| # | Title | Journal | Year | Citations |
|---|
| 1 | Randomized Phase III Study of Gemcitabine Plus S-1, S-1 Alone, or Gemcitabine Alone in Patients With Locally Advanced and Metastatic Pancreatic Cancer in Japan and Taiwan: GEST Study | Journal of Clinical Oncology | 2013 | 548 |
| 2 | TAS-102 monotherapy for pretreated metastatic colorectal cancer: a double-blind, randomised, placebo-controlled phase 2 trial | Lancet Oncology, The | 2012 | 267 |
| 3 | Multiple calcium channels and kinases mediate α7 nicotinic receptor neuroprotection in PC12 cells | Journal of Neurochemistry | 2005 | 53 |
| 4 | Effects at a distance in α7 nAChR selective agonists: benzylidene substitutions that regulate potency and efficacy | Neuropharmacology | 2004 | 32 |
| 5 | Intracellular Thymidylate Synthase Inhibition by Trifluorothymidine in FM3A Cells | Nucleosides, Nucleotides and Nucleic Acids | 2004 | 30 |
| 6 | One‐year safety and efficacy study of bilastine treatment in Japanese patients with chronic spontaneous urticaria or pruritus associated with skin diseases | Journal of Dermatology | 2017 | 25 |
| 7 | Therapeutic potential of antisense oligodeoxynucleotides to down-regulate thymidylate synthase in mesothelioma | Molecular Cancer Therapeutics | 2006 | 24 |
| 8 | Prolonged bleeding time induced by anticoagulant glycosaminoglycans in dogs is associated with the inhibition of thrombin-induced platelet aggregation | Thrombosis Research | 2003 | 17 |
| 9 | Effects of nicotine, pilocarpine, and tetrahydroaminoacridine on hippocampal theta waves in freely moving rabbits | European Journal of Pharmacology | 1998 | 16 |
| 10 | Activity of TAS4464, a novel NEDD8 activating enzyme E1 inhibitor, against multiple myeloma via inactivation of nuclear factor κB pathways | Cancer Science | 2019 | 16 |
| 11 | Cardiovascular Profile of MPC-1304, a Novel Dihydropyridine Calcium Antagonist | Journal of Cardiovascular Pharmacology | 1993 | 14 |
| 12 | Secondary abnormality of carnitine biosynthesis results from carnitine reabsorptional system defect in juvenile visceral steatosis mice | Biochimica Et Biophysica Acta - Molecular Basis of Disease | 1997 | 13 |
| 13 | Dystrophin, Utrophin and β-Dystroglyoan Expression in Skeletal Muscle from Patients with Becker Muscular Dystrophy | Journal of Neuropathology and Experimental Neurology | 1996 | 12 |
| 14 | Orotate phosphoribosyltransferase levels measured by a newly established enzyme-linked immunosorbent assay in gastric carcinoma | Cancer Science | 2006 | 11 |
| 15 | Phase I dose-escalating study of TAS-106 in combination with carboplatin in patients with solid tumors | Investigational New Drugs | 2014 | 8 |
| 16 | Interaction of suplatast tosilate (IPD) with chloride channels in human blood eosinophils: a potential mechanism underlying its anti-allergic and anti-asthmatic effects | Clinical and Experimental Allergy | 2007 | 5 |
| 17 | Comments from the Behavioral Teratology Committee of the Japanese Teratology Society on OECD Guideline for the Testing of Chemicals, Proposal for a New Guideline 426, Developmental Neurotoxicity Study, Draft Document (September 2003) | Congenital Anomalies (discontinued) | 2004 | 3 |
| 18 | OP0075 TAS5315, A Novel Bruton's Tyrosine Kinase (BTK) Inhibitor, Demonstrates Potent Efficacy in Mouse Collagen-Induced Arthritis Model | Annals of the Rheumatic Diseases | 2015 | 3 |
| 19 | A phase I trial of TAS-102 administered on a three times a day schedule in patients with solid tumors | Journal of Clinical Oncology | 2006 | 2 |
| 20 | Randomized phase II study of S-1/CDDP plus TSU-68 versus S-1/CDDP in patients with advanced gastric cancer. | Journal of Clinical Oncology | 2013 | 1 |
| 21 | Abstract 1287: The dual IAP antagonist, ASTX660, increases the anti-tumor activity of paclitaxel in preclinical models of triple-negative breast cancer in vivo | Cancer Research | 2016 | 1 |
| 22 | Abstract A33: ASTX660, a dual XIAP and cIAP antagonist, potentiates the anti-PD-L1 antibody therapy in mouse tumor models | | 2017 | 1 |
| 23 | FRI0079 TAS5315, a novel bruton's tyrosine kinase inhibitor, improve bone mineral density (BMD) and bone erosion via inhibition of osteoclast activation in murine model for rheumatoid arthritis | | 2017 | 0 |
| 24 | Age-associated Clinico-Pathological Characteristics in Barrier-reared SHR-SP/Tih | International Heart Journal | 1993 | 0 |
| 25 | Abstract 1981: Drug-tolerant gastric cancer cell subpopulation enriched by 5-fluorouracil acquires malignant phenotype | | 2014 | 0 |
| 26 | Abstract PR13: p53-related protein kinase is a novel prognostic marker and therapeutic target in multiple myeloma | | 2017 | 0 |
