| # | Title | Journal | Year | Citations |
|---|
| 1 | The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis | Arthritis and Rheumatism | 1988 | 18,339 |
| 2 | A 12-Item Short-Form Health Survey | Medical Care | 1996 | 14,204 |
| 3 | A More Accurate Method To Estimate Glomerular Filtration Rate from Serum Creatinine: A New Prediction Equation | Annals of Internal Medicine | 1999 | 13,300 |
| 4 | The MOS 36-Item Short-Form Health Survey (SF-36) | Medical Care | 1993 | 5,797 |
| 5 | Using Standardized Serum Creatinine Values in the Modification of Diet in Renal Disease Study Equation for Estimating Glomerular Filtration Rate | Annals of Internal Medicine | 2006 | 4,606 |
| 6 | Carotid-Artery Intima and Media Thickness as a Risk Factor for Myocardial Infarction and Stroke in Older Adults | New England Journal of Medicine | 1999 | 4,291 |
| 7 | The MOS 36-ltem Short-Form Health Survey (SF-36): III. Tests of Data Quality, Scaling Assumptions, and Reliability Across Diverse Patient Groups | Medical Care | 1994 | 3,992 |
| 8 | Incidence and Economic Burden of Osteoporosis-Related Fractures in the United States, 2005-2025 | Journal of Bone and Mineral Research | 2007 | 3,248 |
| 9 | A Reversible Posterior Leukoencephalopathy Syndrome | New England Journal of Medicine | 1996 | 3,141 |
| 10 | Definition and classification of chronic kidney disease: A position statement from Kidney Disease: Improving Global Outcomes (KDIGO) | Kidney International | 2005 | 2,836 |
| 11 | The Protective Effects of Estrogen on the Cardiovascular System | New England Journal of Medicine | 1999 | 2,653 |
| 12 | Assessing Kidney Function — Measured and Estimated Glomerular Filtration Rate | New England Journal of Medicine | 2006 | 2,528 |
| 13 | Cross-Validation of Item Selection and Scoring for the SF-12 Health Survey in Nine Countries | Journal of Clinical Epidemiology | 1998 | 2,428 |
| 14 | Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis | Science | 2009 | 2,302 |
| 15 | Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening | Cell | 2009 | 2,200 |
| 16 | Quantitative Synthesis in Systematic Reviews | Annals of Internal Medicine | 1997 | 2,189 |
| 17 | Overview of the SF-36 Health Survey and the International Quality of Life Assessment (IQOLA) Project | Journal of Clinical Epidemiology | 1998 | 2,094 |
| 18 | Effect of losartan compared with captopril on mortality in patients with symptomatic heart failure: randomised trial—the Losartan Heart Failure Survival Study ELITE II | Lancet, The | 2000 | 1,788 |
| 19 | Lyme Disease | New England Journal of Medicine | 1989 | 1,752 |
| 20 | Assessing the Effects of Physician-Patient Interactions on the Outcomes of Chronic Disease | Medical Care | 1989 | 1,730 |
| 21 | Missed Diagnoses of Acute Cardiac Ischemia in the Emergency Department | New England Journal of Medicine | 2000 | 1,648 |
| 22 | The Role of Vitamin D and Calcium in Type 2 Diabetes. A Systematic Review and Meta-Analysis | Journal of Clinical Endocrinology and Metabolism | 2007 | 1,644 |
| 23 | Expressing the Modification of Diet in Renal Disease Study Equation for Estimating Glomerular Filtration Rate with Standardized Serum Creatinine Values | Clinical Chemistry | 2007 | 1,587 |
| 24 | Comparison of the Atkins, Ornish, Weight Watchers, and Zone Diets for Weight Loss and Heart Disease Risk Reduction | JAMA - Journal of the American Medical Association | 2005 | 1,478 |
| 25 | Chronic kidney disease after nephrectomy in patients with renal cortical tumours: a retrospective cohort study | Lancet Oncology, The | 2006 | 1,456 |
| 26 | The molecular structure of green fluorescent protein | Nature Biotechnology | 1996 | 1,407 |
| 27 | Effects of Oral Tolvaptan in Patients Hospitalized for Worsening Heart FailureThe EVEREST Outcome Trial | JAMA - Journal of the American Medical Association | 2007 | 1,406 |
| 28 | Update of AAPM Task Group No. 43 Report: A revised AAPM protocol for brachytherapy dose calculations | Medical Physics | 2004 | 1,395 |
| 29 | The case of the misleading funnel plot | BMJ: British Medical Journal | 2006 | 1,353 |
| 30 | Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells | Cell | 2011 | 1,334 |
| 31 | A single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 1,320 |
| 32 | Effect of Failed Extubation on the Outcome of Mechanical Ventilation | Chest | 1997 | 1,303 |
| 33 | The molecular basis of blood coagulation | Cell | 1988 | 1,259 |
| 34 | Tyrosine Kinases as Targets for Cancer Therapy | New England Journal of Medicine | 2005 | 1,255 |
| 35 | Obesity Evaluation and Treatment: Expert Committee Recommendations | Pediatrics | 1998 | 1,219 |
| 36 | Effect of Left Ventricular Outflow Tract Obstruction on Clinical Outcome in Hypertrophic Cardiomyopathy | New England Journal of Medicine | 2003 | 1,217 |
| 37 | SMAD proteins control DROSHA-mediated microRNA maturation | Nature | 2008 | 1,196 |
| 38 | Five-Hundred Life-Saving Interventions and Their Cost-Effectiveness | Risk Analysis | 1995 | 1,171 |
| 39 | Primary Biliary Cirrhosis | New England Journal of Medicine | 2005 | 1,131 |
| 40 | Guidelines of care for the management of psoriasis and psoriatic arthritis | Journal of the American Academy of Dermatology | 2008 | 1,128 |
| 41 | Mammalian MAPK Signal Transduction Pathways Activated by Stress and Inflammation: A 10-Year Update | Physiological Reviews | 2012 | 1,122 |
| 42 | Ultrahigh-resolution, high-speed, Fourier domain optical coherence tomography and methods for dispersion compensation | Optics Express | 2004 | 1,095 |
| 43 | Chronic Kidney Disease as a Risk Factor for Cardiovascular Disease and All-Cause Mortality: A Pooled Analysis of Community-Based Studies | Journal of the American Society of Nephrology: JASN | 2004 | 1,072 |
| 44 | Cardiotoxicity of the cancer therapeutic agent imatinib mesylate | Nature Medicine | 2006 | 1,058 |
| 45 | The Swedish SF-36 Health Survey—I. Evaluation of data quality, scaling assumptions, reliability and construct validity across general populations in Sweden | Social Science and Medicine | 1995 | 1,052 |
| 46 | Linking clinical variables with health-related quality of life. A conceptual model of patient outcomes | JAMA - Journal of the American Medical Association | 1995 | 1,036 |
| 47 | Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice | Cell | 1993 | 1,009 |
| 48 | Toward a better definition of the restless legs syndrome | Movement Disorders | 1995 | 1,004 |
| 49 | Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission | Cancer Research | 2009 | 1,003 |
| 50 | A proposed classification for spinal and cranial dural arteriovenous fistulous malformations and implications for treatment | Journal of Neurosurgery | 1995 | 998 |
