| # | Title | Journal | Year | Citations |
|---|
| 1 | 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer | Thyroid | 2016 | 10,674 |
| 2 | Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines | Journal of Extracellular Vesicles | 2018 | 6,961 |
| 3 | Erlotinib in Previously Treated Non–Small-Cell Lung Cancer | New England Journal of Medicine | 2005 | 5,267 |
| 4 | Development of an upper extremity outcome measure: The DASH (disabilities of the arm, shoulder, and head) | | 1996 | 4,131 |
| 5 | A human colon cancer cell capable of initiating tumour growth in immunodeficient mice | Nature | 2007 | 3,765 |
| 6 | Comparison of Upper Gastrointestinal Toxicity of Rofecoxib and Naproxen in Patients with Rheumatoid Arthritis | New England Journal of Medicine | 2000 | 3,651 |
| 7 | Deep Brain Stimulation for Treatment-Resistant Depression | Neuron | 2005 | 3,560 |
| 8 | Impact of COVID-19 pandemic on mental health in the general population: A systematic review | Journal of Affective Disorders | 2020 | 3,399 |
| 9 | Decoding tumour phenotype by noninvasive imaging using a quantitative radiomics approach | Nature Communications | 2014 | 3,355 |
| 10 | The landscape of somatic copy-number alteration across human cancers | Nature | 2010 | 3,331 |
| 11 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 12 | Modulation of oxidative stress as an anticancer strategy | Nature Reviews Drug Discovery | 2013 | 2,735 |
| 13 | The 2005 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma | American Journal of Surgical Pathology | 2005 | 2,334 |
| 14 | Recommendations for Noninvasive Evaluation of Native Valvular Regurgitation | Journal of the American Society of Echocardiography | 2017 | 2,269 |
| 15 | Functional Disability 5 Years after Acute Respiratory Distress Syndrome | New England Journal of Medicine | 2011 | 2,228 |
| 16 | The evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer: recommendations by an International TILs Working Group 2014 | Annals of Oncology | 2015 | 2,122 |
| 17 | The Law of Attrition | Journal of Medical Internet Research | 2005 | 2,113 |
| 18 | One-Year Outcomes in Survivors of the Acute Respiratory Distress Syndrome | New England Journal of Medicine | 2003 | 2,073 |
| 19 | The development and initial validation of the systemic lupus international collaborating clinics/American college of rheumatology damage index for systemic lupus erythematosus | Arthritis and Rheumatism | 1996 | 2,042 |
| 20 | STOP Questionnaire | Anesthesiology | 2008 | 1,950 |
| 21 | Initiation of Inappropriate Antimicrobial Therapy Results in a Fivefold Reduction of Survival in Human Septic Shock | Chest | 2009 | 1,941 |
| 22 | A longitudinal study on the mental health of general population during the COVID-19 epidemic in China | Brain, Behavior, and Immunity | 2020 | 1,880 |
| 23 | Hepatocellular carcinoma | Nature Reviews Disease Primers | 2016 | 1,863 |
| 24 | Core outcome domains for chronic pain clinical trials: IMMPACT recommendations | Pain | 2003 | 1,850 |
| 25 | Erlotinib in Lung Cancer — Molecular and Clinical Predictors of Outcome | New England Journal of Medicine | 2005 | 1,787 |
| 26 | Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes | Nature | 2012 | 1,741 |
| 27 | Revised American Thyroid Association Guidelines for the Management of Medullary Thyroid Carcinoma | Thyroid | 2015 | 1,738 |
| 28 | Outcome of Heart Failure with Preserved Ejection Fraction in a Population-Based Study | New England Journal of Medicine | 2006 | 1,710 |
| 29 | Caspase Functions in Cell Death and Disease | Cold Spring Harbor Perspectives in Biology | 2013 | 1,660 |
| 30 | Time to Treatment With Endovascular Thrombectomy and Outcomes From Ischemic Stroke: A Meta-analysis | JAMA - Journal of the American Medical Association | 2016 | 1,617 |
| 31 | Diabetic Neuropathies: A statement by the American Diabetes Association | Diabetes Care | 2005 | 1,599 |
| 32 | Differentiation of Embryonic Stem Cells to Clinically Relevant Populations: Lessons from Embryonic Development | Cell | 2008 | 1,567 |
| 33 | SARS Control and Psychological Effects of Quarantine, Toronto, Canada | Emerging Infectious Diseases | 2004 | 1,567 |
| 34 | Teaching Surgical Skills — Changes in the Wind | New England Journal of Medicine | 2006 | 1,492 |
| 35 | International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study | Lancet, The | 2018 | 1,487 |
| 36 | The genetic basis of early T-cell precursor acute lymphoblastic leukaemia | Nature | 2012 | 1,430 |
| 37 | CONSORT-EHEALTH: Improving and Standardizing Evaluation Reports of Web-based and Mobile Health Interventions | Journal of Medical Internet Research | 2011 | 1,394 |
| 38 | Evidence-Based Diagnosis, Staging, and Treatment of Patients With Hepatocellular Carcinoma | Gastroenterology | 2016 | 1,365 |
| 39 | Acute respiratory distress syndrome | Nature Reviews Disease Primers | 2019 | 1,364 |
| 40 | Early palliative care for patients with advanced cancer: a cluster-randomised controlled trial | Lancet, The | 2014 | 1,361 |
| 41 | Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population | Nature | 2008 | 1,299 |
| 42 | EAU Guidelines on Prostate Cancer. Part 1: Screening, Diagnosis, and Treatment of Clinically Localised Disease | European Urology | 2011 | 1,299 |
| 43 | Guidelines for the Treatment of Hypothyroidism: Prepared by the American Thyroid Association Task Force on Thyroid Hormone Replacement | Thyroid | 2014 | 1,283 |
| 44 | Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray | Epigenetics | 2013 | 1,276 |
| 45 | Rucaparib maintenance treatment for recurrent ovarian carcinoma after response to platinum therapy (ARIEL3): a randomised, double-blind, placebo-controlled, phase 3 trial | Lancet, The | 2017 | 1,261 |
| 46 | Porphysome nanovesicles generated by porphyrin bilayers for use as multimodal biophotonic contrast agents | Nature Materials | 2011 | 1,219 |
| 47 | Pandemics in the Age of Twitter: Content Analysis of Tweets during the 2009 H1N1 Outbreak | PLoS ONE | 2010 | 1,209 |
| 48 | High-Frequency Oscillatory Ventilation in Adults | Chest | 2004 | 1,201 |
| 49 | Consensus Guidelines for the Management of Postoperative Nausea and Vomiting | Anesthesia and Analgesia | 2014 | 1,200 |
| 50 | Nomenclature Revision for Encapsulated Follicular Variant of Papillary Thyroid Carcinoma | JAMA Oncology | 2016 | 1,192 |
