# | Title | Journal | Year | Citations |
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1 | PD-1 Blockade in Tumors with Mismatch-Repair Deficiency | New England Journal of Medicine | 2015 | 7,696 |
2 | Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade | Science | 2017 | 4,945 |
3 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
4 | Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): Explanation and Elaboration | PLoS Medicine | 2007 | 3,710 |
5 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
6 | Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer | New England Journal of Medicine | 2018 | 3,097 |
7 | Clonal Integration of a Polyomavirus in Human Merkel Cell Carcinoma | Science | 2008 | 2,774 |
8 | Ferroptosis: process and function | Cell Death and Differentiation | 2016 | 2,270 |
9 | The Mutational Landscape of Head and Neck Squamous Cell Carcinoma | Science | 2011 | 2,225 |
10 | The Beclin 1 network regulates autophagy and apoptosis | Cell Death and Differentiation | 2011 | 1,972 |
11 | Head and neck cancer | Lancet, The | 2008 | 1,732 |
12 | Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer | Cell | 2015 | 1,485 |
13 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
14 | Using Multiplexed Assays of Oncogenic Drivers in Lung Cancers to Select Targeted Drugs | JAMA - Journal of the American Medical Association | 2014 | 1,386 |
15 | Autophagy promotes ferroptosis by degradation of ferritin | Autophagy | 2016 | 1,318 |
16 | Activation of the p62‐Keap1‐NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells | Hepatology | 2016 | 1,263 |
17 | Lisocabtagene maraleucel for patients with relapsed or refractory large B-cell lymphomas (TRANSCEND NHL 001): a multicentre seamless design study | Lancet, The | 2020 | 1,224 |
18 | Nomenclature Revision for Encapsulated Follicular Variant of Papillary Thyroid Carcinoma | JAMA Oncology | 2016 | 1,192 |
19 | Levels of TGF-α and EGFR Protein in Head and Neck Squamous Cell Carcinoma and Patient Survival | Journal of the National Cancer Institute | 1998 | 1,034 |
20 | PAMPs and DAMPs: signal 0s that spur autophagy and immunity | Immunological Reviews | 2012 | 899 |
21 | Randomized, Multinational, Phase III Study of Docetaxel Plus Platinum Combinations Versus Vinorelbine Plus Cisplatin for Advanced Non–Small-Cell Lung Cancer: The TAX 326 Study Group | Journal of Clinical Oncology | 2003 | 881 |
22 | Endocytosis, intracellular sorting, and processing of exosomes by dendritic cells | Blood | 2004 | 868 |
23 | Design of the prostate, lung, colorectal and ovarian (PLCO) cancer screening trial | Contemporary Clinical Trials | 2000 | 854 |
24 | A2A adenosine receptor protects tumors from antitumor T cells | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 837 |
25 | Atezolizumab plus nab-paclitaxel as first-line treatment for unresectable, locally advanced or metastatic triple-negative breast cancer (IMpassion130): updated efficacy results from a randomised, double-blind, placebo-controlled, phase 3 trial | Lancet Oncology, The | 2020 | 826 |
26 | Endogenous HMGB1 regulates autophagy | Journal of Cell Biology | 2010 | 819 |
27 | DNA–based immunization by in vivo transfection of dendritic cells | Nature Medicine | 1996 | 814 |
28 | Efficacy of romiplostim in patients with chronic immune thrombocytopenic purpura: a double-blind randomised controlled trial | Lancet, The | 2008 | 784 |
29 | Adjuvant Olaparib for Patients with BRCA1- or BRCA2-Mutated Breast Cancer | New England Journal of Medicine | 2021 | 764 |
30 | Interleukin-17 promotes angiogenesis and tumor growth | Blood | 2003 | 743 |
31 | Gene Expression Alterations in Prostate Cancer Predicting Tumor Aggression and Preceding Development of Malignancy | Journal of Clinical Oncology | 2004 | 674 |
32 | LAG3 (CD223) as a cancer immunotherapy target | Immunological Reviews | 2017 | 664 |
33 | Five-year survival outcomes for patients with advanced melanoma treated with pembrolizumab in KEYNOTE-001 | Annals of Oncology | 2019 | 641 |
34 | Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1α | Oncogene | 2009 | 628 |
35 | T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 625 |
36 | Socioeconomic Status and Chronic Stress: Does Stress Account for SES Effects on Health? | Annals of the New York Academy of Sciences | 1999 | 624 |
37 | Neutrophil elastase–mediated degradation of IRS-1 accelerates lung tumor growth | Nature Medicine | 2010 | 613 |
38 | A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis | Nature | 2006 | 601 |
39 | Epidermal Growth Factor Receptor Biology in Head and Neck Cancer | Journal of Clinical Oncology | 2006 | 600 |
40 | DNA Repair and Mutagenesis | Journal of Clinical Oncology | 2005 | 591 |
41 | Energy Metabolism in Human Pluripotent Stem Cells and Their Differentiated Counterparts | PLoS ONE | 2011 | 574 |
42 | Why do viruses cause cancer? Highlights of the first century of human tumour virology | Nature Reviews Cancer | 2010 | 569 |
43 | Immunology and Immunotherapy of Head and Neck Cancer | Journal of Clinical Oncology | 2015 | 566 |
44 | The grateful dead: damage‐associated molecular pattern molecules and reduction/oxidation regulate immunity | Immunological Reviews | 2007 | 565 |
45 | Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 564 |
46 | The role of BRAF V600 mutation in melanoma | Journal of Translational Medicine | 2012 | 563 |
47 | Cancer vaccines: between the idea and the reality | Nature Reviews Immunology | 2003 | 562 |
48 | Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8 + T Cell Exhaustion | Immunity | 2016 | 560 |
49 | Tumor-Derived Exosomes and Their Role in Cancer Progression | Advances in Clinical Chemistry | 2016 | 549 |
50 | Inside, outside, upside down: damage-associated molecular-pattern molecules (DAMPs) and redox | Trends in Immunology | 2007 | 534 |