| # | Title | Journal | Year | Citations |
|---|
| 1 | Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel | Blood | 2017 | 4,375 |
| 2 | K-rasMutations and Benefit from Cetuximab in Advanced Colorectal Cancer | New England Journal of Medicine | 2008 | 3,353 |
| 3 | Transcatheter Aortic-Valve Replacement with a Self-Expanding Valve in Low-Risk Patients | New England Journal of Medicine | 2019 | 2,530 |
| 4 | Non-invasive electrical and magnetic stimulation of the brain, spinal cord, roots and peripheral nerves: Basic principles and procedures for routine clinical and research application. An updated report from an I.F.C.N. Committee | Clinical Neurophysiology | 2015 | 1,957 |
| 5 | Catheter-based renal sympathetic denervation for resistant hypertension: a multicentre safety and proof-of-principle cohort study | Lancet, The | 2009 | 1,918 |
| 6 | International Myeloma Working Group consensus criteria for response and minimal residual disease assessment in multiple myeloma | Lancet Oncology, The | 2016 | 1,866 |
| 7 | Posthepatectomy liver failure: A definition and grading by the International Study Group of Liver Surgery (ISGLS) | Surgery | 2011 | 1,703 |
| 8 | Bile leakage after hepatobiliary and pancreatic surgery: A definition and grading of severity by the International Study Group of Liver Surgery | Surgery | 2011 | 1,596 |
| 9 | Guidelines for the management of hemophilia | Haemophilia | 2013 | 1,538 |
| 10 | Telaprevir for Retreatment of HCV Infection | New England Journal of Medicine | 2011 | 1,466 |
| 11 | Extracorporeal Membrane Oxygenation for 2009 Influenza A(H1N1) Acute Respiratory Distress Syndrome | JAMA - Journal of the American Medical Association | 2009 | 1,416 |
| 12 | Decompressive Craniectomy in Diffuse Traumatic Brain Injury | New England Journal of Medicine | 2011 | 1,395 |
| 13 | Lenalidomide plus Dexamethasone for Relapsed or Refractory Multiple Myeloma | New England Journal of Medicine | 2007 | 1,365 |
| 14 | Adjustable Gastric Banding and Conventional Therapy for Type 2 Diabetes | JAMA - Journal of the American Medical Association | 2008 | 1,297 |
| 15 | Estimating the global incidence of traumatic brain injury | Journal of Neurosurgery | 2019 | 1,291 |
| 16 | Bispectral index monitoring to prevent awareness during anaesthesia: the B-Aware randomised controlled trial | Lancet, The | 2004 | 1,269 |
| 17 | Nonalcoholic Fatty Liver Disease: Predictors of Nonalcoholic Steatohepatitis and Liver Fibrosis in the Severely Obese | Gastroenterology | 2001 | 1,246 |
| 18 | Peginterferon Alfa-2a plus Ribavirin for Chronic Hepatitis C Virus Infection in HIV-Infected Patients | New England Journal of Medicine | 2004 | 1,220 |
| 19 | Adjuvant Dabrafenib plus Trametinib in Stage IIIBRAF-Mutated Melanoma | New England Journal of Medicine | 2017 | 1,192 |
| 20 | Bronchiolitis obliterans syndrome 2001: an update of the diagnostic criteria | Journal of Heart and Lung Transplantation | 2002 | 1,185 |
| 21 | A consensus document for the selection of lung transplant candidates: 2014—An update from the Pulmonary Transplantation Council of the International Society for Heart and Lung Transplantation | Journal of Heart and Lung Transplantation | 2015 | 1,121 |
| 22 | Association analysis identifies 65 new breast cancer risk loci | Nature | 2017 | 1,099 |
| 23 | International Guidelines for the Selection of Lung Transplant Candidates: 2006 Update—A Consensus Report From the Pulmonary Scientific Council of the International Society for Heart and Lung Transplantation | Journal of Heart and Lung Transplantation | 2006 | 1,080 |
| 24 | Clinical recommendations for cardiovascular magnetic resonance mapping of T1, T2, T2* and extracellular volume: A consensus statement by the Society for Cardiovascular Magnetic Resonance (SCMR) endorsed by the European Association for Cardiovascular Imaging (EACVI) | Journal of Cardiovascular Magnetic Resonance | 2017 | 1,074 |
| 25 | Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer | Science Translational Medicine | 2016 | 1,036 |
| 26 | Osteoarthritis | Nature Reviews Disease Primers | 2016 | 1,011 |
| 27 | Evolution of Mortality over Time in Patients Receiving Mechanical Ventilation | American Journal of Respiratory and Critical Care Medicine | 2013 | 999 |
| 28 | Staphylococcus aureus Endocarditis | JAMA - Journal of the American Medical Association | 2005 | 990 |
| 29 | Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial | Lancet Neurology, The | 2008 | 971 |
| 30 | Surgery alone versus chemoradiotherapy followed by surgery for resectable cancer of the oesophagus: a randomised controlled phase III trial | Lancet Oncology, The | 2005 | 876 |
| 31 | Prognostic Accuracy of the SOFA Score, SIRS Criteria, and qSOFA Score for In-Hospital Mortality Among Adults With Suspected Infection Admitted to the Intensive Care Unit | JAMA - Journal of the American Medical Association | 2017 | 807 |
| 32 | Cracking the BAFF code | Nature Reviews Immunology | 2009 | 799 |
| 33 | Vestibular migraine: Diagnostic criteria | Journal of Vestibular Research: Equilibrium and Orientation | 2012 | 787 |
| 34 | Subtyping of Breast Cancer by Immunohistochemistry to Investigate a Relationship between Subtype and Short and Long Term Survival: A Collaborative Analysis of Data for 10,159 Cases from 12 Studies | PLoS Medicine | 2010 | 764 |
| 35 | Subcutaneous Golimumab Induces Clinical Response and Remission in Patients With Moderate-to-Severe Ulcerative Colitis | Gastroenterology | 2014 | 753 |
| 36 | Overflow of catecholamine neurotransmitters to the circulation: source, fate, and functions | Physiological Reviews | 1990 | 748 |
| 37 | Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes | American Journal of Human Genetics | 2019 | 711 |
| 38 | Nonalcoholic fatty liver disease: Improvement in liver histological analysis with weight loss | Hepatology | 2004 | 687 |
| 39 | Pulse pressure—a review of mechanisms and clinical relevance | Journal of the American College of Cardiology | 2001 | 678 |
| 40 | No Effects of Gluten in Patients With Self-Reported Non-Celiac Gluten Sensitivity After Dietary Reduction of Fermentable, Poorly Absorbed, Short-Chain Carbohydrates | Gastroenterology | 2013 | 676 |
| 41 | Predicting survival after ECMO for refractory cardiogenic shock: the survival after veno-arterial-ECMO (SAVE)-score | European Heart Journal | 2015 | 654 |
| 42 | Safety and efficacy of imatinib cessation for CML patients with stable undetectable minimal residual disease: results from the TWISTER study | Blood | 2013 | 641 |
| 43 | Predicting Survival after Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Failure. The Respiratory Extracorporeal Membrane Oxygenation Survival Prediction (RESP) Score | American Journal of Respiratory and Critical Care Medicine | 2014 | 620 |
| 44 | Adverse consequences of high sympathetic nervous activity in the failing human heart | Journal of the American College of Cardiology | 1995 | 614 |
| 45 | Validity and reliability of a postoperative quality of recovery score: the QoR-40 | British Journal of Anaesthesia | 2000 | 614 |
| 46 | Patient satisfaction after anaesthesia and surgery: results of a prospective survey of 10,811 patients | British Journal of Anaesthesia | 2000 | 607 |
| 47 | Subcutaneous Golimumab Maintains Clinical Response in Patients With Moderate-to-Severe Ulcerative Colitis | Gastroenterology | 2014 | 605 |
| 48 | Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders | Australian and New Zealand Journal of Psychiatry | 2015 | 600 |
| 49 | Iron-Export Ferroxidase Activity of β-Amyloid Precursor Protein Is Inhibited by Zinc in Alzheimer's Disease | Cell | 2010 | 597 |
| 50 | Catheter-based renal denervation in patients with uncontrolled hypertension in the absence of antihypertensive medications (SPYRAL HTN-OFF MED): a randomised, sham-controlled, proof-of-concept trial | Lancet, The | 2017 | 597 |
