008 | 1,335 |
| 34 | Effects of Tocopherol and Deprenyl on the Progression of Disability in Early Parkinson's Disease | New England Journal of Medicine | 1993 | 1,283 |
| 35 | RAGE mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain | Nature Medicine | 2003 | 1,277 |
| 36 | The Glymphatic System: A Beginner’s Guide | Neurochemical Research | 2015 | 1,266 |
| 37 | Association of an Educational Program in Mindful Communication With Burnout, Empathy, and Attitudes Among Primary Care Physicians | JAMA - Journal of the American Medical Association | 2009 | 1,228 |
| 38 | Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging | Neuron | 2010 | 1,192 |
| 39 | Memantine Treatment in Patients With Moderate to Severe Alzheimer Disease Already Receiving Donepezil | JAMA - Journal of the American Medical Association | 2004 | 1,186 |
| 40 | Reduction in Inappropriate Therapy and Mortality through ICD Programming | New England Journal of Medicine | 2012 | 1,186 |
| 41 | Generalist plus Specialist Palliative Care — Creating a More Sustainable Model | New England Journal of Medicine | 2013 | 1,167 |
| 42 | Intraperitoneal Cisplatin plus Intravenous Cyclophosphamide versus Intravenous Cisplatin plus Intravenous Cyclophosphamide for Stage III Ovarian Cancer | New England Journal of Medicine | 1996 | 1,157 |
| 43 | Immediate Hormonal Therapy Compared with Observation after Radical Prostatectomy and Pelvic Lymphadenectomy in Men with Node-Positive Prostate Cancer | New England Journal of Medicine | 1999 | 1,154 |
| 44 | Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease | Lancet, The | 1994 | 1,142 |
| 45 | Atopic dermatitis | Nature Reviews Disease Primers | 2018 | 1,140 |
| 46 | Uniquely Hominid Features of Adult Human Astrocytes | Journal of Neuroscience | 2009 | 1,112 |
| 47 | Reactive astrocyte nomenclature, definitions, and future directions | Nature Neuroscience | 2021 | 1,098 |
| 48 | Pulmonary effects of inhaled ultrafine particles | International Archives of Occupational and Environmental Health | 2000 | 1,065 |
| 49 | A call for transparent reporting to optimize the predictive value of preclinical research | Nature | 2012 | 1,055 |
| 50 | The State of US Health, 1990-2016 | JAMA - Journal of the American Medical Association | 2018 | 1,042 |
