# | Title | Journal | Year | Citations |
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1 | Identification of the haematopoietic stem cell niche and control of the niche size | Nature | 2003 | 2,633 |
2 | An operational definition of epigenetics: Figure 1. | Genes and Development | 2009 | 1,457 |
3 | The developmental transcriptome of Drosophila melanogaster | Nature | 2011 | 1,379 |
4 | The CRAPome: a contaminant repository for affinity purification–mass spectrometry data | Nature Methods | 2013 | 1,353 |
5 | Structure of the Cul1–Rbx1–Skp1–F boxSkp2 SCF ubiquitin ligase complex | Nature | 2002 | 1,322 |
6 | The complete sequence of a human genome | Science | 2022 | 1,222 |
7 | Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1 | Nature Genetics | 1997 | 1,184 |
8 | Histone H3 Methylation by Set2 Directs Deacetylation of Coding Regions by Rpd3S to Suppress Spurious Intragenic Transcription | Cell | 2005 | 1,154 |
9 | STEM CELL NICHE: Structure and Function | Annual Review of Cell and Developmental Biology | 2005 | 1,082 |
10 | Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein | Nature | 2011 | 1,060 |
11 | Statistical Analysis of Membrane Proteome Expression Changes inSaccharomycescerevisiae | Journal of Proteome Research | 2006 | 1,042 |
12 | The Genome of the Sea Urchin Strongylocentrotus purpuratus | Science | 2006 | 1,018 |
13 | Histone acetyltransferase complexes: one size doesn't fit all | Nature Reviews Molecular Cell Biology | 2007 | 959 |
14 | BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt–β-catenin signaling | Nature Genetics | 2004 | 948 |
15 | The COMPASS Family of Histone H3K4 Methylases: Mechanisms of Regulation in Development and Disease Pathogenesis | Annual Review of Biochemistry | 2012 | 896 |
16 | New Nomenclature for Chromatin-Modifying Enzymes | Cell | 2007 | 849 |
17 | Histone exchange, chromatin structure and the regulation of transcription | Nature Reviews Molecular Cell Biology | 2015 | 776 |
18 | PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention | Nature | 2006 | 767 |
19 | Quantitative Interaction Proteomics and Genome-wide Profiling of Epigenetic Histone Marks and Their Readers | Cell | 2010 | 710 |
20 | The stem cell niches in bone | Journal of Clinical Investigation | 2006 | 667 |
21 | Normal Stem Cells and Cancer Stem Cells: The Niche Matters: Figure 1. | Cancer Research | 2006 | 663 |
22 | THE GENETICS AND MOLECULAR BIOLOGY OF THE SYNAPTONEMAL COMPLEX | Annual Review of Cell and Developmental Biology | 2004 | 631 |
23 | Histone Ubiquitination: Triggering Gene Activity | Molecular Cell | 2008 | 610 |
24 | Acetylation by Tip60 Is Required for Selective Histone Variant Exchange at DNA Lesions | Science | 2004 | 602 |
25 | A two-color acid-free cartilage and bone stain for zebrafish larvae | Biotechnic and Histochemistry | 2007 | 598 |
26 | Sequencing of the sea lamprey (Petromyzon marinus) genome provides insights into vertebrate evolution | Nature Genetics | 2013 | 588 |
27 | Histone H4 lysine 16 acetylation regulates cellular lifespan | Nature | 2009 | 580 |
28 | The hardwiring of development: organization and function of genomic regulatory systems | Development (Cambridge) | 1997 | 576 |
29 | Covalent modifications of histones during development and disease pathogenesis | Nature Structural and Molecular Biology | 2007 | 574 |
30 | Telomere-to-telomere assembly of a complete human X chromosome | Nature | 2020 | 549 |
31 | Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast | Nature | 2010 | 521 |
32 | The Language of Histone Crosstalk | Cell | 2010 | 505 |
33 | Detection of functional haematopoietic stem cell niche using real-time imaging | Nature | 2009 | 504 |
34 | AFF4, a Component of the ELL/P-TEFb Elongation Complex and a Shared Subunit of MLL Chimeras, Can Link Transcription Elongation to Leukemia | Molecular Cell | 2010 | 504 |
35 | Quantitative proteomic analysis of distinct mammalian Mediator complexes using normalized spectral abundance factors | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 495 |
36 | The Segmentation Clock: Converting Embryonic Time into Spatial Pattern | Science | 2003 | 487 |
37 | Megakaryocytes maintain homeostatic quiescence and promote post-injury regeneration of hematopoietic stem cells | Nature Medicine | 2014 | 470 |
38 | RAD6-Mediated Transcription-Coupled H2B Ubiquitylation Directly Stimulates H3K4 Methylation in Human Cells | Cell | 2009 | 453 |
39 | Germline Stem Cells Anchored by Adherens Junctions in the Drosophila Ovary Niches | Science | 2002 | 444 |
40 | Chromosome Choreography: The Meiotic Ballet | Science | 2003 | 441 |
41 | Integrative structure and functional anatomy of a nuclear pore complex | Nature | 2018 | 435 |
42 | Reprogramming metastatic tumour cells with embryonic microenvironments | Nature Reviews Cancer | 2007 | 434 |
43 | Myoblast fusion: lessons from flies and mice | Development (Cambridge) | 2012 | 433 |
44 | Signals and Combinatorial Functions of Histone Modifications | Annual Review of Biochemistry | 2011 | 429 |
45 | A Complex Oscillating Network of Signaling Genes Underlies the Mouse Segmentation Clock | Science | 2006 | 418 |
46 | Molecular implementation and physiological roles for histone H3 lysine 4 (H3K4) methylation | Current Opinion in Cell Biology | 2008 | 418 |
47 | Histone modification: cause or cog? | Trends in Genetics | 2011 | 415 |
48 | VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases | Genes and Development | 2004 | 405 |
49 | Control of segment number in vertebrate embryos | Nature | 2008 | 398 |
50 | The road to maturation: somatic cell interaction and self-organization of the mammalian oocyte | Nature Reviews Molecular Cell Biology | 2013 | 398 |