| # | Title | Journal | Year | Citations |
|---|
| 1 | Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria | Annals of Neurology | 2011 | 8,001 |
| 2 | 2013 Classification Criteria for Systemic Sclerosis: An American College of Rheumatology/European League Against Rheumatism Collaborative Initiative | Arthritis and Rheumatism | 2013 | 2,359 |
| 3 | 2013 classification criteria for systemic sclerosis: an American college of rheumatology/European league against rheumatism collaborative initiative | Annals of the Rheumatic Diseases | 2013 | 1,705 |
| 4 | Second European evidence-based consensus on the prevention, diagnosis and management of opportunistic infections in inflammatory bowel disease | Journal of Crohn's and Colitis | 2014 | 804 |
| 5 | Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial | Lancet, The | 2019 | 804 |
| 6 | Selective Activation of Inflammatory Pathways by Intermittent Hypoxia in Obstructive Sleep Apnea Syndrome | Circulation | 2005 | 793 |
| 7 | Synovial tissue inflammation in early and late osteoarthritis | Annals of the Rheumatic Diseases | 2005 | 779 |
| 8 | T cells in multiple sclerosis and experimental autoimmune encephalomyelitis | Clinical and Experimental Immunology | 2010 | 761 |
| 9 | European League Against Rheumatism (EULAR) recommendations for the management of psoriatic arthritis with pharmacological therapies: 2015 update | Annals of the Rheumatic Diseases | 2016 | 743 |
| 10 | Sleep apnoea as an independent risk factor for cardiovascular disease: current evidence, basic mechanisms and research priorities | European Respiratory Journal | 2006 | 731 |
| 11 | Group for Research and Assessment of Psoriasis and Psoriatic Arthritis 2015 Treatment Recommendations for Psoriatic Arthritis | Arthritis and Rheumatology | 2016 | 726 |
| 12 | The Systemic Inflammatory Response to Cardiac Surgery | Anesthesiology | 2002 | 709 |
| 13 | Recommendations for reporting tumor budding in colorectal cancer based on the International Tumor Budding Consensus Conference (ITBCC) 2016 | Modern Pathology | 2017 | 652 |
| 14 | Carcinoembryonic Antigen as a Marker for Colorectal Cancer: Is It Clinically Useful? | Clinical Chemistry | 2001 | 619 |
| 15 | EULAR recommendations for the management of psoriatic arthritis with pharmacological therapies: 2019 update | Annals of the Rheumatic Diseases | 2020 | 609 |
| 16 | Systematic review of preoperative, intraoperative and postoperative risk factors for colorectal anastomotic leaks | British Journal of Surgery | 2015 | 600 |
| 17 | Pathological response following long-course neoadjuvant chemoradiotherapy for locally advanced rectal cancer | Histopathology | 2005 | 540 |
| 18 | Systematic review and meta-analysis of outcomes following pathological complete response to neoadjuvant chemoradiotherapy for rectal cancer | British Journal of Surgery | 2012 | 512 |
| 19 | EULAR evidence-based recommendations for the diagnosis of knee osteoarthritis | Annals of the Rheumatic Diseases | 2010 | 499 |
| 20 | Clinical Course of acute‐on‐chronic liver failure syndrome and effects on prognosis | Hepatology | 2015 | 493 |
| 21 | Treating axial spondyloarthritis and peripheral spondyloarthritis, especially psoriatic arthritis, to target: 2017 update of recommendations by an international task force | Annals of the Rheumatic Diseases | 2018 | 484 |
| 22 | ECCO Guidelines on Therapeutics in Crohn’s Disease: Surgical Treatment | Journal of Crohn's and Colitis | 2020 | 478 |
| 23 | A prospective, clinical and radiological study of early psoriatic arthritis: an early synovitis clinic experience | British Journal of Rheumatology | 2003 | 475 |
| 24 | Emergence and spread of a human-transmissible multidrug-resistant nontuberculous mycobacterium | Science | 2016 | 462 |
| 25 | Heart Failure Association of the European Society of Cardiology practical guidance on the use of natriuretic peptide concentrations | European Journal of Heart Failure | 2019 | 446 |
| 26 | Long-term Effects of Nasal Continuous Positive Airway Pressure Therapy on Cardiovascular Outcomes in Sleep Apnea Syndrome | Chest | 2005 | 439 |
| 27 | Tumour markers in colorectal cancer: European Group on Tumour Markers (EGTM) guidelines for clinical use | European Journal of Cancer | 2007 | 437 |
| 28 | Effect of natalizumab on clinical and radiological disease activity in multiple sclerosis: a retrospective analysis of the Natalizumab Safety and Efficacy in Relapsing-Remitting Multiple Sclerosis (AFFIRM) study | Lancet Neurology, The | 2009 | 430 |
| 29 | Diagnostic delay of more than 6 months contributes to poor radiographic and functional outcome in psoriatic arthritis | Annals of the Rheumatic Diseases | 2015 | 424 |
| 30 | Diastolic Heart Failure | Circulation | 2007 | 407 |
| 31 | The ‘psoriatic march’: a concept of how severe psoriasis may drive cardiovascular comorbidity | Experimental Dermatology | 2011 | 399 |
| 32 | 2016 update of the EULAR recommendations for the management of early arthritis | Annals of the Rheumatic Diseases | 2017 | 393 |
| 33 | Heterogeneity of tumor-induced gene expression changes in the human metabolic network | Nature Biotechnology | 2013 | 381 |
| 34 | A Combination of Molecular Markers and Clinical Features Improve the Classification of Pancreatic Cysts | Gastroenterology | 2015 | 376 |
| 35 | Serum Tumor Markers in Breast Cancer: Are They of Clinical Value? | Clinical Chemistry | 2006 | 367 |
| 36 | Clinical use of biomarkers in breast cancer: Updated guidelines from the European Group on Tumor Markers (EGTM) | European Journal of Cancer | 2017 | 363 |
| 37 | Guidelines for autopsy investigation of sudden cardiac death: 2017 update from the Association for European Cardiovascular Pathology | Virchows Archiv Fur Pathologische Anatomie Und Physiologie Und Fur Klinische Medizin | 2017 | 357 |
| 38 | Neratinib Plus Capecitabine Versus Lapatinib Plus Capecitabine in HER2-Positive Metastatic Breast Cancer Previously Treated With ≥ 2 HER2-Directed Regimens: Phase III NALA Trial | Journal of Clinical Oncology | 2020 | 355 |
| 39 | Hypoxia, oxidative stress and inflammation | Free Radical Biology and Medicine | 2018 | 343 |
| 40 | Innate and adaptive lymphoid cells in the human liver | Immunological Reviews | 2000 | 341 |
| 41 | The taxanes: an update | Lancet, The | 2000 | 336 |
| 42 | Association of Initial Disease-Modifying Therapy With Later Conversion to Secondary Progressive Multiple Sclerosis | JAMA - Journal of the American Medical Association | 2019 | 336 |
| 43 | Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis | Nature Genetics | 2010 | 334 |
| 44 | Cardiac Rhythm Disturbances in the Obstructive Sleep Apnea Syndrome | Chest | 2000 | 330 |
| 45 | Predictors of Elevated Nuclear Factor-κB–dependent Genes in Obstructive Sleep Apnea Syndrome | American Journal of Respiratory and Critical Care Medicine | 2006 | 325 |
| 46 | PROGRESSIVE ENCEPHALOMYELITIS, RIGIDITY, AND MYOCLONUS: A NOVEL GLYCINE RECEPTOR ANTIBODY | Neurology | 2008 | 324 |
| 47 | Pain sensitization in people with knee osteoarthritis: a systematic review and meta-analysis | Osteoarthritis and Cartilage | 2015 | 319 |
| 48 | Restoring Cystic Fibrosis Transmembrane Conductance Regulator Function Reduces Airway Bacteria and Inflammation in People with Cystic Fibrosis and Chronic Lung Infections | American Journal of Respiratory and Critical Care Medicine | 2017 | 317 |
| 49 | A patient-derived and patient-reported outcome measure for assessing psoriatic arthritis: elaboration and preliminary validation of the Psoriatic Arthritis Impact of Disease (PsAID) questionnaire, a 13-country EULAR initiative | Annals of the Rheumatic Diseases | 2014 | 314 |
| 50 | Cardiovascular disease in obstructive sleep apnoea syndrome: the role of intermittent hypoxia and inflammation | European Respiratory Journal | 2009 | 289 |
